Abstract: The present disclosure provides a composition comprising a compound of formula (I) or a physiologically acceptable salt thereof, in which the compound of formula (I) or a physiologically acceptable salt thereof has a HPLC purity of ?90%; wherein R1, R2, X and n are as defined herein. The present disclosure further provides use of the composition according to the present disclosure for preparing and/or purifying a composition comprising a salt of the compound of formula (I), and a method for treating a disease caused by a Coronavirus which comprises administering the composition of the present disclosure to a subject. The composition of the present disclosure comprises the compound of formula (I) with high purity, and has good fluidity and anti-caking property; moreover, the claimed composition comprising the compound of formula (I)) with high purity is more suitable for preparing a composition comprising a salt of the compound of formula (I) with higher purity.

Abstract: The present invention provides a composition comprising a compound of formula (I) or a physiologically acceptable salt thereof, in which the compound of formula (I) or a physiologically acceptable salt thereof has a HPLC purity of ?90%; wherein R1, R2, X and n are as defined herein. The present invention further provides use of the composition according to the present invention for preparing and/or purifying a composition comprising a salt of the compound of formula (I), and a method for treating a disease caused by a coronavirus which comprises administering the composition of the present invention to a subject. The composition of the present invention comprises the compound of formula (I) with high purity, and has good fluidity and anti-caking property; moreover, the claimed composition comprising the compound of formula (I)) with high purity is more suitable for preparing a composition comprising a salt of the compound of formula (I) with higher purity.

Abstract: The present disclosure provides a crystal form comprising a compound of Formula (I) and fumaric acid, wherein the crystal form satisfies at least one of the following conditions: (1) a particle size D90 of the active pharmaceutical ingredient ranges from about 5 ?m to about 60 ?m; and (2) a particle size D50 of the active pharmaceutical ingredient does not exceed about 30 ?m; a pharmaceutical composition containing the crystal form, and a method for treating coronavirus-induced diseases by using the crystal form. The crystal form of the present disclosure enables the pharmaceutical composition containing the crystal form to have advantages such as a higher dissolution rate, a higher dissolution, and the like.

Abstract: The present invention provides a composition comprising a compound of formula (I) or a physiologically acceptable salt thereof, in which the compound of formula (I) or a physiologically acceptable salt thereof has a HPLC purity of ? 90%; wherein R1, R2, X and n are as defined herein. The present invention further provides use of the composition according to the present invention for preparing and/or purifying a composition comprising a salt of the compound of formula (I), and a method for treating a disease caused by a coronavirus which comprises administering the composition of the present invention to a subject. The composition of the present invention comprises the compound of formula (I) with high purity, and has good fluidity and anti-caking property; moreover, the claimed composition comprising the compound of formula (I)) with high purity is more suitable for preparing a composition comprising a salt of the compound of formula (I) with higher purity.

Abstract: A method for displaying a covering on a panoramic map image includes: acquiring covering information to be displayed, in which the covering information includes a plurality of coverings; acquiring a set of vertices of a maximum circumscribed polyhedron for each covering in a three-dimensional coordinate system of a panoramic scene; acquiring a mapped set of vertices of the maximum circumscribed polyhedron of each covering by mapping the set of vertices to a sphere; determining an overlapping result among the plurality of coverings based on the mapped set of vertices of each covering; and determining a target covering from the plurality of coverings based on the overlapping result, and displaying the target covering on the panoramic map image.

Abstract: The present disclosure provides an active pharmaceutical ingredient containing a crystal form including a compound of Formula (I) and fumaric acid. An X-ray powder diffraction pattern of the crystal form obtained by using Cu-K? radiation includes at least three peaks selected from the group consisting of 10.94°±0.2° 2?, 19.06°±0.2° 2?, 23.50°±0.2° 2?, and 24.66°±0.2° 2?; a particle size D90 of the active pharmaceutical ingredient is smaller than or equal to 20 ?m, and a particle size D50 of the active pharmaceutical ingredient is smaller than or equal to 10 ?m.

Abstract: The present disclosure provides a crystal form of a compound and fumaric acid, an active pharmaceutical ingredient and a pharmaceutical composition containing the same, and a method for treating coronavirus-induced diseases a using the same. In particular, the crystal form of the present disclosure comprises the compound of Formula (I) and fumaric acid, and the X-ray powder diffraction pattern of the crystal form obtained using Cu-K? radiation includes at least three peaks selected from the group consisting of: 0.94°±0.2° 2?, 19.06°±0.2° 2?, 23.50°±0.2° 2?, and 24.66°±0.2° 2?. The crystal form of the present disclosure has a high purity, good stability, and a high melting point.

Abstract: The present disclosure discloses a map data processing method, a device, a storage medium and a program product, and relates to intelligent transportation, automatic driving, electronic map and other fields in computer technology. A specific solution is: determining, according to coordinates of vertexes of a tile included in panoramic map data, coordinates of mapping points of the tile on a plane where a viewport is located; determining a bounding box of the mapping points according to the coordinates of the mapping points; according to whether there is an overlapping area between the bounding box of the mapping points and a visible range corresponding to the viewport, determining whether the tile falls within the visible range, thus determining the indexes of all the tiles falling within the visible range. In this way, the indexes of the tiles falling within the visible range corresponding to the current viewport can be determined accurately.

Abstract: A method for displaying a covering on a panoramic map image includes: acquiring covering information to be displayed, in which the covering information includes a plurality of coverings; acquiring a set of vertices of a maximum circumscribed polyhedron for each covering in a three-dimensional coordinate system of a panoramic scene; acquiring a mapped set of vertices of the maximum circumscribed polyhedron of each covering by mapping the set of vertices to a sphere; determining an overlapping result among the plurality of coverings based on the mapped set of vertices of each covering; and determining a target covering from the plurality of coverings based on the overlapping result, and displaying the target covering on the panoramic map image.

Abstract: The disclosure discloses a method for assisting quality inspection of map data and an electronic device. The detailed implementation includes: obtaining at least one piece of map query data matching an area to be inspected; obtaining a first map image matching each piece of map query data by a first map client and obtaining a second map image matching each piece of map query data by a second map client, the first map client being adapted with map data to be online, and the second map client being adapted with online map data; and generating at least one pair of contrast images for quality inspection based on the first map image and the second map image, in which each pair of contrast images includes map images determined by the first map client and the second map client for the same map query data.

Abstract: A question answering processing method and apparatus, and a storage medium is disclosed herein. The detailed implementation solution includes: receiving a speech question inputted by a user; obtaining an answer set corresponding to the speech question, the answer set including a plurality of candidate answers, and each candidate answer corresponding to a region identification; obtaining a current region identification of the user, and determining whether the answer set includes the current region identification; and in a case that the answer set includes the current region identification, obtaining a first candidate answer corresponding to the current region identification, and feeding the plurality of candidate answers sorted with the first candidate answer as a first place back to the user.

Abstract: The present disclosure provides a volume adjustment method, a terminal device, a storage medium, and an electronic device. The volume adjustment method provided by the present disclosure includes: acquiring ambient sound of current environment first and determining the main sound included in the ambient sound, where the main sound has a strongest preset sound characteristic among all sound types included in the ambient sound, and then adjusting a volume of the audio sound according to the main sound and a preset sound adjustment rule. The volume adjustment method provided by the present disclosure may enable the terminal device to adopt an adaptive adjustment manner to control the volume under different working environments, thereby outputting a volume that meets a user's current demand for the user.

Abstract: The present disclosure provides a volume adjustment method, a terminal device, a storage medium, and an electronic device. The volume adjustment method provided by the present disclosure includes: acquiring ambient sound of current environment first and determining the main sound included in the ambient sound, where the main sound has a strongest preset sound characteristic among all sound types included in the ambient sound, and then adjusting a volume of the audio sound according to the main sound and a preset sound adjustment rule. The volume adjustment method provided by the present disclosure may enable the terminal device to adopt an adaptive adjustment manner to control the volume under different working environments, thereby outputting a volume that meets a user's current demand for the user.

Abstract: A speech broadcast method, device and terminal are provided. The method includes: obtaining a current conversation speech from a user; identifying a tone type of the current conversation speech with a tone identification model; selecting a broadcast tone according to the identified tone type; and generating a broadcast speech according to the selected broadcast tone. A tone type of a current conversation speech is identified with a tone identification model, and a broadcast tone for broadcasting is selected, so that the broadcast speech generated by using the broadcast tone suitable to a user mood, improving cordial feeling during the interaction, and providing a more user-friendly interactive experience.