Patents by Inventor Tapan Audhya

Tapan Audhya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetra and penta-peptides useful in regulating the immune system
    Patent number: 5298490
    Abstract: Tetrapeptides and pentapeptides are disclosed which are capable of regulating the function of cells of the mammalian immune system. Also provided are pharmaceutical compositions containing the peptides and methods of use thereof.
    Type: Grant
    Filed: January 9, 1990
    Date of Patent: March 29, 1994
    Assignee: Immunobiology Research Institute, Inc.
    Inventors: George Heavner, Gideon Goldstein, Tapan Audhya
  • Peptides useful in regulating the immune and nervous systems
    Patent number: 5215964
    Abstract: Pentapeptides are disclosed which are capable of regulating the function of cells of the mammalian immune and/or nervous system. Also provided are pharmaceutical compositions containing the peptides and methods of use thereof.
    Type: Grant
    Filed: June 3, 1991
    Date of Patent: June 1, 1993
    Assignee: Immunobiology Research Institute, Inc.
    Inventors: Gideon Goldstein, Tapan Audhya, George Heavner, Mohmed K. Anwer
  • Stabilized aqueous formulations of thymopentin
    Patent number: 5140010
    Abstract: The present invention provides a method for preparing aqueous formulations of thymopentin, which method permits the peptide to retain its biological activity during storage at room temperature.
    Type: Grant
    Filed: March 6, 1991
    Date of Patent: August 18, 1992
    Assignee: Immunobiology Research Institute
    Inventors: Gideon Goldstein, Tapan Audhya
  • Compositions containing thymopentin for topical treatment of skin disorders
    Patent number: 5036050
    Abstract: A composition for use in the topical treatment of skin disorders such as dermatitis or poison ivy, which comprises an effective amount of thymopentin and a suitable carrier is provided. A method for treating skin disorders and a method for making a topical composition are disclosed.
    Type: Grant
    Filed: December 19, 1989
    Date of Patent: July 30, 1991
    Assignee: Immunobiology Research Institute, Inc.
    Inventors: Tapan Audhya, Krishnamurthy Venkatasubramanian, Gideon Goldstein
  • Probursin
    Patent number: 4994554
    Abstract: A multi-functional mammalian peptide probursin isolated in purified form, produced synthetically or recombinantly can be used therapeutically for treatment of immune disorders and tumor inhibition.
    Type: Grant
    Filed: December 20, 1988
    Date of Patent: February 19, 1991
    Assignee: Immunobiology Research Institute, Inc.
    Inventors: Tapan Audhya, Gideon Goldstein, George Heavner
  • Human splenin
    Patent number: 4923964
    Abstract: The present invention is directed to the protein human splenin (hsP), substantially free of material associated with the protein in its natural environment in the human spleen. In particular, the present invention relates to such isolated or synthesized human splenin having the amino acid residue sequence:-GLY-LEU-PRO-LYS-GLU-VAL-PRO-ALA-VAL-LEU-THR-LYS-GLN-LYS -LEU-LYS-SER-GLU-LEU-VAL-ALA-ASN-ASN-VAL-THR-LEU-PRO-ALA -GLY-GLU-MET-ARG-LYS-ALA-VAL-TYR-VAL-GLU-LEU-TYR-LEU-GLY -SER-LEU-THR-ALA-GLU-HIS-.Additionally, the present invention relates to a therapeutic composition of matter comprising a therapeutically effective amount of the hsP having the above sequence and a pharmaceutically acceptible carrier.
    Type: Grant
    Filed: May 22, 1987
    Date of Patent: May 8, 1990
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Gideon Goldstein, Tapan Audhya
  • B cell differentiating peptides and conjugates thereof
    Patent number: 4866121
    Abstract: Synthetic peptides which possess the ability to specifically induce the differentiation of precursor B cells into mature B-cells capable of producing antibody.
    Type: Grant
    Filed: June 23, 1988
    Date of Patent: September 12, 1989
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Tapan Audhya, Daniel J. Kroon, George Heavner, Gideon Goldstein
  • B-cell differentiating peptides
    Patent number: 4783442
    Abstract: Synthetic peptides which possess the ability to specifically induce the differentiation of precursor B cells into mature B-cells capable of producing antibody.
    Type: Grant
    Filed: April 21, 1986
    Date of Patent: November 8, 1988
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Tapan Audhya, Daniel J. Kroon, George Heavner, Gideon Goldstein
  • Potent thymopentin analogs
    Patent number: 4629723
    Abstract: Immunoregulating peptides are disclosed which are more potent than thymopentin or splenin and are useful for their effects on the immune system, especially the treatment of thymic deficiencies.
    Type: Grant
    Filed: June 27, 1984
    Date of Patent: December 16, 1986
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Gideon Goldstein, George Heavner, Daniel Kroon, Tapan Audhya
  • Bursopoietin
    Patent number: 4584284
    Abstract: A synthetic peptide which possesses the ability to specifically induce the differentiation of precursor B cells into mature B-cells capable of producing antibody.
    Type: Grant
    Filed: January 31, 1985
    Date of Patent: April 22, 1986
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Tapan Audhya, Daniel J. Kroon, George Heavner, Gideon Goldstein
  • Conformationally restricted thymopentin-like compounds
    Patent number: 4547489
    Abstract: Immunoregulating peptides are disclosed which are cyclic peptides similar to thymopentin. These peptides are useful for their effects on the immune system, especially the treatment of thymic deficiencies.
    Type: Grant
    Filed: June 11, 1984
    Date of Patent: October 15, 1985
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Gideon Goldstein, George Heavner, Tapan Audhya, Foe-Siong Tjoeng
  • Enzyme-resistant immunomodulatory peptides
    Patent number: 4505853
    Abstract: Peptides which have thymopoeitin-like or splenin-like activity combined with greatly increased resistance to degradation by enzymes. The peptides are useful for treatment of immunoregulatory disorders. Also provided are methods of treating immunoregulatory disorders and compositions used in these methods.
    Type: Grant
    Filed: November 18, 1983
    Date of Patent: March 19, 1985
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Gideon Goldstein, George Heavner, Daniel Kroon, Tapan Audhya
  • Potent thymopentin analogs
    Patent number: RE34165
    Abstract: Immunoregulating peptides are disclosed which are more potent than thymopentin or splenin and are useful for their effects on the immune system, especially the treatment of thymic deficiencies.
    Type: Grant
    Filed: April 25, 1990
    Date of Patent: January 19, 1993
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Gideon Goldstein, George Heavner, Daniel Kroon, Tapan Audhya