Patents by Inventor Tapas K. De

Tapas K. De has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHOSPHOLIPID-COATED THERAPEUTIC AGENT NANOPARTICLES AND RELATED METHODS
    Publication number: 20180153818
    Abstract: Phospholipid-coated nanoparticles containing a therapeutic agent, compositions that include the nanoparticles, and methods for making and using the nanoparticles and compositions.
    Type: Application
    Filed: September 14, 2017
    Publication date: June 7, 2018
    Applicant: Autotelic LLC
    Inventors: Vuong Trieu, Tapas K. De
  • Immediate release phospholipid-coated therapeutic agent nanoparticles and related methods
    Patent number: 9763892
    Abstract: Phospholipid-coated nanoparticles containing a therapeutic agent, compositions that include the nanoparticles, and methods for making and using the nanoparticles and compositions.
    Type: Grant
    Filed: July 12, 2016
    Date of Patent: September 19, 2017
    Assignee: Autotelic LLC
    Inventors: Vuong Trieu, Tapas K. De
  • PHOSPHOLIPID-COATED THERAPEUTIC AGENT NANOPARTICLES AND RELATED METHODS
    Publication number: 20160346219
    Abstract: Phospholipid-coated nanoparticles containing a therapeutic agent, compositions that include the nanoparticles, and methods for making and using the nanoparticles and compositions.
    Type: Application
    Filed: July 12, 2016
    Publication date: December 1, 2016
    Applicant: Autotelic LLC
    Inventors: Vuong Trieu, Tapas K. De
  • PHOSPHOLIPID-COATED THERAPEUTIC AGENT NANOPARTICLES AND RELATED METHODS
    Publication number: 20160346221
    Abstract: Phospholipid-coated nanoparticles containing a therapeutic agent, compositions that include the nanoparticles, and methods for making and using the nanoparticles and compositions.
    Type: Application
    Filed: July 12, 2016
    Publication date: December 1, 2016
    Applicant: Autotelic LLC
    Inventors: Vuong Trieu, Tapas K. De
  • PHOSPHOLIPID-COATED THERAPEUTIC AGENT NANOPARTICLES AND RELATED METHODS
    Publication number: 20160346220
    Abstract: Phospholipid-coated nanoparticles containing a therapeutic agent, compositions that include the nanoparticles, and methods for making and using the nanoparticles and compositions.
    Type: Application
    Filed: July 12, 2016
    Publication date: December 1, 2016
    Applicant: Autotelic LLC
    Inventors: Vuong Trieu, Tapas K. De
  • Methods and compositions for treating proliferative diseases
    Patent number: 7780984
    Abstract: The present invention provides combination therapy methods of treating proliferative diseases (such as cancer) comprising a first therapy comprising administering to an individual an effective amount of a taxane in a nanoparticle composition, and a second therapy which may include, for example, radiation, surgery, administration of chemotherapeutic agents, or combinations thereof. Also provided are methods of administering to an individual a drug taxane in a nanoparticle composition based on a metronomic dosing regime.
    Type: Grant
    Filed: July 20, 2007
    Date of Patent: August 24, 2010
    Assignee: Abraxis Bioscience, LLC
    Inventors: Neil P. Desai, Patrick Soon-Shiong, Tapas K. De
  • Process for the preparation of highly monodispersed polymeric hydrophilic nanoparticles
    Patent number: 5874111
    Abstract: Preparation of highly monodispersed polymeric hydrophilic nanoparticles having a size of up to 100 nm (in which may have drug substances encapsulated therein. The process comprises subjecting a mixture of an aqueous solution of a monomer or preformed polymer reverse micelles, a cross linking agent, initiator, and optionally, a drug or target substance to polymerization. The polymerized reaction product is dried for removal of solvent to obtain dried nanoparticles and surfactant employed in the process of preparing reverse micelles. The dry mass is dispersed in aqueous buffer and the surfactant and other toxic material are removed therefrom.
    Type: Grant
    Filed: January 7, 1997
    Date of Patent: February 23, 1999
    Inventors: Amarnath Maitra, Prashant Kumar Ghosh, Tapas K. De, Sanjeeb Kumar Sahoo