Patents by Inventor Tara deBoer

Tara deBoer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immobilized RNPs for sequence-specific nucleic acid capture and digital detection
    Patent number: 11905552
    Abstract: A digital biosensor for assaying a target nucleic acid and methods of using the biosensor for digitally detecting the target nucleic acid are disclosed wherein the biosensor includes a substrate having a substrate surface and at least two electrodes, a linker molecule having a first moiety conjugated to the substrate surface, a ribonucleoprotein (RNP) conjugated to a second moiety of the linker molecule, and a guide ribonucleic acid (gRNA) having a first sequence capable of binding to the inactive RNP and a second sequence capable of binding to the target nucleic acid.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: February 20, 2024
    Assignees: KECK GRADUATE INSTITUTE OF APPLIED LIFE SCIENCES, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Kiana Aran, Tara deBoer, Irina Conboy
  • Immobilized RNPs for sequence-specific nucleic acid capture and digital detection
    Publication number: 20190112643
    Abstract: A digital biosensor for assaying a target nucleic acid and methods of using the biosensor for digitally detecting the target nucleic acid are disclosed wherein the biosensor includes a substrate having a substrate surface and at least two electrodes, a linker molecule having a first moiety conjugated to the substrate surface, a ribonucleoprotein (RNP) conjugated to a second moiety of the linker molecule, and a guide ribonucleic acid (gRNA) having a first sequence capable of binding to the inactive RNP and a second sequence capable of binding to the target nucleic acid.
    Type: Application
    Filed: August 6, 2018
    Publication date: April 18, 2019
    Inventors: Kiana Aran, Tara deBoer, Irina Conboy