Patents by Inventor Tara K. SIGDEL

Tara K. SIGDEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunoprobe-based method to assess organ injury status through a biofluid-based cell-free DNA (cfDNA) assay
    Patent number: 11926868
    Abstract: This present disclosure provides methods and compositions that can be used to quantify cfDNA in biofluids using a hybridization approach.
    Type: Grant
    Filed: July 15, 2021
    Date of Patent: March 12, 2024
    Assignee: The Regents of the University of California
    Inventors: Minnie M. Sarwal, Tara K. Sigdel, Joshua Y. Yang
  • Methods of preparing a biofluid sample for detection of kidney injury
    Patent number: 11753680
    Abstract: Provided herein is the use of measurements of cell-free DNA, protein, and/or metabolite found in biofluid (e.g., urine) for identifying and treating organ injury. Provided herein are methods and compositions for monitoring, detecting, quantifying, and treating kidney injury in subjects suffering from or suspected of having an altered renal status by measuring amounts of cfDNA and one or more other markers, such as inflammation markers, apoptosis markers, protein, and DNA methylation.
    Type: Grant
    Filed: May 6, 2022
    Date of Patent: September 12, 2023
    Assignee: The Regents of the University of California
    Inventors: Minnie M. Sarwal, Tara K. Sigdel, Joshua Y. Yang
  • Reagents for detecting Alu elements in cell-free DNA (cfDNA)
    Patent number: 11505822
    Abstract: Provided herein is the use of measurements of cell-free DNA, protein, and/or metabolite found in biofluid (e.g., urine) for identifying and treating organ injury. Provided herein are methods and compositions for monitoring, detecting, quantifying, and treating kidney injury in subjects suffering from or suspected of having an altered renal status by measuring amounts of cfDNA and one or more other markers, such as inflammation markers, apoptosis markers, protein, and DNA methylation.
    Type: Grant
    Filed: October 11, 2021
    Date of Patent: November 22, 2022
    Assignee: The Regents of the University of California
    Inventors: Minnie M. Sarwal, Tara K. Sigdel, Joshua Y. Yang
  • REAGENTS FOR DETECTING ALU ELEMENTS IN CELL-FREE DNA (cfDNA)
    Publication number: 20220333182
    Abstract: Provided herein is the use of measurements of cell-free DNA, protein, and/or metabolite found in biofluid (e.g., urine) for identifying and treating organ injury. Provided herein are methods and compositions for monitoring, detecting, quantifying, and treating kidney injury in subjects suffering from or suspected of having an altered renal status by measuring amounts of cfDNA and one or more other markers, such as inflammation markers, apoptosis markers, protein, and DNA methylation.
    Type: Application
    Filed: May 6, 2022
    Publication date: October 20, 2022
    Applicant: The Regents of the University of California
    Inventors: Minnie M. Sarwal, Tara K. Sigdel, Joshua Y. Yang
  • REAGENTS FOR DETECTING ALU ELEMENTS IN CELL-FREE DNA (cfDNA)
    Publication number: 20220033892
    Abstract: Provided herein is the use of measurements of cell-free DNA, protein, and/or metabolite found in biofluid (e.g., urine) for identifying and treating organ injury. Provided herein are methods and compositions for monitoring, detecting, quantifying, and treating kidney injury in subjects suffering from or suspected of having an altered renal status by measuring amounts of cfDNA and one or more other markers, such as inflammation markers, apoptosis markers, protein, and DNA methylation.
    Type: Application
    Filed: October 11, 2021
    Publication date: February 3, 2022
    Inventors: Minnie M. Sarwal, Tara K. Sigdel, Joshua Y. Yang
  • A NOVEL IMMUNOPROBE-BASED METHOD TO ASSESS ORGAN INJURY STATUS THROUGH A BIOFLUID-BASED CELL-FREE DNA (CFDNA) ASSAY
    Publication number: 20210340610
    Abstract: This present disclosure provides methods and compositions that can be used to quantify cfDNA in biofluids using a hybridization approach.
    Type: Application
    Filed: July 15, 2021
    Publication date: November 4, 2021
    Inventors: Minnie M. Sarwal, Tara K. Sigdel, Joshua Y. Yang
  • Immunoprobe-based method to assess organ injury status through a biofluid-based cell-free DNA (CFDNA) assay
    Patent number: 11124824
    Abstract: This present disclosure provides methods and compositions that can be used to quantify cfDNA in biofluids using a hybridization approach.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: September 21, 2021
    Assignee: The Regents of the University of California
    Inventors: Minnie M. Sarwal, Tara K. Sigdel, Joshua Y. Yang
  • Immunoprobe-based method to assess organ injury status through a biofluid-based cell-free DNA (CFDNA) assay
    Patent number: 10995368
    Abstract: Provided herein is the use of measurements of cell-free DNA, protein, and/or metabolite found in biofluid (e.g., urine) for identifying and treating organ injury. Provided herein are methods and compositions for monitoring, detecting, quantifying, and treating kidney injury in subjects suffering from or suspected of having an altered renal status by measuring amounts of cfDNA and one or more other markers, such as inflammation markers, apoptosis markers, protein, and DNA methylation.
    Type: Grant
    Filed: October 7, 2020
    Date of Patent: May 4, 2021
    Assignee: The Regents of the University of California
    Inventors: Minnie M. Sarwal, Tara K. Sigdel, Joshua Y. Yang
  • Immunoprobe-based method to assess organ injury status through a biofluid-based cell-free DNA (cfDNA) assay
    Patent number: 10982272
    Abstract: This application relates to the use of measurements of cell-free DNA, protein, and/or metabolite found in biofluid (e.g., urine) for identifying and treating organ injury. The application includes methods and compositions for monitoring, detecting, quantifying, and treating kidney injury in subjects suffering from or suspected of having an altered renal status by measuring amounts of cfDNA and one or more other markers, such as inflammation markers, apoptosis markers, protein, and DNA methylation.
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: April 20, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Minnie M. Sarwal, Tara K. Sigdel, Joshua Y. Yang
  • NOVEL IMMUNOPROBE-BASED METHOD TO ASSESS ORGAN INJURY STATUS THROUGH A BIOFLUID-BASED CELL-FREE DNA (CFDNA) ASSAY
    Publication number: 20210024988
    Abstract: This application relates to the use of measurements of cell-free DNA, protein, and/or metabolite found in biofluid (e.g., urine) for identifying and treating organ injury. The application includes methods and compositions for monitoring, detecting, quantifying, and treating kidney injury in subjects suffering from or suspected of having an altered renal status by measuring amounts of cfDNA and one or more other markers, such as inflammation markers, apoptosis markers, protein, and DNA methylation.
    Type: Application
    Filed: October 7, 2020
    Publication date: January 28, 2021
    Inventors: Minnie M. Sarwal, Tara K. Sigdel, Joshua Y. Yang
  • NOVEL IMMUNOPROBE-BASED METHOD TO ASSESS ORGAN INJURY STATUS THROUGH A BIOFLUID-BASED CELL-FREE DNA (CFDNA) ASSAY
    Publication number: 20200032331
    Abstract: This present disclosure provides methods and compositions that can be used to quantify cfDNA in biofluids using a hybridization approach.
    Type: Application
    Filed: October 9, 2019
    Publication date: January 30, 2020
    Inventors: Minnie M. SARWAL, Tara K. Sigdel, Joshua Y. Yang
  • NOVEL IMMUNOPROBE-BASED METHOD TO ASSESS ORGAN INJURY STATUS THROUGH A BIOFLUID-BASED CELL-FREE DNA (CFDNA) ASSAY
    Publication number: 20190211385
    Abstract: This present disclosure provides methods and compositions that can be used to quantify cfDNA in biofluids using a hybridization approach.
    Type: Application
    Filed: August 17, 2017
    Publication date: July 11, 2019
    Inventors: Minnie M. SARWAL, Tara K. SIGDEL, Joshua Y. YANG