Patents by Inventor Tarek ABDELJAWAD

Tarek ABDELJAWAD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12312576
    Abstract: A system for delivering a payload to a cell that includes: a platform supporting an input container, an output container, and a receiver for receiving all or part of a disposable assembly, the disposable assembly including a preparation vessel and a constriction cartridge. The preparation vessel holds a cell suspension as it is prepared for passage through one or more cell-deforming constrictions, and the constriction cartridge houses a component that includes the one or more cell deforming constrictions. Passage through the cell-deforming constrictions causes perturbations in cell membranes to allow entry of a payload into the cells. The system includes one or more processors configured to receive input from a user and to automatically control pressure, temperature, agitation, and/or flow of the cell suspension as it passes through the input container, through the preparation vessel, through the constriction cartridge, and to the output container.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: May 27, 2025
    Assignee: STEMCELL TECHNOLOGIES CANADA INC.
    Inventors: Maisam Dadgar, Tarek Abdeljawad, Howard Bernstein
  • Publication number: 20250115854
    Abstract: A system for delivering a payload to a cell that includes: a platform supporting an input container, an output container, and a receiver for receiving all or part of a disposable assembly, the disposable assembly including a preparation vessel and a constriction cartridge. The preparation vessel holds a cell suspension as it is prepared for passage through one or more cell-deforming constrictions, and the constriction cartridge houses a component that includes the one or more cell deforming constrictions. Passage through the cell-deforming constrictions causes perturbations in cell membranes to allow entry of a payload into the cells. The system includes one or more processors configured to receive input from a user and to automatically control pressure, temperature, agitation, and/or flow of the cell suspension as it passes through the input container, through the preparation vessel, through the constriction cartridge, and to the output container.
    Type: Application
    Filed: December 17, 2024
    Publication date: April 10, 2025
    Inventors: Maisam DADGAR, Tarek ABDELJAWAD, Howard BERNSTEIN
  • Patent number: 12150982
    Abstract: The present application provides formulations of modified peripheral blood mononuclear cells (PBMCs), wherein the formulation comprises: PBMCs comprising at least one antigen (e.g., a human papillomavirus (HPV) antigen) and a cryopreservation medium. In some embodiments, the PBMCs are conditioned by incubating the PBMC in the presence of an adjuvant.
    Type: Grant
    Filed: December 28, 2021
    Date of Patent: November 26, 2024
    Assignee: STEMCELL TECHNOLOGIES CANADA INC.
    Inventors: Howard Bernstein, Scott Loughhead, Matthew Booty, Kelan Hlavaty, Tarek Abdeljawad, Maisam Dadgar, Jason Murray, David Chirgwin, Harry An, Armon R. Sharei
  • Publication number: 20220241392
    Abstract: The present application provides formulations of modified peripheral blood mononuclear cells (PBMCs), wherein the formulation comprises: PBMCs comprising at least one antigen (e.g., a human papillomavirus (HPV) antigen) and a cryopreservation medium. In some embodiments, the PBMCs are conditioned by incubating the PBMC in the presence of an adjuvant.
    Type: Application
    Filed: December 28, 2021
    Publication date: August 4, 2022
    Inventors: Howard BERNSTEIN, Scott LOUGHHEAD, Matthew BOOTY, Kelan HLAVATY, Tarek ABDELJAWAD, Maisam DADGAR, Jason MURRAY, David CHIRGWIN, Harry AN, Armon R. SHAREI
  • Publication number: 20220233676
    Abstract: The present application provides formulations of activating antigen carriers (AACs), wherein the formulation comprises: AACs comprise at least one antigen and an adjuvant and a cryopreservation medium.
    Type: Application
    Filed: December 28, 2021
    Publication date: July 28, 2022
    Inventors: Howard BERNSTEIN, Defne YARAR, Katarina BLAGOVIC, Amritha RAMAKRISHNAN, Maisam DADGAR, Louise CLEAR, Jason MURRAY, Tarek ABDELJAWAD, Claire PAGE
  • Publication number: 20210363479
    Abstract: The present disclosure generally relates to a systems and methods for processing cells, and kits for use with such methods and processes. In some aspects, the system, methods, and processes can be used to produce cell therapeutics.
    Type: Application
    Filed: May 21, 2021
    Publication date: November 25, 2021
    Inventors: Maisam DADGAR, Tarek ABDELJAWAD, Howard BERNSTEIN
  • Publication number: 20200332243
    Abstract: A system for delivering a payload to a cell that includes: a platform supporting an input container, an output container, and a receiver for receiving all or part of a disposable assembly, the disposable assembly including a preparation vessel and a constriction cartridge. The preparation vessel holds a cell suspension as it is prepared for passage through one or more cell-deforming constrictions, and the constriction cartridge houses a component that includes the one or more cell deforming constrictions. Passage through the cell-deforming constrictions causes perturbations in cell membranes to allow entry of a payload into the cells. The system includes one or more processors configured to receive input from a user and to automatically control pressure, temperature, agitation, and/or flow of the cell suspension as it passes through the input container, through the preparation vessel, through the constriction cartridge, and to the output container.
    Type: Application
    Filed: December 18, 2018
    Publication date: October 22, 2020
    Inventors: Maisam DADGAR, Tarek ABDELJAWAD, Howard BERNSTEIN