Abstract: The distal portion of a tissue-penetrating device includes a structure to guide a closure device associated with closing the tissue layer while the device remains in position, prior to removal of the device. The proximal portion of the device includes a visual and/or tactile indication corresponding to the guide structure. The guide structure may include a plurality of passageways such as slits or gaps to pass a suture, for example. The device may assume the shape of a conventional cylindrical cannula having inner and outer diameters defining a cylindrical wall, in which case the guide structure may include a plurality of passageways in the wall. The cannula may have any gauge associated with any surgical procedure, including procedures involving large wounds or incisions, and microsurgical procedures involving minute punctures, including vitrectomies.

Abstract: A membrane aggregating forceps may include a blank, a membrane aggregating forceps tip of the blank, a hypodermic tube, and an actuation structure. The blank may be disposed in the hypodermic tube and the actuation structure wherein a compression of the actuation structure is configured to close the membrane aggregating forceps tip and wherein a decompression of the actuation structure is configured to open the membrane aggregating forceps tip. The membrane aggregating forceps tip may include a first membrane aggregating forceps jaw having a first curved medial projection and a second membrane aggregating forceps jaw having a second curved medial projection. The first curved medial projection may include a first membrane socket, a first membrane aggregating fillet, and a first blunt edge. The second curved medial projection may include a second membrane socket, a second membrane aggregating filled, and a second blunt edge.

Abstract: A membrane aggregating forceps may include a blank, a membrane aggregating forceps tip of the blank, a hypodermic tube, and an actuation structure. The blank may be disposed in the hypodermic tube and the actuation structure wherein a compression of the actuation structure is configured to close the membrane aggregating forceps tip and wherein a decompression of the actuation structure is configured to open the membrane aggregating forceps tip. The membrane aggregating forceps tip may include a first membrane aggregating forceps jaw having a first curved medial projection and a second membrane aggregating forceps jaw having a second curved medial projection. The first curved medial projection may include a first membrane socket, a first membrane aggregating fillet, and a first blunt edge. The second curved medial projection may include a second membrane socket, a second membrane aggregating filled, and a second blunt edge.