Patents by Inventor Tarek Suhayl

Tarek Suhayl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION
    Publication number: 20090291971
    Abstract: The present invention relates to processes for the preparation of heteroaryl ethers. In some embodiments, the processes relate to cross coupling reactions between triazol-1-yloxy and triazol-1-yl heterocycles with aryl boronic acids. In a further aspect, this invention also relates to compounds that are useful for the treatment of oncological diseases or disorders, and for the treatment of inflammation.
    Type: Application
    Filed: October 30, 2008
    Publication date: November 26, 2009
    Applicant: Wyeth
    Inventors: Tarek Suhayl Mansour, Sumrit Wacharasindhu, Zhao-Kui Wan, Sujata Bardhan
  • 2-Aryl- and 2-Heteroarylthiazolyl Compounds, Methods for Their Preparation and Use Thereof
    Publication number: 20090270363
    Abstract: The present invention discloses fused bicyclic 2-aryl- or 2-heteroarylthiazolyl compounds and their pharmaceutically acceptable salts and esters thereof, which are useful for inhibiting the growth of cancerous cells, inhibiting human breast carcinoma tumor growth in particular and to treat diseases or disorders associated with securin, including elevated securin levels.
    Type: Application
    Filed: March 27, 2009
    Publication date: October 29, 2009
    Applicant: Wyeth
    Inventors: Nan Zhang, Semiramis Ayral-Kaloustian, Tarek Suhayl Mansour, Thai Hiep Nguyen, Chuansheng Niu, Edward Christian Rosfjord, Ronald Suayan, Hwei-Ru Tsou
  • [a]-FUSED INDOLE COMPOUNDS, THEIR USE AS mTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES
    Publication number: 20090192147
    Abstract: The invention relates to [a]-fused indole compounds of the Formula II, or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein. The invention also relates to compositions comprising the compounds of Formula II, and methods for making and using the compounds.
    Type: Application
    Filed: January 30, 2009
    Publication date: July 30, 2009
    Applicant: Wyeth
    Inventors: Semiramis Ayral-Kaloustian, Nan Zhang, Aranapakam Mudumbai Venkatesan, Tarek Suhayl Mansour, Thai Hiep Nguyen, James Thomas Anderson
  • Glutamate aggrecanase inhibitors
    Patent number: 7553873
    Abstract: The present invention relates to modulators of metalloproteinase activity.
    Type: Grant
    Filed: July 11, 2006
    Date of Patent: June 30, 2009
    Assignee: Wyeth
    Inventors: Phaik-Eng Sum, Jerauld Stanley Skotnicki, Steve Yik-Kai Tam, Tarek Suhayl Mansour, David Brian How, Joshua James Sabatini, Jason Shaoyun Xiang, Eric Feyfant
  • Processes For Preparing Bicyclic Oxazine Carboxaldehyde and Beta-Lactamase Inhibitors
    Publication number: 20090018332
    Abstract: The invention relates to processes for the preparation of the bicyclic oxazine carboxaldehyde Compound 1: The invention also relates to the use of Compound 1 in the preparation of ?-lactamase inhibitors.
    Type: Application
    Filed: June 24, 2008
    Publication date: January 15, 2009
    Applicant: Wyeth
    Inventors: Kenneth Alfred Martin Kremer, Lalitha Krishnan, Aranapakam Mudumbai Venkatesan, Mellard Norman Jennings, Joseph Zeldis, Takao Abe, Tarek Suhayl Mansour, Henry Lee Strong
  • Tricyclic 6-Alkylidene-Penems as Beta-Lactamase Inhibitors
    Publication number: 20080318921
    Abstract: The present invention provides a compound of formula I, pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need thereof.
    Type: Application
    Filed: August 7, 2008
    Publication date: December 25, 2008
    Applicant: Wyeth
    Inventors: Aranapakam Mudumbai Venkatesan, Tarek Suhayl Mansour, Takao Abe, Ado Mihira, Atul Agarwal, Hideki Ushirogochi, Yansong Gu, Satoshi Tamai, Fuk-Wah Sum
  • Bicyclic 6-Alkylidene-Penems as Beta-Lactamase Inhibitors
    Publication number: 20080312203
    Abstract: The present invention provides a compound of formula I wherein one of A and B is hydrogen and the other an optionally substituted fused bicyclic heteroaryl group; and X is O, pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need thereof.
    Type: Application
    Filed: August 21, 2008
    Publication date: December 18, 2008
    Applicant: Wyeth
    Inventors: Aranapakam Mudumbai Venkatesan, Tarek Suhayl Mansour, Takao Abe, Itsuki Yamamura, Tsuyoshi Takasaki, Atul Agarwal, Osvaldo Dos Santos, Fuk-Wah Sum, Yang-I Lin
  • 4-substituted or unsubstituted-7-hydro-1,4-thiazepine-7-[bicyclic or tricyclic heteroaryl] substituted-3,6-dicarboxylic acid derivatives as ?-lactamase inhibitors
    Patent number: 7229983
    Abstract: The present invention relates to novel, low molecular weight broad spectrum compounds in particular to a class of 4-substituted or unsubstituted-7-hydro-1,4-thiazepine-7-[bicyclic or tricyclic heteroaryl] substituted-3,6-dicarboxylic acid or their derivatives which have ?-lactamase inhibitory and antibacterial properties. The compounds are therefore useful in the treatment of antibacterial infections in humans or animals, either alone or in combination with other antibiotics.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: June 12, 2007
    Assignee: Wyeth Holdings Corporation
    Inventors: Tarek Suhayl Mansour, Aranapakam Mudumbai Venkatesan
  • Bicyclic 6-alkylidene-penems as ?-lactamase inhibitors
    Patent number: 7112582
    Abstract: The present invention provides a compound of formula I, pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need thereof. wherein one of A and B denotes hydrogen and the other an optionally substituted fused bicyclic heteroaryl group; and X is S.
    Type: Grant
    Filed: May 1, 2003
    Date of Patent: September 26, 2006
    Assignee: Wyeth
    Inventors: Aranapakam Mudumbai Venkatesan, Tarek Suhayl Mansour, Takao Abe, Itsuki Yamamura, Tsuyoshi Takasaki, Atul Agarwal, Osvaldo dos Santos, Fuk-Wah Sum, Yang-I Lin
  • Tricyclic 6-alkylidene-penems as ?-lactamase inhibitors
    Patent number: 7018997
    Abstract: The present invention provides a compound of formula I, pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need thereof. wherein one of A and B denotes hydrogen and the other an optionally substituted fused tricyclic heteroaryl group; and X is S.
    Type: Grant
    Filed: May 1, 2003
    Date of Patent: March 28, 2006
    Assignee: Wyeth
    Inventors: Aranapakam Mudumbai Venkatesan, Tarek Suhayl Mansour, Takao Abe, Ado Mihira, Atul Agarwal, Hideki Ushirogochi, Yansong Gu, Satoshi Tamai, Fuk-Wah Sum
  • 4-Substituted or unsubstituted-7-hydro-1,4-thiazepine-7-[bicyclic or tricyclic heteroaryl] substituted-3,6-dicarboxylic acid derivatives as beta-lactamase inhibitors
    Publication number: 20040214812
    Abstract: The present invention relates to novel, low molecular weight broad spectrum compounds in particular to a class of 4-substituted or unsubstituted-7-hydro-1,4-thiazepine-7-[bicyclic or tricyclic heteroaryl] substituted-3,6-dicarboxylic acid or their derivatives which have &bgr;-lactamase inhibitory and antibacterial properties. The compounds are therefore useful in the treatment of antibacterial infections in humans or animals, either alone or in combination with other antibiotics.
    Type: Application
    Filed: April 28, 2004
    Publication date: October 28, 2004
    Applicant: Wyeth Holdings Corporation
    Inventors: Tarek Suhayl Mansour, Aranapakam Mudumbai Venkatesan
  • Process for preparing 6-alkylidene penem derivatives
    Publication number: 20040132708
    Abstract: The present invention provides a process of making compounds of formula I, which are useful for the treatment of bacterial infection or disease.
    Type: Application
    Filed: October 24, 2003
    Publication date: July 8, 2004
    Applicant: Wyeth
    Inventors: Takao Abe, Hiroshi Matsunaga, Ado Mihira, Chisato Sato, Hideki Ushirogochi, Koichi Sato, Tsuyoshi Takasaki, Aranapakam Mudumbai Venkatesan, Tarek Suhayl Mansour
  • Bicyclic 5-alkylidene-penems as beta lactamases inhibitors
    Publication number: 20040077622
    Abstract: The present invention provides a compound of formula 1, pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need thereof.
    Type: Application
    Filed: May 1, 2003
    Publication date: April 22, 2004
    Applicant: Wyeth
    Inventors: Aranapakam Mudumbai Venkatesan, Tarek Suhayl Mansour, Takao Abe, Itsuki Yamamura, Tsuyoshi Takasaki, Atul Agarwal, Osvaldo dos Santos, Fuk-Wah Sum, Yang-I Lin
  • Process for preparing 6-alkylidene penem derivatives
    Publication number: 20040053913
    Abstract: The present invention provides a process of making compounds of formula I, which are useful for the treatment of bacterial infection or disease.
    Type: Application
    Filed: May 1, 2003
    Publication date: March 18, 2004
    Applicant: Wyeth
    Inventors: Takao Abe, Hiroshi Matsunaga, Ado Mihira, Chisato Sato, Hideki Ushirogochi, Koichi Sato, Tsuyoshi Takasaki, Aranapakam Mudumbai Venkatesan, Tarek Suhayl Mansour
  • Tricyclic 6-alkylidene-penems as beta-lactamase inhibitors
    Publication number: 20040043978
    Abstract: The present invention provides a compound of formula I, pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need thereof.
    Type: Application
    Filed: May 1, 2003
    Publication date: March 4, 2004
    Applicant: Wyeth
    Inventors: Aranapakam Mudumbai Venkatesan, Tarek Suhayl Mansour, Takao Abe, Ado Mihira, Atul Agarwal, Hideki Ushirogochi, Yansong Gu, Satoshi Tamai, Fuk-Wah Sum