Abstract: This invention is a stent to reduce blood flow to an aneurysm comprising: (a) an inner member, wherein this inner member is expanded from a first configuration to a second configuration within the parent vessel of an aneurysm, wherein the circumference of the second configuration is larger than the circumference of the first configuration; and (b) an outer member, wherein this outer member is less porous than the inner member, wherein this outer member covers or surrounds a first percentage of the surface area of the inner member when the inner structure is in the first configuration, wherein this outer member covers or surrounds a second percentage of the surface area of the inner member when the inner structure is in the second configuration, and wherein the second percentage less than the first percentage.

Abstract: A device to treat an aneurysm can include a plurality of soft and compressible fill members. A flow conduit can carry the fill members in a liquid flow. A flexible, expandable, and liquid-permeable net or mesh enclosure can be inserted into and to fit within the aneurysm. The net or mesh enclosure can receive and retain the plurality of fill members while openings in the net or mesh enclosure allow enough liquid flow through the net or mesh enclosure to transport the fill members into the net or mesh enclosure. A resulting accumulation of the plurality of fill members within the net or mesh enclosure causes the net or mesh enclosure to expand and to come into contact with and generally conform with an interior wall of the aneurysm. This can substantially occlude the aneurysm and retain the net or mesh enclosure within the aneurysm.

Abstract: This invention is a device and method for reducing blood flow into an aneurysm, especially a cerebral aneurysm, in order to promote therapeutic embolization of the aneurysm. The device comprises: at least one core member that is inserted into the aneurysm; and at least one longitudinal flexible member that is wound repeatedly around the core member within the aneurysm. The longitudinal flexible member is wound around the core member until the rotational accumulation of the flexible member reduces blood flow into the aneurysm and promotes therapeutic embolization of the aneurysm.

Abstract: This invention gives physicians in situ control to create differences in wall porosity between different areas of a stent wall. This enables a physician to customize the stent within a blood vessel to selectively block blood flow to an aneurysm with a low-porosity area of the stent wall, but allow blood flow to nearby branching vessels through one or more high-porosity areas of the stent wall. The method comprises inserting a stent into a blood vessel and, in situ, expanding the stent in a non-uniform manner, thereby causing one or more areas of the stent wall to have a lower post-expansion porosity than the rest of the stent wall. With this invention, physicians can selectively block blood flow into an aneurysm while maintaining blood flow into nearby branching vessels, even in tortuous and complex vessel configurations.

Abstract: This invention gives physicians in situ control to create differences in wall porosity between different areas of a stent wall. This enables a physician to customize the stent within a blood vessel to selectively block blood flow to an aneurysm with a low-porosity area of the stent wall, but allow blood flow to nearby branching vessels through one or more high-porosity areas of the stent wall. The method comprises inserting a stent into a blood vessel and, in situ, expanding the stent in a non-uniform manner, thereby causing one or more areas of the stent wall to have a lower post-expansion porosity than the rest of the stent wall. With this invention, physicians can selectively block blood flow into an aneurysm while maintaining blood flow into nearby branching vessels, even in tortuous and complex vessel configurations.

Abstract: This invention is an implantable device that is attached to the exterior of an aneurysm, or to the exterior of some other portion of a blood vessel wall, wherein this device elutes, or otherwise emits, an emitted substance to prevent or treat vasospasm. This device may be embodied as a magnesium-eluting aneurysm clip. A magnesium-eluting aneurysm clip not only stops blood from escaping out of the aneurysm, but it also helps to prevent vasospasm from any blood that has already escaped.

Abstract: This invention is a device for reducing blood flow into an aneurysm, especially a cerebral aneurysm, in order to promote therapeutic embolization of the aneurysm. The device comprises: at least one core member that is inserted into the aneurysm; and at least one longitudinal flexible member that is wound repeatedly around the core member within the aneurysm. The longitudinal flexible member is wound around the core member until the rotational accumulation of the flexible member reduces blood flow into the aneurysm and promotes therapeutic embolization of the aneurysm. This invention has key advantages over the prior art. In contrast to coiling, the longitudinal flexible members can fill a higher volume of the aneurysm because they do not have to be resilient and because mass accumulation starts at the center of the aneurysm rather than its perimeter. Higher fill volume can reduce the chances of continued aneurysm expansion or even rupture.

Abstract: A device to treat an aneurysm can include a plurality of soft and compressible fill members. A flow conduit can carry the fill members in a liquid flow. A flexible, expandable, and liquid-permeable net or mesh enclosure can be inserted into and to fit within the aneurysm. The net or mesh enclosure can receive and retain the plurality of fill members while openings in the net or mesh enclosure allow enough liquid flow through the net or mesh enclosure to transport the fill members into the net or mesh enclosure. A resulting accumulation of the plurality of fill members within the net or mesh enclosure causes the net or mesh enclosure to expand and to come into contact with and generally conform with an interior wall of the aneurysm. This can substantially occlude the aneurysm and retain the net or mesh enclosure within the aneurysm.

Abstract: This invention is a stent that is inserted into the parent vessel of an aneurysm in order to reduce blood flow to the aneurysm and promote embolization of the aneurysm. The stent wall includes an inner structure that can be expanded from a compressed state to a resilient expanded state and an outer flexible layer that covers all or part of the inner structure. Embolic members are placed and retained in the gap between the inner structure and the outer layer in the area of the aneurysm neck in order to reduce blood flow to the aneurysm.