Patents by Inventor Tarja Malm

Tarja Malm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PIEZO AGONISTS FOR PREVENTING OR REVERTING ABNORMAL AMYLOID DEPOSITION
    Publication number: 20220265646
    Abstract: The present invention relates to diagnosing, preventing, delaying or reverting the progression of pathologies associated with abnormal amyloid deposits, such as that exemplified by Alzheimer's disease (AD). More specifically, the method involves administration of specific molecules that function as Piezo agonists, such as Yoda1, Jedi1, 5 Jedi2, or functional analogs thereof, that are able to modulate microglial activation towards anti-inflammatory state and/or interfere with the formation of amyloidogenic peptides and/or increase their efflux from the central nervous system.
    Type: Application
    Filed: July 7, 2020
    Publication date: August 25, 2022
    Applicant: ITÄ-SUOMEN YLIOPISTO
    Inventors: Tarja MALM, Rashid GINIATULLIN
  • IL-33 and treatment of neurodegenerative diseases
    Patent number: 9867867
    Abstract: The present invention relates to the fields of life sciences and medicine. Specifically, the invention relates to therapies of neurodegenerative diseases. More specifically, the present invention relates to interleukin-33 (IL-33), a fragment thereof, a polynucleotide encoding IL-33 or a fragment thereof for use in treatment or prevention of a neurodegenerative disease involving inflammation in a subject and to a method of treating or preventing a neurodegenerative disease involving neuroinflammation in a subject. Still, the present invention relates to IL-33, a fragment thereof, a polynucleotide encoding IL-33 or a fragment thereof for use in improving or restoring neuronal function or endogenous neuronal repair mechanisms, or enhancing endogenous neurogenesis, oligodendrogenesis or neuronal differentiation in a subject.
    Type: Grant
    Filed: February 21, 2014
    Date of Patent: January 16, 2018
    Assignee: MAGIC EPOCH HOLDINGS LIMITED
    Inventors: Jari Koistinaho, Tarja Malm, Eveliina Pollari, Katja Kanninen
  • IL-33 and Treatment of Neurodegenerative Diseases
    Publication number: 20160000876
    Abstract: The present invention relates to the fields of life sciences and medicine. Specifically, the invention relates to therapies of neurodegenerative diseases. More specifically, the present invention relates to interleukin-33 (IL-33), a fragment thereof, a polynucleotide encoding IL-33 or a fragment thereof for use in treatment or prevention of a neurodegenerative disease involving inflammation in a subject and to a method of treating or preventing a neurodegenerative disease involving neuroinflammation in a subject. Still, the present invention relates to IL-33, a fragment thereof, a polynucleotide encoding IL-33 or a fragment thereof for use in improving or restoring neuronal function or endogenous neuronal repair mechanisms, or enhancing endogenous neurogenesis, oligodendrogenesis or neuronal differentiation in a subject.
    Type: Application
    Filed: February 21, 2014
    Publication date: January 7, 2016
    Inventors: Jari Koistinaho, Tarja Malm, Eveliina Pollari, Katja Kanninen