Patents by Inventor Tarlochan Singh Dhadialla

Tarlochan Singh Dhadialla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
    Publication number: 20010044151
    Abstract: This invention relates to an improved method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene. The improvement resides in a select group of non-steroid ligands which show improved activity over known ligands.
    Type: Application
    Filed: April 12, 2001
    Publication date: November 22, 2001
    Inventors: Glenn Richard Carlson, Dean Ervin Cress, Tarlochan Singh Dhadialla, Robert Eugene Hormann, Dat Phat Le
  • Ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
    Patent number: 6258603
    Abstract: This invention relates to an improved method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene. The improvement resides in a select group of non-steroid ligands which show improved activity over known ligands.
    Type: Grant
    Filed: May 20, 1999
    Date of Patent: July 10, 2001
    Assignee: Rohm and Haas Company
    Inventors: Glenn Richard Carlson, Dean Ervin Cress, Tarlochan Singh Dhadialla, Robert Eugene Hormann, Dat Phat Le