Patents by Inventor Taro Aoki
Taro Aoki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7776881Abstract: A hypertriglyceridemia therapeutic agent made up of a synergistically effective blood-triglyceride decreasing amount of a combination of a pitavastatin and eicosapentaenoic acid (EPA), or an ester thereof.Type: GrantFiled: December 5, 2005Date of Patent: August 17, 2010Assignees: Kowa Co., Ltd., Nissan Chemical Industries, Ltd.Inventors: Taro Aoki, Junji Yamaguchi, Yusuke Sasaki
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Publication number: 20100173938Abstract: The present invention provides a medicament exhibiting an excellent nerve cell death inhibitory action. The present invention relates to a nerve cell death inhibitor comprising a pitavastatin and donepezil or a salt thereof in combination.Type: ApplicationFiled: October 2, 2008Publication date: July 8, 2010Applicant: KOWA COMPANY, LTD.Inventors: Fumiyasu Sato, Yasunobu Yoshinaka, Taro Aoki
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Patent number: 7750019Abstract: A compound represented by the following general formula (I) or a salt thereof, or a solvate thereof: (wherein R1, R2, R3, R4 and R5 are the same or different, and represent hydrogen atom, a halogen atom, a lower alkyl group etc., R6, R7 and R8 are the same or different, and represent hydrogen atom, a halogen atom, a lower alkyl group etc., R9 and R10 are the same or different, and represent hydrogen atom, a lower alkyl group, a (lower cycloalkyl)(lower alkyl) group etc., and R11 represents hydrogen atom, a halogen atom, a lower alkoxy group, a (lower alkyl)thio(lower alkoxy) group, a (lower alkyl)sulfinyl(lower alkoxy) group, a (lower alkyl)sulfonyl(lower alkoxy) group etc.), which has potent inhibitory activity on CETP.Type: GrantFiled: August 7, 2007Date of Patent: July 6, 2010Assignee: Kowa Company, Ltd.Inventors: Tadaaki Ohgiya, Toru Miura, Ayumu Okuda, Toshiharu Arai, Koichi Yamazaki, Taro Aoki, Katsutoshi Miyosawa, Haruki Shibata, Kimiyuki Shibuya
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Patent number: 7692328Abstract: The present invention provides a power unit of an underwater vehicle, which allows reduction in size and weight of a transformer for stepping down a power voltage of a power supply to increase a loading amount of a variety of devices with respect to the underwater vehicle, so as to obtain a favorable operating environment. The power unit is connected to the power supply through a cable and receives power through the cable. Further, the power unit comprises an electronic transformer having: a rectifier for rectifying a high-voltage alternate current power of the power supply into a direct current; a high-frequency converter for converting an output of the rectifier into a high-frequency alternate current; a transformer for stepping down an output voltage of the high-frequency converter; a rectifier for rectifying an output of the transformer into a direct current; and a control circuit for controlling the high-frequency converter.Type: GrantFiled: June 28, 2007Date of Patent: April 6, 2010Assignee: Japan Agency for Marine-Earth Science and TechnologyInventors: Hiroshi Yoshida, Taro Aoki, Fumihiko Endo, Takayoshi Watanabe, Katsuki Fujimoto, Osamu Numamoto
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Patent number: 7659271Abstract: A compound represented by the following general formula (I), wherein R1, R2, R3, R4 and R5 represent hydrogen atom, a halo(lower alkyl) group, cyano group and the like, R6 represents an alkyl group, a cycloalkyl group and the like, R7, R8, R9 and R10 represent hydrogen atom, a halogen atom, a lower alkyl group, a halo(lower alkyl) group and the like, R11 and R12 represent hydrogen atom, a lower alkyl group, a (lower cycloalkyl) (lower alkyl) group and the like, and R13 represents hydrogen atom, a halogen atom, a lower alkoxy group and the like, which has potent inhibitory activity on cholesterol ester transfer protein (CETP).Type: GrantFiled: April 10, 2008Date of Patent: February 9, 2010Assignee: Kowa Company, Ltd.Inventors: Tadaaki Ohgiya, Toru Miura, Ayumu Okuda, Toshiharu Arai, Koichi Yamazaki, Taro Aoki, Katsutoshi Miyosawa, Haruki Shibata, Kimiyuki Shibuya
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Publication number: 20090291980Abstract: The present invention is directed to a triglyceride-lowering agent, exhibiting excellent triglyceride-lowering effect and a hyperinsulinemia-ameliorating agent. The triglyceride-lowering agent and hyperinsulinemia-ameliorating agent are characterized by containing a pitavastatin compound, and amlodipine or a salt thereof.Type: ApplicationFiled: March 28, 2007Publication date: November 26, 2009Applicants: Nissan Chemical Industries Ltd., Kowa Co., Ltd.Inventors: Toru Yokoyama, Taro Aoki
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Patent number: 7598233Abstract: This invention relates to a method for treating thrombosis by combined administration of a pitavastatin with aspirin.Type: GrantFiled: June 22, 2005Date of Patent: October 6, 2009Assignees: Kowa Co., Ltd., Nissan Chemical Industries, Ltd.Inventors: Toru Yokoyama, Taro Aoki
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Publication number: 20090227610Abstract: The present invention relates to hypotriglyceridemic agent containing HMG-CoA reductase inhibitor and cAMP protease inhibitor.Type: ApplicationFiled: May 25, 2006Publication date: September 10, 2009Applicant: KOWA COMPANY, LTD.Inventors: Toru Yokoyama, Taro Aoki
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Publication number: 20090082352Abstract: A compound represented by the following general formula (I), wherein R1, R2, R3, R4 and R5 represent hydrogen atom, a halo(lower alkyl) group, cyano group and the like, R6 represents an alkyl group, a cycloalkyl group and the like, R7, R8, R9 and R10 represent hydrogen atom, a halogen atom, a lower alkyl group, a halo(lower alkyl) group and the like, R11 and R12 represent hydrogen atom, a lower alkyl group, a (lower cycloalkyl) (lower alkyl) group and the like, and R13 represents hydrogen atom, a halogen atom, a lower alkoxy group and the like, which has potent inhibitory activity on cholesterol ester transfer protein (CETP).Type: ApplicationFiled: April 10, 2008Publication date: March 26, 2009Applicant: KOWA COMPANY, LTD.Inventors: Tadaaki OHGIYA, Toru MIURA, Ayumu OKUDA, Toshiharu ARAI, Koichi YAMAZAKI, Taro AOKI, Katsutoshi MIYOSAWA, Haruki SHIBATA, Kimiyuki SHIBUYA
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Publication number: 20090062306Abstract: A compound represented by the following general formula (I), wherein R1, R2, R3, R4 and R5 represent hydrogen atom, a halogen atom, a lower alkyl group and the like, R6 represents an alkyl group, a cycloalkyl group and the like, R7 and R8 represent hydrogen atom, a lower alkyl group, a (lower cycloalkyl)(lower alkyl) group and the like, R9 represents hydrogen atom, a halogen atom, a lower alkoxy group and the like, R10 and R11 represent hydrogen atom, a lower alkyl group, a lower alkoxy group, a halo(lower alkyl) group and the like, and A represents a heterocyclic ring constituted by 6 to 10 atoms, which has potent inhibitory activity on cholesterol ester transfer protein (CETP).Type: ApplicationFiled: March 11, 2008Publication date: March 5, 2009Applicant: KOWA COMPANY, LTD.Inventors: Tadaaki OHGIYA, Toru MIURA, Ayumu OKUDA, Toshiharu ARAI, Koichi YAMAZAKI, Taro AOKI, Katsutoshi MIYOSAWA, Haruki SHIBATA, Kimiyuki SHIBUYA
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Publication number: 20090054474Abstract: A compound represented by the following general formula (I) or a salt thereof, or a solvate thereof: (wherein R1, R2, R3, R4 and R5 are the same or different, and represent hydrogen atom, a halogen atom, a lower alkyl group etc., R6, R7 and R8 are the same or different, and represent hydrogen atom, a halogen atom, a lower alkyl group etc., R9 and R10 are the same or different, and represent hydrogen atom, a lower alkyl group, a (lower cycloalkyl)(lower alkyl) group etc., and R11 represents hydrogen atom, a halogen atom, a lower alkoxy group, a (lower alkyl)thio(lower alkoxy) group, a (lower alkyl)sulfinyl(lower alkoxy) group, a (lower alkyl)sulfonyl(lower alkoxy) group etc.), which has potent inhibitory activity on CETP.Type: ApplicationFiled: August 7, 2007Publication date: February 26, 2009Applicant: Kowa Company, Ltd.Inventors: Tadaaki OHGIYA, Toru MIURA, Ayumu OKUDA, Toshiharu ARAI, Koichi YAMAZAKI, Taro AOKI, Katsutoshi MIYOSAWA, Haruki SHIBATA, Kimiyuki SHIBUYA
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Publication number: 20090001810Abstract: The present invention provides a power unit of an underwater vehicle, which allows reduction in size and weight of a transformer for stepping down a power voltage of a power supply to increase a loading amount of a variety of devices with respect to the underwater vehicle, so as to obtain a favorable operating environment. The power unit is connected to the power supply through a cable and receives power through the cable. Further, the power unit comprises an electronic transformer having: a rectifier for rectifying a high-voltage alternate current power of the power supply into a direct current; a high-frequency converter for converting an output of the rectifier into a high-frequency alternate current; a transformer for stepping down an output voltage of the high-frequency converter; a rectifier for rectifying an output of the transformer into a direct current; and a control circuit for controlling the high-frequency converter.Type: ApplicationFiled: June 28, 2007Publication date: January 1, 2009Applicant: Japan Agency for Marine-Earth Science and TechnologyInventors: Hiroshi YOSHIDA, Taro Aoki, Fumihiko Endo, Takayoshi Watanabe, Katsuki Fujimoto, Osamu Numamoto
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Publication number: 20080305369Abstract: There is a problem in that a gas pressure in an oxygen container of an oxygen supply device is high, thereby causing a mounting cost for charging gas into the oxygen container. Further, there is also a problem in terms of safety at a time of operation.Type: ApplicationFiled: February 7, 2006Publication date: December 11, 2008Inventors: Tatsuya Muraki, Katuhiro Terao, Tetsunari Nakamura, Taro Aoki, Tadahiro Hyakudome, Syojiro Ishibashi
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Patent number: 7459447Abstract: Provided is a method for treating hyperlipidemia or hypercholesterolemia, which comprises administering effective doses of ezetimibe and pitavastatin or a salt or lactone derivative thereof.Type: GrantFiled: October 12, 2006Date of Patent: December 2, 2008Assignees: Kowa Co., Ltd., Nissan Chemical Industries, Ltd.Inventors: Taro Aoki, Hiroyuki Yamazaki, Takashi Maejima
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Publication number: 20080090518Abstract: The present invention provides a communication device and a communication method of an underwater vehicle, which use an electromagnetic field (electromagnetic wave), having a higher propagation speed than that of an acoustic wave, for communication between an underwater vehicle and a mother vessel or the like so as to allow real-time control of the underwater vehicle and the like and further to make the communication little sensitive to noise and the like. The communication device performs wireless communication between an underwater vehicle in water and an object on land or on water, and is configured to compress data to be transmitted and transmit/receive the compressed data by the use of a low-frequency electromagnetic field.Type: ApplicationFiled: October 11, 2006Publication date: April 17, 2008Applicant: JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECHNOLOGYInventors: Hiroshi Yoshida, Taro Aoki, Katsuki Fujimoto, Osamu Numamoto
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Publication number: 20080045567Abstract: A therapeutic agent for hyperlipidemia, diabetes, or hypertriglyceridemia containing an HMG-COA reductase inhibitor and a carboxylic acid compound represented by the following formula (1) or a salt thereof as effective ingredients. The therapeutic agent of the present invention has excellent effects of lowering blood cholesterol and blood triglycerides and is particularly useful for treatment of type IIb and type IV hyperlipidemia and treatment of diabetes and also useful for treatment of hypertriglyceridemia.Type: ApplicationFiled: May 27, 2005Publication date: February 21, 2008Applicant: Kowa Co., LtdInventors: Taro Aoki, Junji Yamaguchi, Yusuke Sasaki
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Publication number: 20070179194Abstract: The present invention provides a method for treatment of diabetes, comprising administering a pitavastatin, and in combination therewith, enalapril or a salt thereof.Type: ApplicationFiled: June 29, 2006Publication date: August 2, 2007Applicants: Kowa Co., Ltd., Nissan Chemical Industries, Ltd.Inventors: Taro Aoki, Katsutoshi Miyosawa
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Publication number: 20070032467Abstract: Provided is a method for treating hyperlipidemia or hypercholesterolemia, which comprises administering effective doses of ezetimibe and pitavastatin or a salt or lactone derivative thereof.Type: ApplicationFiled: October 12, 2006Publication date: February 8, 2007Applicants: KOWA CO., LTD., Nisssan Chemical Industries, Ltd.Inventors: Taro Aoki, Hiroyuki Yamazaki, Takashi Maejima
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Publication number: 20060217352Abstract: This invention relates to a method for treating thrombosis by combined administration of a pitavastatin with aspirin.Type: ApplicationFiled: June 22, 2005Publication date: September 28, 2006Applicants: Kowa Co., Ltd., Nissan Chemical Industries, Ltd.Inventors: Toru Yokoyama, Taro Aoki
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Publication number: 20060111437Abstract: The present invention relates to a hyperlipemia therapeutic agent comprising pitavastatins and eicosapentaenoic acid or an ester derivative thereof as effective ingredients. According to the present invention, a type IIb and type IV hyperlipemia therapeutic agent having an excellent effect of lowering the cholesterol and triglyceride in blood is provided.Type: ApplicationFiled: December 5, 2005Publication date: May 25, 2006Applicants: Kowa Co., Ltd., NISSAN CHEMICAL INDUSTRIES, LTD.Inventors: Taro Aoki, Junji Yamaguchi, Yusuke Sasaki