Abstract: A fluid device includes a substrate and a gas-liquid separating filter, the substrate has a flow path through which a solution flows, a reservoir, in which the solution is accommodated, connected to the flow path, an injection hole configured to connect the reservoir to the outside, and an air introduction hole branched off from the injection hole and connected to the outside, and the gas-liquid separating filter is disposed in a path of the air introduction hole, allows passage of a gas flowing through the air introduction hole, and prevents passage of a liquid flowing through the air introduction hole.

Abstract: A wear debris collection device includes a rotation body that is connected to a rotation shaft and performs rotating movement in accordance with rotation of the rotation shaft, a braking member that brakes the rotating movement of the rotation body, a hood covering the rotation body and the braking member and to prevent dust from entering from outside, a blower that blows air into the hood, a collection apparatus that suctions air in the hood and collects wear debris of the braking member contained in the air, and an air pressure adjuster that measures air pressure in the hood and external air pressure and adjusts an air quantity of at least one of the blower and the collection apparatus so that the air pressure in the hood equals the external air pressure.

Abstract: The present invention aims at providing a fluidic device that can hold a large amount of solutions in a reservoir without depending on an attitude. The reservoir includes a meandering flow path including: a plurality of first flow paths that extend linearly along a first direction and that are arranged to be spaced in a second direction crossing the first direction; and a second flow path that extends linearly along the second direction such that a connection between first end sides of the adjacent first flow paths and a connection between second end sides of the adjacent first flow paths are alternately switched along the second direction for each first flow path, wherein the meandering flow path meanders along the second direction.

Abstract: A fluidic device includes a first circulation flow path and a second circulation flow path which circulate a solution containing a sample material, the first circulation flow path and the second circulation flow path share at least a part of the flow path, and at least one selected from the group consisting of a capture unit which captures the sample material, a detection unit which detects the sample material, a valve, and a pump is provided on the shared flow path.

Abstract: A fluid device includes a substrate which has a pair of substrate plates stacked in a thickness direction thereof, wherein the substrate is provided with a flow path which is formed by covering a groove portion provided in one substrate plate of the pair of substrate plates with the other substrate plate, wherein the flow path includes a merging portion, and a supply flow path, a discharge flow path, and a branch flow path which extend radially from the merging portion, wherein a discharge valve is provided between the merging portion and the discharge flow path, wherein a branch valve is provided between the merging portion and the branch flow path, wherein the merging portion is filled with a solution by causing the solution to flow from the supply flow path toward the discharge flow path in a state in which the branch valve is closed, and wherein in the merging portion, a dimension of a region adjacent to the discharge valve in the thickness direction is smaller than a dimension of a region adjacent to the

Abstract: A fluid device includes a substrate and a gas-liquid separating filter, the substrate has a flow path through which a solution flows, a reservoir, in which the solution is accommodated, connected to the flow path, an injection hole configured to connect the reservoir to the outside, and an air introduction hole branched off from the injection hole and connected to the outside, and the gas-liquid separating filter is disposed in a path of the air introduction hole, allows passage of a gas flowing through the air introduction hole, and prevents passage of a liquid flowing through the air introduction hole.

Abstract: The present invention aims at providing a fluidic device that can hold a large amount of solutions in a reservoir without depending on an attitude. The reservoir includes a meandering flow path including: a plurality of first flow paths that extend linearly along a first direction and that are arranged to be spaced in a second direction crossing the first direction; and a second flow path that extends linearly along the second direction such that a connection between first end sides of the adjacent first flow paths and a connection between second end sides of the adjacent first flow paths are alternately switched along the second direction for each first flow path, wherein the meandering flow path meanders along the second direction.

Abstract: A fluidic device that can stably supply a solution from a reservoir without causing bubbles to precede a solution is provided. The fluidic device includes a flow path into which a solution is introduced and a reservoir in which the solution is accommodated and which supplies the solution to the flow path. A length of the reservoir in a direction in which the solution flows toward the flow path is greater than a width perpendicular to the length. A width and a depth of the reservoir are formed in a size based on a capillary length which is calculated on the basis of a surface tension and a density of the solution and acceleration which includes gravity and which is applied to the solution.

Abstract: A fluidic device that can feed a fluid along a flow path without causing a leakage of gas is provided. The fluidic device includes: a first substrate and a second substrate which are bonded to each other at a bonding surface and at least one of which includes a flow path that is open on the bonding surface; and three or more valve portions that are disposed at a position facing the flow path and that are configured to adjust a flow of a fluid in the flow path by deformation. The first substrate includes a through-hole penetrating the first substrate at positions facing the valve portions. The valve portions are disposed on the same circumference centered on an axis extending in a normal direction of the bonding surface.

Abstract: A fluid device includes a base material including a flow path through which a solution flows and a first facing surface, a treatment substrate including a second facing surface which faces the first facing surface and in which a treatment unit which comes in contact with the solution and treats the solution is provided, and a sealing portion sandwiched between the first facing surface and the second facing surface, in which a treatment space surrounding the treatment unit with the sealing portion when viewed from a plate thickness direction and connected to the flow path is provided between the treatment substrate and the base material.

Abstract: A clinical trial management server 300 randomly assigns a subject to either a therapeutic group or a control group on the basis of subject assignment factor information input from a doctor terminal 200, and transmits assignment information to a subject terminal 100. In addition, in the subject terminal 100 with which the subject uses a therapeutic application, the therapeutic application is set to either a first mode that provides an actual therapeutic function or a second mode that provides a pseudo-therapeutic function on the basis of the assignment information transmitted from the clinical trial management server 300.

Abstract: Provided is an insomnia treatment assistance device including: a bedtime setting unit that sets a bedtime of a user on the basis of sleep efficiency of the user and notifies it to the user; an execution time setting unit that sets a time earlier than the bedtime by a first predetermined time as a sleepiness test execution time; and a reminder message presentation unit that presents a reminder message for prompting execution of a sleepiness test to the user at the sleepiness test execution time. The sleepiness test can be performed at an appropriate time depending on the sleep efficiency that suggests a degree of amelioration of insomnia even in a case where the sleepiness test is performed once a day. It is possible to appropriately measure user's sleepiness depending on the degree of amelioration of insomnia while minimizing a user's burden for the sleepiness test.

Abstract: A fluidic device includes: a circulation flow path; and a capture part arranged on the circulation flow path and configured to capture a sample substance in a solution and/or a detection part arranged on the circulation flow path and configured to detect a sample substance in a solution.

Abstract: Each of a plurality of node devices 200 connected by a distributed network includes a program storage unit 201 that stores a processing program for generating case report data by processing clinical trial data, a program execution unit 22 that generates case report data from clinical trial data, and a storage controller 24 that performs a consensus building process for sharing case report data among all the plurality of node devices 200 and causes a data storage unit 202 to store the case report data only when consensus is made. By preparing the case report data by execution of the processing program, falsification can be prevented in a process of preparing a case report even when a check, etc. by a third party is not included. Further, by distributing and storing the case report data in the respective node devices 200 only when validity is proved by the consensus building process, it is possible to prevent the case report from being falsified.

Abstract: Provided is an insomnia treatment assistance device including: a bedtime setting unit (14) that sets a bedtime of a user on the basis of sleep efficiency of the user and notifies it to the user; an execution time setting unit (15) that sets a time earlier than the bedtime by a first predetermined time as a sleepiness test execution time; and a reminder message presentation unit (16) that presents a reminder message for prompting execution of a sleepiness test to the user at the sleepiness test execution time. The sleepiness test can be performed at an appropriate time depending on the sleep efficiency that suggests a degree of amelioration of insomnia even in a case where the sleepiness test is performed once a day. It is possible to appropriately measure user's sleepiness depending on the degree of amelioration of insomnia while minimizing a user's burden for the sleepiness test.

Abstract: The present invention provides a fluidic device, an exosome analysis method, a biomolecule analysis method, and a biomolecule detection method, which can analyze even the content of an exosome in a series of flows by introducing a sample into the device. A fluidic device of the present invention is a fluidic device which detects a biomolecule contained in an exosome in a sample, and includes: an exosome purification unit which has a layer modified with a compound having a hydrophobic chain and a hydrophilic chain; a biomolecule purification unit; a biomolecule detection unit; a first flow path which connects the exosome purification unit to the biomolecule purification unit; and a second flow path which connects the biomolecule purification unit to the biomolecule detection unit.

Abstract: A method of manufacturing a fluidic device includes molding either one of the base member and the valve part with a first mold; and molding the other one of the base member and the valve part with a second mold with respect to the molded base member or the molded valve part.