Abstract: Described is a transdermal device comprising a backing layer; a single layer adhesive matrix comprising buprenorphine or a salt thereof, a pressure sensitive adhesive including a silicone-type adhesive blended with an acrylate-type adhesive, a solubilizer, a permeation enhancer, and a crystallization inhibitor; and a release layer. Also described is a method of relieving pain and a method of preparing a transdermal delivery system.

Abstract: The present disclosure discloses a portable business operations system having a multi-function device, a network interface and a user interface. Broadly, the multi-function device parses the content of one or more filled in application forms and verifies the completeness or accuracy of the forms. The network interface provides connectivity and communication between the portable system and one or more remotely located systems. Moreover, the user interface sends or receives electronic documents to and from one or more remotely located systems.

Abstract: The present invention relates to taste-masked pharmaceutical formulations of valacyclovir. The present invention also relates to process of preparation of valacyclovir suspensions, solutions and dry powder for reconstitution.

Abstract: A total ankle replacement system is presented. The total ankle joint replacement procedure can be used to treat persons with disability, deformity, or that are suffering from osteoarthritis and other arthritic conditions. The total ankle joint assembly generally comprises a tibial component, a talar component, and a bearing component, where the bearing component is positioned between and articulates with the tibial component and talar component to mimic the natural ankle joint movement.

Abstract: The present invention provides a catalyst composite for the synthesis of 2- and 4-picolines and a process for the preparation thereof and use thereof for the synthesis of 2- and 4-Picolines.