Patents by Inventor Tasha Nicholle SIMS

Tasha Nicholle SIMS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-angiogenic therapy of metastatic colorectal cancer
    Patent number: 11439683
    Abstract: The present invention provides methods for treating metastatic cancer comprising identifying subjects who will respond favorably to anti-VEGF therapy. According to certain aspects of the invention, subjects are identified based on their expression level of one or more predictive biomarkers. Favorable response to anti-VEGF therapy is indicated by high expression levels of certain biomarkers or by low expression levels of certain biomarkers. An exemplary predictive biomarker is VEGF-A. Also disclosed herein are prognostic biomarkers useful for identifying cancer-bearing subjects who are expected to have better relative survival outcomes.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: September 13, 2022
    Assignee: REGENERON PHARMACEUTICALS, INC.
    Inventors: Tasha Nicholle Sims, Bo Gao, Israel Lowy
  • PREDICTIVE AND PROGNOSTIC BIOMARKERS RELATED TO ANTI-ANGIOGENIC THERAPY OF METASTATIC COLORECTAL CANCER
    Publication number: 20200129589
    Abstract: The present invention provides methods for treating metastatic cancer comprising identifying subjects who will respond favorably to anti-VEGF therapy. According to certain aspects of the invention, subjects are identified based on their expression level of one or more predictive biomarkers. Favorable response to anti-VEGF therapy is indicated by high expression levels of certain biomarkers or by low expression levels of certain biomarkers. An exemplary predictive biomarker is VEGF-A. Also disclosed herein are prognostic biomarkers useful for identifying cancer-bearing subjects who are expected to have better relative survival outcomes.
    Type: Application
    Filed: November 21, 2019
    Publication date: April 30, 2020
    Applicant: REGENERON PHARMACEUTICALS, INC.
    Inventors: Tasha Nicholle SIMS, Bo GAO, Israel LOWY
  • Predictive and prognostic biomarkers related to anti-angiogenic therapy of metastatic colorectal cancer
    Patent number: 10525104
    Abstract: The present invention provides methods for treating metastatic cancer comprising identifying subjects who will respond favorably to anti-VEGF therapy. According to certain aspects of the invention, subjects are identified based on their expression level of one or more predictive biomarkers. Favorable response to anti-VEGF therapy is indicated by high expression levels of certain biomarkers or by low expression levels of certain biomarkers. An exemplary predictive biomarker is VEGF-A. Also disclosed herein are prognostic biomarkers useful for identifying cancer-bearing subjects who are expected to have better relative survival outcomes.
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: January 7, 2020
    Assignee: REGENERON PHARMACEUTICALS, INC.
    Inventors: Tasha Nicholle Sims, Bo Gao, Israel Lowy
  • PREDICTIVE AND PROGNOSTIC BIOMARKERS RELATED TO ANTI-ANGIOGENIC THERAPY OF METASTATIC COLORECTAL CANCER
    Publication number: 20170281725
    Abstract: The present invention provides methods for treating metastatic cancer comprising identifying subjects who will respond favorably to anti-VEGF therapy. According to certain aspects of the invention, subjects are identified based on their expression level of one or more predictive biomarkers. Favorable response to anti-VEGF therapy is indicated by high expression levels of certain biomarkers or by low expression levels of certain biomarkers. An exemplary predictive biomarker is VEGF-A. Also disclosed herein are prognostic biomarkers useful for identifying cancer-bearing subjects who are expected to have better relative survival outcomes.
    Type: Application
    Filed: September 10, 2015
    Publication date: October 5, 2017
    Applicant: REGENERON PHARMACEUTICALS, INC.
    Inventors: Tasha Nicholle SIMS, Bo GAO, Israel LOWY