Abstract: A method for on-demand registration of whole slide images (WSIs), comprising receiving at least two digital images, a first digital image of a reference slide and a second digital image on a candidate slide, each at a first magnification level, identifying a first region of interest (ROI) on the first digital image at a target magnification level, registering a portion of the second digital image to a portion of the first digital slide image at the first magnification level to derive a transformation matrix, applying the transformation matrix to the first ROI to identify a second ROI on the second digital image at the first magnification level, mapping the second ROI to a corresponding second ROI on the second digital image at the target magnification level, and registering the corresponding second ROI to the first ROI at the target magnification level.

Abstract: An apparatus and method for inline scanned image enrichment is provided. The apparatus includes a computing device configured to receive a plurality of subject data, generate a candidate set to model the scan focal points from, digitally capture the slide using the identified focal points through machine-learning processes, processing the captured image to optimize its viewability, and storing the captured image in an accessible repository.