Abstract: A method for making and identifying processed botanical materials as being of a pharmaceutical grade for use in clinical settings and patient treatment. The method utilizes fingerprints of the processed botanical material with respect to bioactivity and/or composition to establish whether the material meets previously established pharmaceutical grade requirements. The method is applicable to processed botanical materials, such as plant extracts, powders and the like which are used in medicinal applications.

Abstract: The present invention relates generally to St. John's Wort materials and methods for making such materials in medicinally useful and pharmaceutically acceptable forms. More particularly, the present invention relates to the use of compositional and activity fingerprints in the processing of St. John's Wort materials to produce drugs which qualify as pharmaceutical grade compositions which are suitable for use in clinical or veterinary settings to treat and/or ameliorate diseases, disorders or conditions.

Abstract: The present invention relates generally to saw palmetto materials and methods for making such materials in medicinally useful and pharmaceutically acceptable forms. More particularly, the present invention relates to the use of compositional and activity fingerprints in the processing of saw palmetto materials to produce drugs which qualify as pharmaceutical grade compositions which are suitable for use in clinical or veterinary settings to treat and/or ameliorate diseases, disorders or conditions.

Abstract: A method for making and identifying mistletoe extracts as being of a pharmaceutical grade which is useful in treating AIDS, cancers and other diseases where the immune system is suppressed. The method is based on the discovery of five marker proteins which selectively bind with different sugars. Pharmaceutical grade extracts in accordance with the invention require certain concentration levels of each protein. An additional further requirement is that each protein fraction must meet specific bioactivity levels with respect to preventing malignant cell proliferation. Fingerprint markers with respect to viscotoxins and alkaloids present in the extract are also provided. Methods of treatment using the pharmaceutical grade mistletoe are disclosed.

Abstract: A method for making and identifying mistletoe extracts as being of a pharmaceutical grade which is useful in treating AIDS, cancers and other diseases where the immune system is suppressed. The method is based on the discovery of five marker proteins which selectively bind with different sugars. Pharmaceutical grade extracts in accordance with the invention require certain concentration levels of each protein. An additional further requirement is that each protein fraction must meet specific bioactivity levels with respect to preventing malignant cell proliferation. Fingerprint markers with respect to viscotoxins and alkaloids present in the extract are also provided. Methods of treatment using the pharmaceutical grade mistletoe are disclosed.

Abstract: An aqueous mistletoe extract made from Korean mistletoe. The extract is useful in treating AIDS, cancers and other diseases where the immune system is suppressed. The extract is a pharmaceutical grade extract which has specific levels of lectins, viscotoxins and alkaloidal compounds which combine to provide the observed pharmacological activity. A lectin fingerprint of the extract is also provided.

Abstract: An aqueous mistletoe extract made from European mistletoe. The extract is useful in treating AIDS, cancers and other diseases where the immune system is suppressed. The extract is a pharmaceutical grade extract which has specific levels of lectins, viscotoxins and alkaloidal compounds which combine to provide the observed pharmacological activity. A lectin fingerprint of the extract is also provided.