Patents by Inventor Tasuku Kitada

Tasuku Kitada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for heterologous repRNA immunizations
    Patent number: 11964007
    Abstract: Compositions and methods are described for inducing an immune response against an immunogen in humans. The induced immune response is obtained by administering a heterologous prime-boost combination of an in vitro transcribed (IVT) self-replicating RNA (repRNA) and an adenovirus vector. The compositions and methods can be used to provide a protective immunity against a disease, such as a viral infection or a cancer, in humans.
    Type: Grant
    Filed: December 22, 2021
    Date of Patent: April 23, 2024
    Assignees: Janssen Vaccines & Prevention B.V., Massachusetts Institute of Technology
    Inventors: Ronald Vogels, Marijn Van Der Neut Kolfschoten, Darrell J. Irvine, Ron Weiss, Ely Blanton Porter, Mariane Bandeira Melo, Tasuku Kitada
  • LIPID NANOPARTICLE COMPRISING MODIFIED NUCLEOTIDES
    Publication number: 20230295257
    Abstract: The present disclosure relates to a lipid nanoparticle comprising (i) one or more types of lipid; and (ii) a modified mRNA comprising a sequence that encodes an interleukin (IL)-12 molecule, wherein the lipid nanoparticle is capable of triggering immunogenic cell death, and methods of treatment using the same
    Type: Application
    Filed: July 26, 2021
    Publication date: September 21, 2023
    Applicant: STRAND THERAPEUTICS INC.
    Inventors: Jacob BECRAFT, Ryan SOWELL, Jaspreet KHURANA, Tasuku KITADA
  • RNA-BASED LOGIC CIRCUITS WITH RNA BINDING PROTEINS, APTAMERS AND SMALL MOLECULES
    Publication number: 20220395585
    Abstract: Engineered synthetic RNA-based genetic circuits are provided that are regulated exclusively at the post-transcriptional level.
    Type: Application
    Filed: May 3, 2022
    Publication date: December 15, 2022
    Applicants: Massachusetts Institute of Technology, Kyoto University
    Inventors: Ron Weiss, Liliana Wroblewska, Velia Siciliano, Tasuku Kitada, Maria Hottelet Foley, Katie Bodner, Hirohide Saito, Kei Endo, Darrell J. Irvine, Tyler Wagner, Jacob Becraft
  • RNA-based logic circuits with RNA binding proteins, aptamers and small molecules
    Patent number: 11351271
    Abstract: Engineered synthetic RNA-based genetic circuits are provided that are regulated exclusively at the post-transcriptional level.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: June 7, 2022
    Assignees: Massachusetts Institute of Technology, Kyoto University
    Inventors: Ron Weiss, Liliana Wroblewska, Velia Siciliano, Tasuku Kitada, Maria Hottelet Foley, Katie Bodner, Hirohide Saito, Kei Endo, Darrell J. Irvine, Tyler Wagner, Jacob Becraft
  • Methods and Compositions for Heterologous repRNA Immunizations
    Publication number: 20220111033
    Abstract: Compositions and methods are described for inducing an immune response against an immunogen in humans. The induced immune response is obtained by administering a heterologous prime-boost combination of an in vitro transcribed (IVT) self-replicating RNA (repRNA) and an adenovirus vector. The compositions and methods can be used to provide a protective immunity against a disease, such as a viral infection or a cancer, in humans.
    Type: Application
    Filed: December 22, 2021
    Publication date: April 14, 2022
    Inventors: Ronald Vogels, Marijn Van Der Neut Kolfschoten, Darrell Irvine, Ron Weiss, Ely Porter, Mariane Bandeira Melo, Tasuku Kitada
  • Methods and compositions for heterologous repRNA immunizations
    Patent number: 11235051
    Abstract: Compositions and methods are described for inducing an immune response against an immunogen in humans. The induced immune response is obtained by administering a heterologous prime-boost combination of an in vitro transcribed (IVT) self-replicating RNA (repRNA) and an adenovirus vector. The compositions and methods can be used to provide a protective immunity against a disease, such as a viral infection or a cancer, in humans.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: February 1, 2022
    Assignees: Janssen Vaccines & Prevention B.V., Massachusetts Institute of Technology
    Inventors: Ronald Vogels, Marijn Van Der Neut Kolfschoten, Darrell J. Irvine, Ron Weiss, Ely Blanton Porter, Mariane Bandeira Melo, Tasuku Kitada
  • Lipid nanoparticles and use thereof to deliver RNA polynucleotides
    Patent number: 11026894
    Abstract: Disclosed herein are lipid nanoparticles comprising 1,2-dioleoyl-3-trimethylammonium propane (DOTAP), 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), cholesterol, and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000](DSPE-PEG2000), compositions including such lipid nanoparticles, and methods of treatment using such lipid nanoparticles and compositions.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: June 8, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Darrell J. Irvine, Ron Weiss, Tasuku Kitada, Mariane Melo, Yuan Zhang
  • METHODS AND COMPOSITIONS FOR HETEROLOGOUS REPRNA IMMUNIZATIONS
    Publication number: 20200230225
    Abstract: Compositions and methods are described for inducing an immune response against an immunogen in humans. The induced immune response is obtained by administering a heterologous prime-boost combination of an in vitro transcribed (IVT) self-replicating RNA (repRNA) and an adenovirus vector. The compositions and methods can be used to provide a protective immunity against a disease, such as a viral infection or a cancer, in humans.
    Type: Application
    Filed: July 27, 2018
    Publication date: July 23, 2020
    Inventors: Ronald VOGELS, Marijn VAN DER NEUT KOLFSCHOTEN, Darrell J. IRVINE, Ron WEISS, Ely Blanton PORTER, Mariane Bandeira MELO, Tasuku KITADA
  • LIPID NANOPARTICLES
    Publication number: 20200222332
    Abstract: Disclosed herein are lipid nanoparticles having a specific composition, compositions including such lipid nanoparticles, and methods of treatment using such lipid nanoparticles and compositions.
    Type: Application
    Filed: January 10, 2020
    Publication date: July 16, 2020
    Applicant: Massachusetts Institute of Technology
    Inventors: Darrell J. Irvine, Ron Weiss, Tasuku Kitada, Mariane Melo, Yuan Zhang
  • RNA-BASED LOGIC CIRCUITS WITH RNA BINDING PROTEINS, APTAMERS AND SMALL MOLECULES
    Publication number: 20190151474
    Abstract: Engineered synthetic RNA-based genetic circuits are provided that are regulated exclusively at the post-transcriptional level.
    Type: Application
    Filed: September 8, 2015
    Publication date: May 23, 2019
    Applicants: Massachusetts Institute of Technology, Kyoto University
    Inventors: Ron Weiss, Liliana Wroblewska, Velia Siciliano, Tasuku Kitada, Maria Hottelet Foley, Katie Bodner, Hirohide Saito, Kei Endo, Darrell J. Irvine, Tyler Wagner, Jacob Becraft
  • RNA-BASED LOGIC CIRCUITS WITH RNA BINDING PROTEINS, APTAMERS AND SMALL MOLECULES
    Publication number: 20180296702
    Abstract: Engineered synthetic RNA-based genetic circuits are provided that are regulated exclusively at the post-transcriptional level.
    Type: Application
    Filed: September 8, 2015
    Publication date: October 18, 2018
    Applicants: Massachusetts Institute of Technology, Kyoto University
    Inventors: Ron Weiss, Liliana Wroblewska, Velia Siciliano, Tasuku Kitada, Maria Hottelet Foley, Katie Bodner, Hirohide Saito, Kei Endo, Darrell J. Irvine, Tyler Wagner, Jacob Becraft