Abstract: A bag assembly that includes a bag portion having first and second walls defining an interior and an opening. The interior is formed by the first and second walls of the bag portion being attached to each other along at least a portion of a perimeter of the bag assembly up to one end of the bag portion. Portions of the first and second walls of the bag portion that are not attached to each other form the opening. The bag assembly also includes an aseptic system for sterile connection and disconnection of the bag assembly from a sterile process, the aseptic system being continuously formed at an interface between the aseptic system and the one end of the bag portion. The aseptic system includes an internal passage to allow fluid communication with the interior of the bag portion and the sterile process.

Abstract: An aseptic coupling assembly, includes a first connector and a second connector. The first connector includes a first housing, a first valve member, and a first spring that biases the first valve member towards the second end of the first housing to a first closed position. The second connector includes a second housing, a second valve member, and a second spring that biases the second valve member towards the second end of the second housing to a second closed position. The first valve member is slidable away from the first closed position within the first housing to compress the first spring and the second valve member is slidable away from the second closed position within the second housing to compress the second spring. The coupling assembly further includes a seal that prevents fluid from contacting the first spring and the second spring.

Abstract: A bag assembly that includes a bag portion having first and second walls defining an interior and an opening. The interior is formed by the first and second walls of the bag portion being attached to each other along at least a portion of a perimeter of the bag assembly up to one end of the bag portion. Portions of the first and second walls of the bag portion that are not attached to each other form the opening. The bag assembly also includes an aseptic system for sterile connection and disconnection of the bag assembly from a sterile process, the aseptic system being continuously formed at an interface between the aseptic system and the one end of the bag portion. The aseptic system includes an internal passage to allow fluid communication with the interior of the bag portion and the sterile process.

Abstract: A bioprocess bag for containing bioprocess fluids includes a frame having a first opening and a second opening, a first layer of film bonded to the frame to cover the first opening, and a second layer of film bonded to the frame to cover the second opening. The frame, the first layer of film, and the second layer of film form an enclosed space for containing the bioprocess fluids. The frame is disposed between the first layer of film and the second layer of film.