Abstract: The present disclosure relates in some aspects to methods and compositions for in situ analysis involving catalytic de-crosslinking of biological samples.

Abstract: The present disclosure relates in some aspects to methods and compositions for in situ analysis involving catalytic de-crosslinking of biological samples.

Abstract: Many mobile devices are used for documenting different scenarios that are encountered by the users as they go about their daily lives. In many situations, a mobile device may be used to document the scenario. This data may be of significant forensic interest to an investigator. In many situations, the owner of the phone may be willing to provide the investigator access to this data (through a documented consent agreement). Such consent is usually contingent upon the fact that not all the data available on the phone may be extracted for analysis, either due to privacy concerns or due to personal reasons. Courts have also opined in several cases that investigators must limit data extracted, so as to focus on only “relevant information” for the investigation at hand. Thus, only selective (or filtered) data should be extracted as per the consent available from the witness/victim (user). Described herein is the design and implementation of such a targeted data extraction system (TDES) for mobile devices.

Abstract: Pulverizers are very critical equipment in overall functioning of a plant. They need to be controlled and monitored properly for the optimized operation of the pulverizers. A system and method for performance and health monitoring to optimize operation of a pulverizer is provided. The system comprises a digital twin that can mimic the performance of the pulverizer in real-time and assist the operators in decision making related to operation, maintenance and scheduling. The digital twin is configured to receives real-time sensor data from a plurality of data sources and provides real-time soft sensing of key health and performance parameters of the pulverizer. One more key aspect of the solution is the advisory system that alerts and recommends corrective actions in terms of parameters controlled through other equipment or changes in operation or design or changes in cleaning schedule.

Abstract: The present invention relates to a novel, economically viable, storage stable, lyophilized composition of pegaspargase. The composition comprises pegaspargase, a cryoprotectant, a bulking agent, a buffer and may optionally contain other pharmaceutically acceptable excipients including but not limited to a salt. The composition of the present invention is stable for extended periods over significant range of temperatures, without the presence of any significant amount of impurities. The present invention also relates to an economically viable and scalable lyophilization process for the production of the storage stable composition of pegaspargase.

Abstract: Many mobile devices are used for documenting different scenarios that are encountered by the users as they go about their daily lives. In many situations, a mobile device may be used to document the scenario. This data may be of significant forensic interest to an investigator. In many situations, the owner of the phone may be willing to provide the investigator access to this data (through a documented consent agreement). Such consent is usually contingent upon the fact that not all the data available on the phone may be extracted for analysis, either due to privacy concerns or due to personal reasons. Courts have also opined in several cases that investigators must limit data extracted, so as to focus on only “relevant information” for the investigation at hand. Thus, only selective (or filtered) data should be extracted as per the consent available from the witness/victim (user). Described herein is the design and implementation of such a targeted data extraction system (TDES) for mobile devices.

Abstract: A method for localizing for GPS denied environments is provided with a plurality of broadcasting transmitters and a software-defined radio (SDR). A pre-processing stage and a query phase is executed for localizing an unknown location. The results from the preprocessing stage are made available to the query stage. A simulated power spectrum is computed for a region of interest during the pre-processing phase via the plurality of broadcasting transmitters. A transmitter location, a radius of influence, and a power contour plot of each of the plurality of broadcasting transmitters are used for computing the simulated power spectrum. Next, a peak-finding process, a filtering process, and a localization process is executed during the query phase in order to identify the unknown location.

Abstract: A method for localizing for GPS denied environments is provided with a plurality of broadcasting transmitters and a software-defined radio (SDR). A pre-processing stage and a query phase is executed for localizing an unknown location. The results from the preprocessing stage are made available to the query stage. A simulated power spectrum is computed for a region of interest during the pre-processing phase via the plurality of broadcasting transmitters. A transmitter location, a radius of influence, and a power contour plot of each of the plurality of broadcasting transmitters are used for computing the simulated power spectrum. Next, a peak-finding process, a filtering process, and a localization process is executed during the query phase in order to identify the unknown location.