Patents by Inventor Tatiana Byzova

Tatiana Byzova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for modulating toll-like receptor 2 activation
    Patent number: 10987408
    Abstract: A method of promoting hair growth of a subject includes administering to follicle cells of the subject a therapeutically effective amount of a TLR2 agonist that promotes TLR2 activation and hair growth of the subject.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: April 27, 2021
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventor: Tatiana Byzova
  • COMPOSITIONS AND METHODS FOR MODULATING TOLL-LIKE RECEPTOR 2 ACTIVATION
    Publication number: 20180280482
    Abstract: A method of promoting hair growth of a subject includes administering to follicle cells of the subject a therapeutically effective amount of a TLR2 agonist that promotes TLR2 activation and hair growth of the subject.
    Type: Application
    Filed: May 2, 2018
    Publication date: October 4, 2018
    Inventor: Tatiana Byzova
  • Compositions and methods for modulating toll-like receptor 2 activation
    Patent number: 9981018
    Abstract: A method of promoting hair growth of a subject includes administering to follicle cells of the subject a therapeutically effective amount of a TLR2 agonist that promotes TLR2 activation and hair growth of the subject.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: May 29, 2018
    Assignee: The Cleveland Clinic Foundation
    Inventor: Tatiana Byzova
  • COMPOUNDS AND METHODS OF MODULATING ANGIOGENESIS
    Publication number: 20170198023
    Abstract: A pharmaceutical composition includes a synthetic peptide consisting of about 10 to about 50 amino acids and having an amino acid sequence substantially homologous to consecutive amino acids of a portion of the cytoplasmic doman of at least one of ?v?3 integrin or VEGFR2 that includes a tyrosine residue, the amino acid sequence of the peptide including a phosphorylated tyrosine residue or a ?-carboxyglutamic acid residue that is substituted for a corresponding tyrosine residue of the portion of the cytoplasmic domain of ?v?3 integrin or VEGFR2.
    Type: Application
    Filed: March 13, 2017
    Publication date: July 13, 2017
    Inventors: Tatiana Byzova, Ganapati H. Mahabaleshwar, Weiyi Feng
  • Compounds and methods of modulating angiogenesis
    Patent number: 9592269
    Abstract: A pharmaceutical composition includes a synthetic peptide consisting of about 10 to about 50 amino acids and having an amino acid sequence substantially homologous to consecutive amino acids of a portion of the cytoplasmic domain of at least one of ?v?3 integrin or VEGFR2 that includes a tyrosine residue, the amino acid sequence of the peptide including a phosphorylated tyrosine residue or a ?-carboxyglutamic acid residue that is substituted for a corresponding tyrosine residue of the portion of the cytoplasmic domain of ?v?3 integrin or VEGFR2.
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: March 14, 2017
    Assignee: The Cleveland Clinic Foundation
    Inventors: Tatiana Byzova, Ganapati H. Mahabaleshwar, Weiyi Feng
  • COMPOUNDS AND METHODS OF MODULATING ANGIOGENESIS
    Publication number: 20160101151
    Abstract: A pharmaceutical composition includes a synthetic peptide consisting of about 10 to about 50 amino acids and having an amino acid sequence substantially homologous to consecutive amino acids of a portion of the cytoplasmic domain of at least one of ?v?3 integrin or VEGFR2 that includes a tyrosine residue, the amino acid sequence of the peptide including a phosphorylated tyrosine residue or a ?-carboxyglutamic acid residue that is substituted for a corresponding tyrosine residue of the portion of the cytoplasmic domain of ?v?3 integrin or VEGFR2.
    Type: Application
    Filed: November 10, 2015
    Publication date: April 14, 2016
    Inventors: Tatiana Byzova, Ganapati H. Mahabaleshwar, Weiyi Feng
  • Compounds and methods of modulating angiogenesis
    Patent number: 9180164
    Abstract: A pharmaceutical composition includes a synthetic peptide consisting of about 10 to about 50 amino acids and having an amino acid sequence substantially homologous to consecutive amino acids of a portion of the cytoplasmic domain of at least one of ?v?3 integrin or VEGFR2 that includes a tyrosine residue, the amino acid sequence of the peptide including a phosphorylated tyrosine residue or a ?-carboxyglutamic acid residue that is substituted for a corresponding tyrosine residue of the portion of the cytoplasmic domain of ?v?3 integrin or VEGFR2.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: November 10, 2015
    Assignee: The Cleveland Clinic Foundation
    Inventors: Tatiana Byzova, Ganapati H. Mahabaleshwar, Weiyi Feng
  • COMPOUNDS AND METHODS OF MODULATING ANGIOGENESIS
    Publication number: 20140135264
    Abstract: A pharmaceutical composition includes a synthetic peptide consisting of about 10 to about 50 amino acids and having an amino acid sequence substantially homologous to consecutive amino acids of a portion of the cytoplasmic domain of at least one of ?v?3 integrin or VEGFR2 that includes a tyrosine residue, the amino acid sequence of the peptide including a phosphorylated tyrosine residue or a ?-carboxyglutamic acid residue that is substituted for a corresponding tyrosine residue of the portion of the cytoplasmic domain of ?v?3 integrin or VEGFR2.
    Type: Application
    Filed: December 14, 2012
    Publication date: May 15, 2014
    Applicant: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Tatiana Byzova, Ganapati Bhat, Weiyi Feng
  • Compounds and methods of modulating angiogenesis
    Patent number: 8080252
    Abstract: A method of modulating angiogenesis in a tissue comprises administering to the tissue a therapeutically effective amount of an agent that modulates complex formation of ?v?3 integrin and VEGFR2.
    Type: Grant
    Filed: January 21, 2009
    Date of Patent: December 20, 2011
    Assignee: The Cleveland Clinic Foundation
    Inventors: Tatiana Byzova, Ganapati H. Maha Baleshuar, Weiyi Feng
  • COMPOUNDS AND METHODS OF MODULATING ANGIOGENESIS
    Publication number: 20090298769
    Abstract: A method of modulating angiogenesis in a tissue comprises administering to the tissue a therapeutically effective amount of an agent that modulates complex formation of ?v?3 integrin and VEGFR2.
    Type: Application
    Filed: January 21, 2009
    Publication date: December 3, 2009
    Inventors: TATIANA BYZOVA, Ganapati H. Baleshuar, Weiyi Feng