Patents by Inventor Tatiana Kolesnik

Tatiana Kolesnik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11104735
    Abstract: The present invention relates to therapeutic and prophylactic methods based on inhibition of CIS in NK cells. In particular, the present invention relates to treating or preventing a NK-responsive condition by administering to a subject a CIS inhibitor, or administering CIS-inhibited NK cells. The invention further relates to methods for identifying a CIS inhibitor, and for determining a likelihood of cancer response to treatment with CIS inhibition.
    Type: Grant
    Filed: December 9, 2020
    Date of Patent: August 31, 2021
    Assignee: The Walter and Eliza Hall Institute of Medical Research
    Inventors: Nicholas D. Huntington, Sandra E. Nicholson, Jeff Babon, Tatiana Kolesnik
  • Publication number: 20210171636
    Abstract: The present invention relates to therapeutic and prophylactic methods based on inhibition of CIS in NK cells. In particular, the present invention relates to treating or preventing a NK-responsive condition by administering to a subject a CIS inhibitor, or administering CIS-inhibited NK cells.
    Type: Application
    Filed: December 9, 2020
    Publication date: June 10, 2021
    Inventors: Nicholas D. Huntington, Sandra E. Nicholson, Jeff Babon, Tatiana Kolesnik
  • Patent number: 10975149
    Abstract: The present invention relates to therapeutic and prophylactic methods based on inhibition of CIS in NK cells. In particular, the present invention relates to treating or preventing a NK-responsive condition by administering to a subject a CIS inhibitor, or administering CIS-inhibited NK cells. The invention further relates to methods for identifying a CIS inhibitor, and for determining a likelihood of cancer response to treatment with CIS inhibition.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: April 13, 2021
    Inventors: Nicholas D. Huntington, Sandra E. Nicholson, Jeff Babon, Tatiana Kolesnik
  • Publication number: 20180298101
    Abstract: The present invention relates to therapeutic and prophylactic methods based on inhibition of CIS in NK cells. In particular, the present invention relates to treating or preventing a NK-responsive condition by administering to a subject a CIS inhibitor, or administering CIS-inhibited NK cells. The invention further relates to methods for identifying a CIS inhibitor, and for determining a likelihood of cancer response to treatment with CIS inhibition.
    Type: Application
    Filed: December 16, 2016
    Publication date: October 18, 2018
    Inventors: Nicholas D. Huntington, Sandra E. Nicholson, Jeff Babon, Tatiana Kolesnik
  • Publication number: 20120308570
    Abstract: The present invention relates to methods of modulating the level of inducible nitric oxide synthase (iNOS) in a cell which comprises administering to the cell a compound which modulates binding of SPRY domain-containing SOCS box protein (SSB) to iNOS, and/or a compound which modulates SSB activity in the cell. Further provided are methods of treating or preventing disease in a subject by modulating the level of iNOS in a cell, as well as compounds which modulate binding of SSB to iNOS and compounds which modulate SSB activity.
    Type: Application
    Filed: May 6, 2010
    Publication date: December 6, 2012
    Inventors: Tatiana Kolesnik, Zhihe Kuang, Rowena Sue Lewis, Sandra Elaine Nicholson, Ray Norton
  • Publication number: 20080271210
    Abstract: The present invention is directed to a novel gene, Oslrk1, that is in involved in plant development, including root expansion. Methods of influencing this development are also described, as are transformed cells and transgenic plants comprising the described sequences.
    Type: Application
    Filed: October 1, 2005
    Publication date: October 30, 2008
    Applicant: Temasek Life Sciences Laboratory National University of Singapore
    Inventors: Tatiana Kolesnik, Ritu Bhalla, Rengasamy Ramamoorthy, Srinivasan Ramachandran