Patents by Inventor Tatiana Plavina

Tatiana Plavina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quantitative antibody test
    Patent number: 11686730
    Abstract: The present disclosure relates to methods and compositions, e.g., kits, for quantitatively detecting an antibody of a subject to an infectious organism. In some embodiments, the present disclosure provides for methods and compositions, e.g., kits, for quantitatively detecting a human antibody to SARS-CoV-2 polypeptide or S (spike) polypeptide. Certain applications and uses of the present methods and compositions, e.g., kits, are also provided.
    Type: Grant
    Filed: April 28, 2021
    Date of Patent: June 27, 2023
    Assignee: Quanterix Corporation
    Inventors: Andrew Ball, Lei Chang, Syrena Fernandes, Joe Johnson, Jeremy Lambert, Dawn Mattoon, Tatiana Plavina, David Wilson
  • METHOD OF ASSESSING RISK OF PML
    Publication number: 20220357339
    Abstract: The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML).
    Type: Application
    Filed: March 21, 2022
    Publication date: November 10, 2022
    Inventors: Gary Lewis BLOOMGREN, Carmen BOZIC, Sophia LEE, Amy PACE, Tatiana PLAVINA, Meena SUBRAMANYAM
  • ANTI-VLA-4 RELATED ASSAYS
    Publication number: 20220357338
    Abstract: Methods and apparatus for assaying the level of analytes in a sample, related to VLA-4, are disclosed. A method of decreasing the level of an anti-integrin antibody in a subject is described including a) contacting a biological sample from a subject with a detectable capture agent associated with a substrate, wherein the capture agent can bind an anti-integrin antibody in the sample; b) detecting binding of the capture agent with the level of the anti-integrin antibody; and c) treating the subject with plasma exchange until the level of the anti-integrin antibody in the sample reaches a predetermined level.
    Type: Application
    Filed: March 21, 2022
    Publication date: November 10, 2022
    Inventors: Tatiana Plavina, Paula S. Hochman, Michaela Lerner
  • BIOMARKERS OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY
    Publication number: 20220128578
    Abstract: Featured are biomarkers for progressive multifocal leukoencephalopathy (PML). Also provided are methods for reducing the occurrence or severity of PML during immunomodulator therapy or identification of PML in an immunocompromised subject.
    Type: Application
    Filed: February 11, 2020
    Publication date: April 28, 2022
    Inventors: Tatiana PLAVINA, Carol Margaret SINGH
  • Method of assessing risk of PML
    Patent number: 11280794
    Abstract: The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML).
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: March 22, 2022
    Assignee: Biogen MA Inc.
    Inventors: Gary Lewis Bloomgren, Carmen Bozic, Sophia Lee, Amy Pace, Tatiana Plavina, Meena Subramanyam
  • Anti-VLA-4 related assays
    Patent number: 11280793
    Abstract: Methods and apparatus for assaying the level of analytes in a sample, related to VLA-4, are disclosed. A method of decreasing the level of an anti-integrin antibody in a subject is described including a) contacting a biological sample from a subject with a detectable capture agent associated with a substrate, wherein the capture agent can bind an anti-integrin antibody in the sample; b) detecting binding of the capture agent with the level of the anti-integrin antibody; and c) treating the subject with plasma exchange until the level of the anti-integrin antibody in the sample reaches a predetermined level.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: March 22, 2022
    Assignee: BIOGEN MA INC.
    Inventors: Tatiana Plavina, Paula S. Hochman, Michaela Lerner
  • METHODS AND KITS FOR DETECTING SARS-CORONAVIRUS-2 ANTIGEN
    Publication number: 20220050106
    Abstract: The present disclosure relates to methods and compositions, e.g., kits, for assessing or detecting SARS-CoV-2 antigen(s), e.g., SARS-CoV-2 nucleocapsid protein (N-protein), in a sample or a blood sample, e.g., serum, plasma, dried blood spots (DBS) and/or a saliva sample. Certain applications and uses of the present methods and compositions, e.g., kits, are also provided.
    Type: Application
    Filed: August 11, 2021
    Publication date: February 17, 2022
    Applicant: Quanterix Corporation
    Inventors: Andrew Ball, Lei Chang, Syrena Fernandes, Kevin Hrusovsky, Joseph Johnson, Dawn Mattoon, Tatiana Plavina, Dandan Shan, David Wilson
  • METHOD OF ASSESSING RISK OF PML
    Publication number: 20220011310
    Abstract: The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML).
    Type: Application
    Filed: August 3, 2021
    Publication date: January 13, 2022
    Inventors: Gary Lewis Bloomgren, Carmen Bozic, Sophia Lee, Meena Subramanyam, Tatiana Plavina
  • QUANTITATIVE ANTIBODY TEST
    Publication number: 20210341479
    Abstract: The present disclosure relates to methods and compositions, e.g., kits, for quantitatively detecting an antibody of a subject to an infectious organism. In some embodiments, the present disclosure provides for methods and compositions, e.g., kits, for quantitatively detecting a human antibody to SARS-CoV-2 polypeptide or S (spike) polypeptide. Certain applications and uses of the present methods and compositions, e.g., kits, are also provided.
    Type: Application
    Filed: April 28, 2021
    Publication date: November 4, 2021
    Applicant: Quanterix Corporation
    Inventors: Andrew Ball, Lei Chang, Syrena Fernandes, Joe Johnson, Jeremy Lambert, Dawn Mattoon, Tatiana Plavina, David Wilson
  • Method of assessing risk of PML
    Patent number: 10955422
    Abstract: The invention relates to methods of assessing a patient's risk of developing Progressive Multifocal Leukoencephalopathy (PML).
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: March 23, 2021
    Assignee: Biogen MA, Inc.
    Inventors: Tatiana Plavina, John P. Carulli, Leonid Gorelik, Teresa Compton
  • METHOD OF ASSESSING RISK OF PML
    Publication number: 20200408776
    Abstract: The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML).
    Type: Application
    Filed: June 8, 2020
    Publication date: December 31, 2020
    Inventors: Gary Lewis BLOOMGREN, Carmen BOZIC, Sophia LEE, Amy PACE, Tatiana PLAVINA, Meena SUBRAMANYAM
  • Method of assessing risk of PML
    Patent number: 10677803
    Abstract: The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML).
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: June 9, 2020
    Assignee: Biogen MA Inc.
    Inventors: Gary Lewis Bloomgren, Carmen Bozic, Sophia Lee, Amy Pace, Tatiana Plavina, Meena Subramanyam
  • ANTI-VLA-4 RELATED ASSAYS
    Publication number: 20200088738
    Abstract: Methods and apparatus for assaying the level of analytes in a sample, related to VLA-4, are disclosed. A method of decreasing the level of an anti-integrin antibody in a subject is described including a) contacting a biological sample from a subject with a detectable capture agent associated with a substrate, wherein the capture agent can bind an anti-integrin antibody in the sample; b) detecting binding of the capture agent with the level of the anti-integrin antibody; and c) treating the subject with plasma exchange until the level of the anti-integrin antibody in the sample reaches a predetermined level.
    Type: Application
    Filed: May 24, 2019
    Publication date: March 19, 2020
    Inventors: Tatiana Plavina, Paula S. Hochman, Michaela Lerner
  • METHOD OF ASSESSING RISK OF PML
    Publication number: 20190227064
    Abstract: The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML).
    Type: Application
    Filed: December 5, 2018
    Publication date: July 25, 2019
    Inventors: Gary Lewis Bloomgren, Carmen Bozic, Sophia Lee, Meena Subramanyam, Tatiana Plavina
  • Anti-VLA-4 related assays
    Patent number: 10302654
    Abstract: Methods and apparatus for assaying the level of analytes in a sample, related to VLA-4, are disclosed. A method of decreasing the level of an anti-integrin antibody in a subject is described including a) contacting a biological sample from a subject with a detectable capture agent associated with a substrate, wherein the capture agent can bind an anti-integrin antibody in the sample; b) detecting binding of the capture agent with the level of the anti-integrin antibody; and c) treating the subject with plasma exchange until the level of the anti-integrin antibody in the sample reaches a predetermined level.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: May 28, 2019
    Assignee: BIOGEN MA INC.
    Inventors: Tatiana Plavina, Paula S. Hochman, Michaela Lerner
  • METHOD OF ASSESSING RISK OF PML
    Publication number: 20190137511
    Abstract: The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML).
    Type: Application
    Filed: August 28, 2018
    Publication date: May 9, 2019
    Inventors: Gary Lewis BLOOMGREN, Carmen BOZIC, Sophia LEE, Amy PACE, Tatiana PLAVINA, Meena SUBRAMANYAM
  • Method of assessing risk of PML
    Patent number: 10119976
    Abstract: The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML).
    Type: Grant
    Filed: May 27, 2014
    Date of Patent: November 6, 2018
    Assignee: Biogen MA Inc.
    Inventors: Gary Lewis Bloomgren, Carmen Bozic, Sophia Lee, Amy Pace, Tatiana Plavina, Meena Subramanyam
  • ANTI-VLA-4 RELATED ASSAYS
    Publication number: 20180143204
    Abstract: Methods and apparatus for assaying the level of analytes in a sample, related to VLA-4, are disclosed. A method of decreasing the level of an anti-integrin antibody in a subject is described including a) contacting a biological sample from a subject with a detectable capture agent associated with a substrate, wherein the capture agent can bind an anti-integrin antibody in the sample; b) detecting binding of the capture agent with the level of the anti-integrin antibody; and c) treating the subject with plasma exchange until the level of the anti-integrin antibody in the sample reaches a predetermined level.
    Type: Application
    Filed: June 29, 2017
    Publication date: May 24, 2018
    Inventors: Tatiana Plavina, Paula S. Hochman, Michaela Lerner
  • Anti-VLA-4 related assays
    Patent number: 9726672
    Abstract: Methods and apparatus for assaying the level of analytes in a sample, related to VLA-4, are disclosed. A method of decreasing the level of an anti-integrin antibody in a subject is described including a) contacting a biological sample from a subject with a detectable capture agent associated with a substrate, wherein the capture agent can bind an anti-integrin antibody in the sample; b) detecting binding of the capture agent with the level of the anti-integrin antibody; and c) treating the subject with plasma exchange until the level of the anti-integrin antibody in the sample reaches a predetermined level.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: August 8, 2017
    Assignee: Biogen MA Inc.
    Inventors: Tatiana Plavina, Paula S. Hochman, Michaela Lerner
  • METHOD OF ASSESSING RISK OF PML
    Publication number: 20170016919
    Abstract: The invention relates to methods of assessing a patient's risk of developing Progressive Multifocal Leukoencephalopathy (PML).
    Type: Application
    Filed: February 27, 2015
    Publication date: January 19, 2017
    Inventors: Tatiana Plavina, John P. Carulli, Leonid Gorelik, Teresa Compton