Patents by Inventor Tatjana YURKSHTOVICH

Tatjana YURKSHTOVICH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stable anti-neoplastic pharmaceutical composition comprising temozolomide and method of preparing the composition
    Patent number: 10806732
    Abstract: An anti-neoplastic stable pharmaceutical composition comprising Temozolomide, high substituted polysaccharide phosphate in salt form, and high substituted polysaccharide phosphate in acidic form, in particular in a weight ratio of from 5 to 20% Temozolomide to 30 to 80% of polysaccharide in salt form, the reminder up to 100% being polysaccharide in acidic form. The level of 5-aminomidazole-4-carboxamide is below 0.5% by weight of Temozolomide in both the composition and the formulation disclosed. Also disclosed is a hydrogel for intrathecal administration obtainable by contacting the composition with sterile water, a method of manufacture of the composition and uses of the composition and the gel.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: October 20, 2020
    Assignees: Double Bond Pharmaceutical AB, Research Institute of Physical Chemical Problems of the Belarulsna State University
    Inventors: Mikalai Yurkshtovich, Dzmitry Veyeunik, Valiantsina Alinouskaya, Natalia Atrakhimovich, Iryna Halouchyk, Sergey Beliaev, Tatjana Yurkshtovich, Pavel Bychkouski, Aliaksandr Fedulau, Tatsiana Trukhachova
  • STABLE ANTI-NEOPLASTIC PHARMACEUTICAL COMPOSITION COMPRISING TEMOZOLOMIDE AND METHOD OF PREPARING THE COMPOSITION
    Publication number: 20190142824
    Abstract: An anti-neoplastic stable pharmaceutical composition comprising Temozolomide, high substituted polysaccharide phosphate in salt form, and high substituted polysaccharide phosphate in acidic form, in particular in a weight ratio of from 5 to 20% Temozolomide to 30 to 80% of polysaccharide in salt form, the reminder up to 100% being polysaccharide in acidic form. The level of 5-aminomidazole-4-carboxamide is below 0.5% by weight of Temozolomide in both the composition and the formulation disclosed. Also disclosed is a hydrogel for intrathecal administration obtainable by contacting the composition with sterile water, a method of manufacture of the composition and uses of the composition and the gel.
    Type: Application
    Filed: April 28, 2017
    Publication date: May 16, 2019
    Inventors: Yurkshtovich MIKALAI, Veyeunik DZMITRY, Alinouskaya VALIANTSINA, Natalia ATRAKHIMOVICH, Lryna HALOUCHYK, Sergey BELIAEV, Tatjana YURKSHTOVICH, Pavel BYCHKOUSKI, Aliaksandr FEDULAU, Tatsiana TRUKHACHOVA