Patents by Inventor Tatos N. Akopian

Tatos N. Akopian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for identifying agents that interact with beta-site APP cleaving enzyme (BACE)
    Patent number: 7630838
    Abstract: This invention is directed to the three dimensional crystal structure of Beta-site APP Cleaving Enzyme (BACE), and to the use of this structure in rational drug design methods to identify agents that may interact with active sites of BACE. Such agents may represent new therapeutics in the treatment and/or prevention of Alzheimer's Disease.
    Type: Grant
    Filed: September 19, 2001
    Date of Patent: December 8, 2009
    Assignee: American Home Products Corporation
    Inventors: Rajiv Chopra, Kristine Svenson, Bethany Annis Freeman, Tatos N. Akopian, Jonathan Bard, Mark Lloyd Stahl, William S. Somers
  • Crystal structure of estrogen receptor-beta complex and uses thereof
    Publication number: 20080227960
    Abstract: This invention is directed to the crystal structure of Estrogen Receptor-? (ER-?) complexed with genistein, and to the use of this structure in rational drug design methods to identify agents that may interact with active sites of ER-?, which may be useful as novel chemotherapeutic agents.
    Type: Application
    Filed: April 13, 2007
    Publication date: September 18, 2008
    Applicant: Genetics Institute, LLC.
    Inventors: William S. Somers, Zhang-Bao Xu, Tatos N. Akopian, Chu-Lai Hsiao, Rayomand Unwalla
  • Method using crystal structure of estrogen receptor-? complex
    Patent number: 7235367
    Abstract: This invention is directed to the crystal structure of Estrogen Receptor-? (ER-?) complexed with genistein, and to the use of this structure in rational drug design methods to identify agents that may interact with active sites of ER-?, which may be useful as novel chemotherapeutic agents.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: June 26, 2007
    Assignee: Genetics Institute, LLC.
    Inventors: William S. Somers, Zhang-Bao Xu, Tatos N. Akopian, Chu-Lai Hsiao, Rayomand Unwalla
  • Crystal structure of estrogen receptor-beta complex and uses thereof
    Publication number: 20020072587
    Abstract: This invention is directed to the crystal structure of Estrogen Receptor-&bgr; (ER-&bgr;) complexed with genistein, and to the use of this structure in rational drug design methods to identify agents that may interact with active sites of ER-&bgr;, which may be useful as novel chemotherapeutic agents.
    Type: Application
    Filed: July 11, 2001
    Publication date: June 13, 2002
    Inventors: William S. Somers, Zhang-Bao Xu, Tatos N. Akopian, Chu-Lai Hsiao, Rayomand Unwalla
  • Crystal structure of bace and uses thereof
    Publication number: 20020055459
    Abstract: This invention is directed to the three dimensional crystal structure of Beta-site APP Cleaving Enzyme (BACE), and to the use of this structure in rational drug design methods to identify agents that may interact with active sites of BACE. Such agents may represent new therapeutics in the treatment and/or prevention of Alzheimer's Disease.
    Type: Application
    Filed: September 19, 2001
    Publication date: May 9, 2002
    Inventors: Rajiv Chopra, Kristine Svenson, Bethany Annis, Tatos N. Akopian, Jonathan Bard, Mark Lloyd Stahl, William S. Somers