Patents by Inventor Tatsuhiro Ishida

Tatsuhiro Ishida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Agent for enhancing anti-tumor effect comprising oxaliplatin liposome preparation, and anti-tumor agent comprising the liposome preparation
    Patent number: 8940327
    Abstract: An object of the present invention is to further enhance the antitumor effect when oxaliplatin is administered in combination with a combination drug containing tegafur, gimeracil and oteracil potassium. According to the present invention, by using oxaliplatin encapsulated in a liposome preparation, combination therapy of oxaliplatin plus a combination drug containing tegafur, gimeracil and oteracil potassium, is revealed to show remarkably enhanced antitumor effect without increasing side effects.
    Type: Grant
    Filed: January 29, 2009
    Date of Patent: January 27, 2015
    Assignees: The University of Tokushima, Taiho Pharmaceutical Co. Ltd.
    Inventors: Tatsuhiro Ishida, Hiroshi Kiwada
  • Liposome containing shRNA molecule targeting a thymidylate synthase and use thereof
    Patent number: 8592572
    Abstract: This method provides a method for delivering shRNA targeting TS in vivo. In addition, the following is provided: an antitumor agent, which comprises short hairpin RNA (shRNA) capable of inhibiting expression of thymidylate synthase by RNAi action and a PEG-modified cationic liposome, wherein the shRNA is bound to the surface of the PEG-modified cationic liposome and has an overhang comprising at least two nucleotides at the 3? end.
    Type: Grant
    Filed: August 22, 2012
    Date of Patent: November 26, 2013
    Assignee: Delta-Fly Pharma, Inc.
    Inventors: Tatsuhiro Ishida, Cheng Long Huang, Hiromi Wada
  • LIPOSOME CONTAINING shRNA MOLECULE TARGETING A THYMIDYLATE SYNTHASE AND USE THEREOF
    Publication number: 20130058996
    Abstract: This method provides a method for delivering shRNA targeting TS in vivo. In addition, the following is provided: an antitumor agent, which comprises short hairpin RNA (shRNA) capable of inhibiting expression of thymidylate synthase by RNAi action and a PEG-modified cationic liposome, wherein the shRNA is bound to the surface of the PEG-modified cationic liposome and has an overhang comprising at least two nucleotides at the 3? end.
    Type: Application
    Filed: August 22, 2012
    Publication date: March 7, 2013
    Applicant: DELTA-FLY PHARMA, INC.
    Inventors: Tatsuhiro ISHIDA, Cheng Long HUANG, Hiromi WADA
  • LIPOSOME CONTAINING shRNA MOLECULE TARGETING A THYMIDYLATE SYNTHASE AND USE THEREOF
    Publication number: 20120301537
    Abstract: This method provides a method for delivering shRNA targeting TS in vivo. In addition, the following is provided: an antitumor agent, which comprises short hairpin RNA (shRNA) capable of inhibiting expression of thymidylate synthase by RNAi action and a PEG-modified cationic liposome, wherein the shRNA is bound to the surface of the PEG-modified cationic liposome and has an overhang comprising at least two nucleotides at the 3? end.
    Type: Application
    Filed: October 14, 2011
    Publication date: November 29, 2012
    Applicant: DELTA-FLY PHARMA, INC.
    Inventors: Tatsuhiro ISHIDA, Cheng Long HUANG, Hiromi WADA
  • AGENT FOR ENHANCING ANTI-TUMOR EFFECT COMPRISING OXALIPLATIN LIPOSOME PREPARATION, AND ANTI-TUMOR AGENT COMPRISING THE LIPOSOME PREPARATION
    Publication number: 20100330166
    Abstract: An object of the present invention is to further enhance the antitumor effect when oxaliplatin is administered in combination with a combination drug containing tegafur, gimeracil and oteracil potassium. According to the present invention, by using oxaliplatin encapsulated in a liposome preparation, combination therapy of oxaliplatin plus a combination drug containing tegafur, gimeracil and oteracil potassium, is revealed to show remarkably enhanced antitumor effect without increasing side effects.
    Type: Application
    Filed: January 29, 2009
    Publication date: December 30, 2010
    Applicants: The University of Tokushima, Taiho Pharmaceutical Co., Ltd.
    Inventors: Tatsuhiro Ishida, Hiroshi Kiwada
  • POLYOXYALKYLENE CHAIN-CONTAINING LIPID DERIVATIVE AND LIPID FILM STRUCTURE CONTAINING SUCH DERIVATIVE
    Publication number: 20090202619
    Abstract: A polyoxyalkylene chain-containing lipid derivative, which is represented by the following formula (1): wherein L, Y, W, X1, X2, X3, OA, Z, m1, m2, m3, n1, n2 and n3 are as defined in the specification.
    Type: Application
    Filed: February 17, 2006
    Publication date: August 13, 2009
    Applicants: THE UNIVERSITY OF TOKUSHIMA, NOF CORPORATION
    Inventors: Hiroshi Kiwada, Tatsuhiro Ishida, Chika Ito, Kazuhiro Kubo, Kenji Sakanoue, Hiroshi Kikuchi