Abstract: The purpose of the present invention is to provide a novel stereoselective method for preparing a cyclic dinucleotide derivative and a production intermediate therefor, which can be used for an antibody-immunostimulant conjugate. Also provided is a method for producing a cyclic dinucleotide-linker and an antibody-immunostimulant conjugate while using the above production method. Further provided is a method for preparing a cyclic dinucleotide derivative, the method including the step of subjecting a compound (I) and a compound (IV) to stereoselective condensation using an optically active phosphitylating agent (Rc-II) or (Sc-II).

Abstract: Implementation including a brain activity data acquisition unit configured to acquire data on brain activity of a human body; a generator configured to generate a stimulation signal based on predetermined stimulation parameters or stimulation parameters determined from the data acquired by the brain activity data acquisition unit, the stimulation signal being to be applied, for activity of a specific brain region to be activated in order to move a joint of the human body, to a nerve corresponding to the specific brain region; and an output unit configured to output the stimulation signal generated by the generator.

Abstract: Implementation including a brain activity data acquisition unit (103) configured to acquire data on brain activity of a human body; a generator (101) configured to generate a stimulation signal based on predetermined stimulation parameters or stimulation parameters determined from the data acquired by the brain activity data acquisition unit, the stimulation signal being to be applied, for activity of a specific brain region to be activated in order to move a joint of the human body, to a nerve corresponding to the specific brain region; and an output unit (102) configured to output the stimulation signal generated by the generator.

Abstract: A dielectric lens which is produced by injection molding of an expandable material consisting of a synthetic resin, a foaming agent and a dielectric constant conditioner. The expandable material is injected into a cavity of a foaming mold up to at least about 80 percent by weight and at least about 100 percent by volume of the capacity of the cavity and is foamed at an expansion ratio of not more than about 1.3. During the foam molding, the surface of the foam-molded body is solidified to be a radome layer. Then, the foam-molded body is transferred from the foaming mold to a shaping mold, in which the foam-molded is cooled down naturally. Further, a fitting tab is provided integrally with the foam-molded body at the edge of the radome layer.

Abstract: The present invention is for providing a production method of a dielectric lens with the excellent productivity, capable of achieving the shape accuracy or density homogeneity of the demanded level, and capable of injection molding of a matching layer without forming a gap with respect to a lens main body. A lens main body is formed by the injection compression molding method, using a composite dielectric material containing a thermoplastic resin as the dielectric material for the lens main body. After forming a matching layer (first surface side matching layer) on either surface of the front or rear surfaces (first surface) side of the lens main body, and injecting a matching layer material, a matching layer (second surface side matching layer) is formed on the other surface of the lens main body (that is, the matching layer is formed by the two operation injection molding method of injecting to one surface side of the lens main body, and then injection to the other surface side).