Patents by Inventor Tatsuki Shiota

Tatsuki Shiota has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic amine CCR3 antagonist
    Patent number: 7576117
    Abstract: A medicine containing, as an active ingredient, a cyclic amine derivative represented by the following formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1 to C6 alkyl addition salt thereof. The medicine has an action for treating or preventing diseases in which CCR3 participates, such as asthma and allergic rhinitis.
    Type: Grant
    Filed: August 4, 2000
    Date of Patent: August 18, 2009
    Assignee: Teijin Limited
    Inventors: Tatsuki Shiota, Masaki Sudoh, Tomonori Yokoyama, Yumiko Muroga, Takashi Kamimura, Akinobu Nakanishi
  • Remedies or prophylactics for diseases in association with chemokines
    Patent number: 7390830
    Abstract: This invention provides remedies or prophylactics for diseases in association with chemokines such as MIP-1 ? and/or MCP-1. Namely, remedies or prophylactics for diseases in association with the chemokines such as rheumatoid arthritis or nephritis contain, as the active ingredient, cyclic amine derivatives represented by the following formula (I), pharmaceutically acceptable acid addition salts thereof or pharmaceutically acceptable C1-C6 alkyl addition salts thereof.
    Type: Grant
    Filed: May 18, 2000
    Date of Patent: June 24, 2008
    Assignee: Teijin Limited
    Inventors: Tatsuki Shiota, Fuminori Miyagi, Takashi Kamimura, Tomohiro Ohta, Yasuhiro Takano, Hideki Horiuchi
  • Cyclic amine CCR5 receptor antagonists
    Publication number: 20070249701
    Abstract: Remedies or prophylactics for diseases in association with CCR5 such as AIDS, rheumatoid arthritis or nephritis comprising a cyclic amine compound represented by the following formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1-C6 alkyl addition salt thereof, as an active ingredient.
    Type: Application
    Filed: April 2, 2007
    Publication date: October 25, 2007
    Inventors: Tatsuki Shiota, Tomonori Yokoyama, Takashi Kamimura
  • Cycloamine ccr5 receptor antagonists
    Publication number: 20070010509
    Abstract: Remedies or prophylactics for diseases in association with CCR5 such as AIDS, rheumatoid arthritis or nephritis comprising a cyclic amine compound represented by the following formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1-C6 alkyl addition salt thereof, as an active ingredient.
    Type: Application
    Filed: December 6, 2000
    Publication date: January 11, 2007
    Inventors: Tatsuki Shiota, Tomonori Yokoyama, Takashi Kamimura
  • Diarylalkyl cyclic diamine derivatives as chemokine receptor antagonists
    Patent number: 6686353
    Abstract: Cyclic diamines of formula (I) or their pharmacologically acceptable acid addition salts, and their medical applications are described. These compounds inhibit the action of chemokines such as MIP-1a and/or MCP-1 on target cells, and are useful as a therapeutic drug and/or preventative drug in diseases, such as atherosclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissue.
    Type: Grant
    Filed: July 15, 1999
    Date of Patent: February 3, 2004
    Assignees: Teijin Intellectual Property Center Limited, Combichem, Inc.
    Inventors: Tatsuki Shiota, Shinsuke Yamagami, Kenichiro Kataoka, Noriaki Endo, Hiroko Tanaka, Doug Barnum, Jonathan Greene, Wilna Moree, Michele Ramirez Weinhouse, Christine M. Tarby
  • Cyclic amine derivatives and their use as drugs
    Patent number: 6451842
    Abstract: A compound represented by the general formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1-C6 alkyl addition salt thereof, and their medical applications. These compounds inhibit the action of chemokines such as MIP-1&agr; and/or MCP-1 on target cells, and are useful as therapeutic and/or preventative drugs in diseases, such as atherosclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissues.
    Type: Grant
    Filed: May 16, 2000
    Date of Patent: September 17, 2002
    Assignees: Dupont Pharmaceuticals Company, Teijin Limited
    Inventors: Tatsuki Shiota, Ken-ichiro Kataoka, Minoru Imai, Takaharu Tsutsumi, Masaki Sudoh, Ryo Sogawa, Takuya Morita, Takahiko Hada, Yumiko Muroga, Osami Takenouchi, Minoru Furuya, Noriaki Endo, Christine M. Tarby, Wilna Moree, Steven Teig
  • Cyclic amine derivatives and their use as drugs
    Patent number: 6410566
    Abstract: A compound represented by the general formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1-C6 alkyl addition salt thereof, and their medical applications. These compounds inhibit the action of chemokines such as MIP-1&agr; and/or MCP-1 on target cells, and are useful as therapeutic and/or preventative drugs in diseases, such as atherosclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissues.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: June 25, 2002
    Assignees: Teijin Limited, Dupont Phamaceuticals Company
    Inventors: Tatsuki Shiota, Ken-ichiro Kataoka, Minoru Imai, Takaharu Tsutsumi, Masaki Sudoh, Ryo Sogawa, Takuya Morita, Takahiko Hada, Yumiko Muroga, Osami Takenouchi, Minoru Furuya, Noriaki Endo, Christine M. Tarby, Wilna Moree, Steven Teig
  • Cyclic amine derivatives and their use as drugs
    Patent number: 6362177
    Abstract: A compound represented by the general formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1-C6 alkyl addition salt thereof, and their medical applications. These compounds inhibit the action of chemokines such as MIP-1&agr; and/or MCP-1 on target cells, and are useful as therapeutic and/or preventative drugs in diseases, such as atheroclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissues.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: March 26, 2002
    Assignees: Teijin Limited, Dupont Pharmaceuticals Research Laboratories
    Inventors: Tatsuki Shiota, Ken-ichiro Kataoka, Minoru Imai, Takaharu Tsutsumi, Masaki Sudoh, Ryo Sogawa, Takuya Morita, Takahiko Hada, Yumiko Muroga, Osami Takenouchi, Minoru Furuya, Noriaki Endo, Christine M. Tarby, Wilna Moree, Steven Teig
  • Prostaglandins and processes for production thereof
    Patent number: 5990346
    Abstract: A prostaglandin having formula (I), (II), or (III): ##STR1## a process of production thereof, and inhibitors of cell migration caused by chemokines containing (I) or (II) as an active ingredient.
    Type: Grant
    Filed: February 26, 1997
    Date of Patent: November 23, 1999
    Assignee: Teijin Limited
    Inventors: Kenichiro Kataoka, Toru Minoshima, Tatsuki Shiota, Takaharu Tsutsumi, Takahiko Hada, Hiroko Tanaka, Takuya Morita, Noriaki Endo
  • Benzopyran derivative, process for producing the same and pharmaceutical composition containing the same
    Patent number: 5574061
    Abstract: A benzopyran derivative represented by the formula (I) or its pharmaceutically acceptable salt: ##STR1## wherein either one of X and Y stands for the following formula ##STR2## and the other one of X and Y and R.sup.1 -R.sup.10 stand for various substituents,and ACAT inhibitor, anti-hyperlipidemia agent and anti-atherosclerosis agent compositions containing the same as an active ingredient.
    Type: Grant
    Filed: March 23, 1994
    Date of Patent: November 12, 1996
    Assignee: Teijin Limited
    Inventors: Tatsuki Shiota, Takumi Takeyasu, Kenichiro Kataoka, Tsutomu Mochizuki, Hirofumi Tanabe, Mikio Ota, Hisao Yamaguchi
  • Benzoxa condensed ring compounds, process for producing the same and pharmaceutical composition comprising the same
    Patent number: 5496853
    Abstract: Pharmaceutical compositions containing a benzoxazole compound and a 2,3-dihydrobenzofuran compound represented by the following formula (I) and its pharmaceutically acceptable salt: ##STR1## In the formula, any one of P, Q, R and S is a group represented by the formula: ##STR2## and R.sub.1, R.sub.2 and the reining three substituents out of the substituents P to S each independently stand for various substituents. These compositions are used as an ATCAT inhibitor or for treating hyperlipidemia and atherosclerosis.
    Type: Grant
    Filed: April 26, 1995
    Date of Patent: March 5, 1996
    Assignee: Teijin Limited
    Inventors: Tatsuki Shiota, Takumi Takeyasu, Kenichiro Kataoka, Tsutomu Mochizuki, Hirofumi Tanabe, Mikio Ota, Masatoshi Kano, Hisao Yamaguchi