Patents by Inventor Tatsuo Nakata

Tatsuo Nakata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10302925
    Abstract: To provide a microscope including: an objective optical system that condenses light from a sample; a relay optical system that relays the light condensed by the objective optical system; a photodetector detects the light coming from the objective optical system and relayed by the relay optical system; and a variable-focus optical system disposed at a position between the photodetector and the objective optical system, the position being optically conjugate to a pupil of the objective optical system, the variable-focus optical system being capable of changing a focal position of the objective optical system in a direction along an objective optical axis.
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: May 28, 2019
    Assignee: OLYMPUS CORPORATION
    Inventors: Tatsuo Nakata, Kenichi Kusaka
  • Patent number: 10281699
    Abstract: A microscope system includes an objective lens that focuses, on a specimen, illumination light produced by a light source. An illumination-area switching mechanism is disposed between the objective lens and the specimen and switches an illumination area irradiated with the illumination light focused by the objective lens among a plurality of illumination areas on the specimen that are located outside an objective optical axis of the objective lens. An inner focus lens is disposed on the objective optical axis between the light source and the objective lens and changes a focus position of the objective lens in a direction along the objective optical axis.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: May 7, 2019
    Assignee: Olympus Corporation
    Inventors: Tatsuo Nakata, Atsushi Doi, Kentaro Imoto
  • Publication number: 20180136445
    Abstract: To provide a microscope including: an objective optical system that condenses light from a sample; a relay optical system that relays the light condensed by the objective optical system; a photodetector detects the light coming from the objective optical system and relayed by the relay optical system; and a variable-focus optical system disposed at a position between the photodetector and the objective optical system, the position being optically conjugate to a pupil of the objective optical system, the variable-focus optical system being capable of changing a focal position of the objective optical system in a direction along an objective optical axis.
    Type: Application
    Filed: October 25, 2017
    Publication date: May 17, 2018
    Applicant: OLYMPUS CORPORATION
    Inventors: Tatsuo NAKATA, Kenichi KUSAKA
  • Publication number: 20180059397
    Abstract: Provided is a microscope system including: an objective lens that focuses, on a specimen, illumination light produced by a light source; an illumination-area switching mechanism that is disposed between the objective lens and the specimen and that switches an illumination area irradiated with the illumination light focused by the objective lens among a plurality of illumination areas on the specimen that are located outside the objective optical axis of the objective lens; and an inner focus lens that is disposed on the objective optical axis between the light source and the objective lens and that changes the focus position of the objective lens in the direction along the objective optical axis.
    Type: Application
    Filed: August 23, 2017
    Publication date: March 1, 2018
    Applicant: OLYMPUS CORPORATION
    Inventors: Tatsuo NAKATA, Atsushi DOI, Kentaro IMOTO
  • Publication number: 20170108683
    Abstract: A microscope includes: a light source, an objective, a varifocal optical system that is arranged on an illumination light path between the objective and the light source, a reflection optical system that deflects an illumination light axis of the illumination light toward an optical axis of the objective, and a rotator that rotates the objective and the reflection optical system around a rotation axis that is orthogonal to the optical axis of the objective.
    Type: Application
    Filed: October 13, 2016
    Publication date: April 20, 2017
    Applicant: OLYMPUS CORPORATION
    Inventors: Yuya MIYAZONO, Tatsuo NAKATA, Kenichi KUSAKA
  • Patent number: 8994806
    Abstract: A microscope apparatus organizes and stores a plurality of types of image information acquired by a plurality of image acquisition methods at different timings. The microscope apparatus includes a time counting unit for counting time, a plurality of different image acquisition units, and a storage unit for storing image information, when acquired by any one of the image acquisition units, and timing information counted by the time counting unit, by having them associated with each other. Even if the image acquisition units acquire different types of image information at different timings, the timing information can be used to call up the image information stored in the storage unit in a chronological order.
    Type: Grant
    Filed: July 1, 2010
    Date of Patent: March 31, 2015
    Assignee: Olympus Corporation
    Inventors: Mitsuhiro Nakano, Tatsuo Nakata
  • Patent number: 8730574
    Abstract: A microscope system includes a culture unit for holding and cultivating a specimen while maintaining constant temperature and humidity; a stage for holding the culture unit; a first light-converging optical system for converging illumination light emitted from a light source on the specimen; a second light-converging optical system for converging transmitted light that has passed through the specimen; a transmitted-light pinhole provided at a position optically conjugate to the light-converging position of illumination light on the specimen to cut off part of transmitted light converged by the second light-converging optical system; a transmitted-light detector that detects transmitted light that has passed through the transmitted-light pinhole; a moving system for moving the first and second light-converging optical systems, the transmitted-light pinhole, and the transmitted-light detector and the stage relative to each other; a housing that encloses these components and cuts off external light; and a contro
    Type: Grant
    Filed: November 29, 2010
    Date of Patent: May 20, 2014
    Assignee: Olympus Corporation
    Inventors: Akinori Araya, Tatsuo Nakata
  • Patent number: 8699128
    Abstract: A laser scanning microscope includes a culture vessel that accommodates a specimen and is capable of maintaining an interior temperature and humidity thereof, and an optical system space adjacent and optically connected to the culture vessel. The optical system space includes a scanner that two-dimensionally scans ultrashort pulsed laser light across the specimen; an objective lens that focuses the scanned ultrashort pulsed laser light on the specimen and collects light coming from the specimen; a dichroic mirror, disposed between the scanner and the objective lens, that splits off the light coming from the specimen from the laser light; a photodetector that detects the split-off light coming from the specimen; and an outer cover, provided so as to surround the optical system space, that blocks light coming from outside the optical system space.
    Type: Grant
    Filed: October 7, 2010
    Date of Patent: April 15, 2014
    Assignee: Olympus Corporation
    Inventors: Yusuke Yamashita, Tatsuo Nakata
  • Patent number: 8542438
    Abstract: A laser scanning microscope includes a stage that moves a sample placed thereon, a laser light source that emits laser light, a line-focus optical system that focuses the laser light into a line shape, a DMD including a plurality of movable micromirrors that are arrayed in the lengthwise direction of the line shape and that reflect the line-focused laser light, an irradiation optical system that irradiates the sample with the laser light reflected by the DMD, and a photodetector in which a plurality of channels for detecting light from the sample are arrayed in one column, wherein the DMD is driven so that a plurality of micromirrors simultaneously reflect the laser light and so that micromirrors that reflect the laser light are sequentially switched, wherein the stage moves the sample in a direction crossing the array direction of a plurality of light spots formed on the sample.
    Type: Grant
    Filed: November 18, 2010
    Date of Patent: September 24, 2013
    Assignee: Olympus Corporation
    Inventors: Tatsuo Nakata, Kosuke Takagi
  • Patent number: 8531762
    Abstract: A confocal microscope apparatus comprises a first optical scanning system which obtains a scan image of a sample using a laser beam from a first laser light source, a second optical scanning system which scans specific regions of a sample with a laser beam from a second laser light source that is different from the first laser light source, thereby causing a particular phenomenon, and a beam diameter varying mechanism which can change the beam diameter of the laser beam of at least one of the first optical scanning system and the second optical scanning system. With this configuration, the apparatus further comprises an excitation light intensity distribution calculator which calculates and stores the excitation light intensity distribution along a depth direction on the sample surface from the beam diameter of the laser beam output from the beam diameter varying mechanism.
    Type: Grant
    Filed: October 27, 2011
    Date of Patent: September 10, 2013
    Assignee: Olympus Optical Co., Ltd.
    Inventor: Tatsuo Nakata
  • Patent number: 8445865
    Abstract: A scanning microscope device includes a light source that emits laser light; an X-Y galvanometer mirror that scans the laser light on a sample; an objective lens that irradiates the sample with the scanned laser light and collects fluorescence generated at an irradiated position; a non-descan-detection excitation DM that is disposed between the X-Y galvanometer mirror and the objective lens and separates the laser light and the fluorescence from each other; a fiber that receives the separated fluorescence through an entrance end thereof and emits the fluorescence from an exit end thereof that is formed in a substantially linear shape; a diffraction grating that disperses the fluorescence emitted from the exit end of the fiber in a direction orthogonal to a longitudinal direction of the exit end; and a multi-anode PMT having plural cells arrayed in the dispersing direction of the dispersed fluorescence.
    Type: Grant
    Filed: May 21, 2010
    Date of Patent: May 21, 2013
    Assignee: Olympus Corporation
    Inventors: Hiroshi Sasaki, Tatsuo Nakata
  • Patent number: 8159663
    Abstract: To enable both observations of coherent anti-Stokes Raman scattering light and multiphoton fluorescence in a same apparatus so as to observe a specimen by various observation methods. There is provided a laser microscope apparatus comprising: two optical paths for guiding pulsed laser beams having two different frequencies whose frequency difference is approximately equal to a specific molecular vibration frequency in a specimen; a multiplexer for combining the pulsed laser beams guided through these two optical paths; and a frequency dispersion adjuster which is provided on at least one of these two optical paths, and is capable of adjustment to approximately equalize frequency dispersion quantities of the pulsed laser beams guided through the two optical paths.
    Type: Grant
    Filed: May 20, 2009
    Date of Patent: April 17, 2012
    Assignee: Olympus Corporation
    Inventors: Shinichi Takimoto, Takeshi Hashimoto, Hirokazu Kubo, Tatsuo Nakata
  • Patent number: 8154796
    Abstract: A microscope apparatus that can observe into the interior of a specimen and that can apply an optical stimulus over a wide area within a short period of time is provided. The microscope apparatus comprises at least one observation scanning optical system including a laser light source for emitting observation laser light, an objective lens, and a scanning optical system for two-dimensionally scanning the observation laser light in a predetermined examination plane of the specimen via the objective lens; and at least one stimulus optical system which includes a lamp light source for emitting light having a wavelength used for optical stimulation and which irradiates the specimen with the light emitted from the lamp light source.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: April 10, 2012
    Assignee: Olympus Corporation
    Inventors: Makoto Araki, Hiroshi Sasaki, Tatsuo Nakata, Makio Ueno
  • Patent number: 8144396
    Abstract: An image can be prevented from becoming unclear over time during long-term observation. The invention provides a microscope apparatus including a specimen container for containing a specimen; an objective lens disposed opposite the specimen container for collecting light from the specimen in the specimen container; an immersion-liquid supplying unit for supplying immersion liquid to a space between the objective lens and the specimen container; and an immersion-liquid removing unit for removing the immersion liquid from the space between the objective lens and the specimen container. The immersion-liquid removing unit includes a nozzle for ejecting compressed air to the space between the objective lens and the specimen container.
    Type: Grant
    Filed: April 2, 2008
    Date of Patent: March 27, 2012
    Assignee: Olympus Corporation
    Inventors: Masaharu Tomioka, Akinori Araya, Toshiyuki Hattori, Yasunari Matsukawa, Tatsuo Nakata
  • Publication number: 20120038980
    Abstract: A confocal microscope apparatus comprises a first optical scanning system which obtains a scan image of a sample using a laser beam from a first laser light source, a second optical scanning system which scans specific regions of a sample with a laser beam from a second laser light source that is different from the first laser light source, thereby causing a particular phenomenon, and a beam diameter varying mechanism which can change the beam diameter of the laser beam of at least one of the first optical scanning system and the second optical scanning system. With this configuration, the apparatus further comprises an excitation light intensity distribution calculator which calculates and stores the excitation light intensity distribution along a depth direction on the sample surface from the beam diameter of the laser beam output from the beam diameter varying mechanism.
    Type: Application
    Filed: October 27, 2011
    Publication date: February 16, 2012
    Applicant: OLUMPUS CORPORATION
    Inventor: Tatsuo NAKATA
  • Patent number: 8072680
    Abstract: A microscope apparatus includes a first optical system which illuminates a sample via an objective lens with light output from a light source and which detects fluorescence emitted from the sample via the objective lens, and a second optical scanning system which irradiates specific regions of the sample with a laser beam output from a laser light source, thereby causing a particular phenomenon. The first optical system may include a rotatable disk to obtain a confocal effect, and the light output from the light source scans the sample via the rotatable disk, and the fluorescence is detected via the rotatable disk. A depth position of a focal plane of the second optical scanning system is generally the same as a depth position of a focal plane of the first optical system.
    Type: Grant
    Filed: January 19, 2010
    Date of Patent: December 6, 2011
    Assignee: Olympus Optical Co., Ltd.
    Inventor: Tatsuo Nakata
  • Patent number: 7983466
    Abstract: The invention provides a microscope apparatus, used for identifying the cell phases of a plurality of cells mounted on a stage, including an analysis/observation optical system used for acquiring an observed-image of the cells and a stimulus optical system used for applying an optical stimulus to prescribed cells. Using these optical systems, the cell phases of the cells mounted on the stage are identified, an optical stimulus is applied to the cells, and the state of the cells before and after applying the stimulus is observed.
    Type: Grant
    Filed: May 4, 2007
    Date of Patent: July 19, 2011
    Assignee: Olympus Corporation
    Inventors: Mitsuhiro Nakano, Tatsuo Nakata
  • Patent number: 7969653
    Abstract: It is possible to achieve a required field number and numerical aperture for microscope observation at a scanning speed equal to video-rate or higher and also to change the scanning speed with a simple configuration. The invention provides a laser microscope including a laser light source; a scanning unit configured to scan a specimen with laser light emitted from the laser light source; and an objective lens configured to focus the laser light scanned by the scanning unit on the specimen. The scanning unit is provided with an electro-optical deflecting element including an electro-optical crystal in which a refractive index gradient is induced by injecting electric current.
    Type: Grant
    Filed: December 17, 2007
    Date of Patent: June 28, 2011
    Assignee: Olympus Corporation
    Inventors: Akinori Araya, Tatsuo Nakata, Makio Ueno
  • Publication number: 20110134516
    Abstract: Disclosed herein is a microscope system.
    Type: Application
    Filed: November 29, 2010
    Publication date: June 9, 2011
    Applicant: OLYMPUS CORPORATION
    Inventors: Akinori ARAYA, Tatsuo Nakata
  • Publication number: 20110121198
    Abstract: Provided is a laser scanning microscope with which it is possible to reduce the time required for scanning and to detect light from a sample with high sensitivity.
    Type: Application
    Filed: November 18, 2010
    Publication date: May 26, 2011
    Applicant: OLYMPUS CORPORATION
    Inventors: Tatsuo Nakata, Kosuke TAKAGI