Patents by Inventor Tatsushi Oka

Tatsushi Oka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Semi-synthesis of human insulin
    Patent number: 4511505
    Abstract: A process for preparing a B30-threonine-insulin which comprising reacting a des-B30-insulin with an excess amount of threonine derivative in the presence of an enzyme specifically acting on the basic-amino-acid carbonyl in peptide bondings.
    Type: Grant
    Filed: June 3, 1983
    Date of Patent: April 16, 1985
    Assignee: Shionogi & Co., Ltd.
    Inventors: Kazuyuki Morihara, Tatsushi Oka, Hiroshige Tsuzuki
  • Semi-synthesis of human insulin
    Patent number: 4401757
    Abstract: A process for preparing B30-threonine-insulin which comprising reacting a des-B30-insulin with an excess amount of threonine derivative in the presence of an enzyme specifically acting on a lysine carbonyl in peptide bondings and produced by Achromobacter lyticus M 497-1.
    Type: Grant
    Filed: December 31, 1981
    Date of Patent: August 30, 1983
    Assignee: Shionogi & Co., Ltd.
    Inventors: Kazuyuki Morihara, Tatsushi Oka, Masami Soejima, Takeharu Masaki
  • Semi-synthesis of human insulin
    Patent number: 4400465
    Abstract: A process for preparing a B30-threonine-insulin which comprising reacting a des-B30-insulin with an excess amount of threonine derivative in the presence of an enzyme specifically acting on the basic-amino-acid carbonyl in peptide bondings.
    Type: Grant
    Filed: December 31, 1981
    Date of Patent: August 23, 1983
    Assignee: Shionogi & Co., Ltd.
    Inventors: Kazuyuki Morihara, Tatsushi Oka, Hiroshige Tsuzuki
  • Semi-synthesis of human insulin
    Patent number: 4320196
    Abstract: A process for preparing a B30-threonine-insulin which comprising reacting a des-B30-insulin with an excess amount of threonine derivative in the presence of an enzyme specifically acting on the basic-amino-acid carbonyl in peptide bondings.
    Type: Grant
    Filed: April 9, 1980
    Date of Patent: March 16, 1982
    Assignee: Shionogi & Co., Ltd.
    Inventors: Kazuyuki Morihara, Tatsushi Oka, Hiroshige Tsuzuki
  • Semi-synthesis of human insulin
    Patent number: 4320197
    Abstract: A process for preparing a B30-threonine-insulin which comprising reacting a des-B30-insulin with an excess amount of threonine derivative in the presence of an enzyme specifically acting on a lysine carbonyl in peptide bondings and produced by Achromobacter lyticus M 497-1.
    Type: Grant
    Filed: April 9, 1980
    Date of Patent: March 16, 1982
    Assignee: Shionogi & Co., Ltd.
    Inventors: Kazuyuki Morihara, Tatsushi Oka, Masami Soejima, Takeharu Masaki