Patents by Inventor Tatyana S. Levchenko

Tatyana S. Levchenko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and methods for targeted immune system delivery
    Patent number: 9962448
    Abstract: Compounds and methods for targeted immune system delivery are disclosed. Pharmaceutical compositions including the disclosed compounds and a pharmaceutically acceptable excipient are also disclosed. Methods of targeted delivery to an antigen-presenting cell, and methods of treating or preventing a disease or condition susceptible to treatment by immunomodulation are disclosed.
    Type: Grant
    Filed: October 4, 2013
    Date of Patent: May 8, 2018
    Assignees: Northeastern University, National Institute of Agricultural Technology, University of Padova
    Inventors: Juan Sebastian Pappalardo, Micaela Toniutti, Stefano Salmaso, Tatyana S. Levchenko, Vladimir Torchilin
  • Compounds and Methods for Targeted Immune System Delivery
    Publication number: 20150238621
    Abstract: Compounds and methods for targeted immune system delivery are disclosed. Pharmaceutical compositions including the disclosed compounds and a pharmaceutically acceptable excipient are also disclosed. Methods of targeted delivery to an antigen-presenting cell, and methods of treating or preventing a disease or condition susceptible to treatment by immunomodulation are disclosed.
    Type: Application
    Filed: October 4, 2013
    Publication date: August 27, 2015
    Applicant: Northeastern University
    Inventors: Juan Sabastian PAPPALARDO, Micaela TONIUTTI, Stefano SALMASO, Tatyana S. LEVCHENKO, Vladimir TORCHILIN
  • MIXED MICELLES INCLUDING AMPHIPATHIC CONJUGATES OF RNA AGENTS, AND USES THEREOF
    Publication number: 20110008395
    Abstract: Disclosed are improved pharmaceutical formulations for the delivery of RNA interference agents, such as antisense RNA, micro-RNA and siRNA. The formulations employ mixed micelles including amphipathic conjugates of the iRNA agents and amphipathic micelle-forming molecules with extended hydrophilic chains. Also disclosed are methods of using the pharmaceutical formulations to increase delivery of an iRNA agent to an intracellular target, and to decrease extracellular nuclease degradation of an iRNA agent in the formulations.
    Type: Application
    Filed: July 7, 2008
    Publication date: January 13, 2011
    Inventors: Vladimir Torchilin, Tatyana S. Levchenko