Patents by Inventor Taura L. Barr

Taura L. Barr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPUTER IMPLEMENTED DISCOVERY OF ANTIBODY SIGNATURES
    Publication number: 20200402609
    Abstract: Disclosed herein are computer implemented methods of distinguishing ischemic stroke, hemorrhagic stroke, and stroke mimic by detecting circulating biomarkers in a subject. Also provided herein are systems, kits, and methods for the detecting.
    Type: Application
    Filed: February 21, 2019
    Publication date: December 24, 2020
    Inventors: Taura L. Barr, Grant O'Connell
  • COMPUTER IMPLEMENTED DISCOVERY OF BIOMARKERS FOR BLOOD BRAIN BARRIER DISRUPTION
    Publication number: 20190311789
    Abstract: Provided herein are computer implemented methods of evaluating, detecting, and identifying biomarkers of blood brain barrier disruption. Also provided herein are kits and methods for detecting blood brain barrier disruption in a subject.
    Type: Application
    Filed: October 3, 2017
    Publication date: October 10, 2019
    Inventors: Taura L. BARR, Grant O'CONNELL
  • MARKERS OF STROKE AND STROKE SEVERITY
    Publication number: 20190017117
    Abstract: Provided herein are methods, kits, and devices for detecting ischemic stroke and identifying biomarkers of ischemic stroke. Evaluating the expression patterns of ischemic stroke biomarkers in biological samples can allow for the diagnosis of stroke in a time-sensitive and bedside manner.
    Type: Application
    Filed: July 8, 2016
    Publication date: January 17, 2019
    Inventors: Taura L. BARR, Richard GIERSCH, Grant O'CONNELL
  • Biomarkers for acute ischemic stroke
    Patent number: 9200322
    Abstract: The present invention provides methods and compositions for the diagnosis of acute ischemic stroke. The invention further provides methods and compositions for distinguishing acute ischemic stroke from other forms of stroke and TIAs and “stroke mimic” events. Moreover, methods and compositions are provided to facilitate the treatment of acute ischemic stroke patients.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: December 1, 2015
    Assignees: The United States of America, as Represented by the Secretary, Department of Health and Human Services, University of Pittsburgh—of the Commonwealth System of Higher Education
    Inventors: Taura L. Barr, Maria Del Mar Matarin, Steven Jay Warach, Andrew Barry Singleton, Yvette P. Conley
  • BIOMARKER ALGORITHM FOR DETERMINING THE TIME OF STROKE SYMPTOM ONSET AND METHOD
    Publication number: 20140221235
    Abstract: A method of determining the time of stroke symptom onset is provided including obtaining a biological sample from an individual; contacting the biological sample with a detection composition comprising at least one expression mediator of a LY96, ARG1, CA4, and a TLR expression mediators, or a combination of these expression mediators, wherein at least one of the expression mediators is associated with an acute phase response of ischemic stroke, for forming a detectable response; and correlating the detectable response with a time of onset of one or more stroke symptoms. A composition is provided having a nucleic acid probe, an antibody, or a purified biomarker that is specific for at least one of a LY96, ARG1, CA4, and TLR expression mediators, or a combination of these expression mediators.
    Type: Application
    Filed: January 29, 2014
    Publication date: August 7, 2014
    Applicant: WEST VIRGINIA UNIVERSITY
    Inventor: Taura L. Barr
  • BIOMARKERS FOR ACUTE ISCHEMIC STROKE
    Publication number: 20130189243
    Abstract: The present invention provides methods and compositions for the diagnosis of acute ischemic stroke. The invention further provides methods and compositions for distinguishing acute ischemic stroke from other forms of stroke and TIAs and “stroke mimic” events. Moreover, methods and compositions are provided to facilitate the treatment of acute ischemic stroke patients.
    Type: Application
    Filed: February 22, 2011
    Publication date: July 25, 2013
    Inventors: Taura L. Barr, Maria Del Mar Matarin, Steven Jay Warach, Andrew Barry Singleton, Yvette P. Conley