Abstract: Single-stranded oligonucleotide probes, systems, kits and methods for chromosome enumeration, gene copy enumeration, or tissue diagnostics. The probes are particularly suited for detecting gene amplification, deletion, or rearrangement in tissue samples in a single, dual, or multiplexed assay. The probes exhibit improved performance compared to industry leading dual-stranded probes; particularly in terms of the rate of hybridization.

Abstract: A fluid injection system includes a fluid injector assembly; a fluid conditioning module having an outlet port that is fluidly coupled to an inlet port of the fluid injector assembly; an injector assembly outlet conduit fluidly coupled to an outlet port of the fluid injector assembly and disposed downstream of the fluid injector assembly, the injector assembly outlet conduit defining a pressure measurement port and a flow-restricting orifice, the pressure measurement port being disposed upstream of the flow-restricting orifice along the direction of fluid flow through the fluid injector assembly; a pressure sensor fluidly coupled to the pressure measurement port; and a controller operatively coupled to the fluid conditioning module and the pressure sensor. The controller is configured to adjust a flowrate of a fluid through the injector assembly inlet conduit based on a pressure signal from the pressure sensor.

Abstract: A fluid injection system includes a fluid injector assembly; a fluid conditioning module having an outlet port that is fluidly coupled to an inlet port of the fluid injector assembly; an injector assembly outlet conduit fluidly coupled to an outlet port of the fluid injector assembly and disposed downstream of the fluid injector assembly, the injector assembly outlet conduit defining a pressure measurement port and a flow-restricting orifice, the pressure measurement port being disposed upstream of the flow-restricting orifice along the direction of fluid flow through the fluid injector assembly; a pressure sensor fluidly coupled to the pressure measurement port; and a controller operatively coupled to the fluid conditioning module and the pressure sensor. The controller is configured to adjust a flowrate of a fluid through the injector assembly inlet conduit based on a pressure signal from the pressure sensor.

Abstract: Described herein are embodiments performed by a computing device capable of having a first display and a second display. The device may also execute a windowing system. Arbitrary applications execute on the computing device. Each such application has a corresponding application window managed by the windowing system. A start-projecting request may be received from an arbitrary one of the applications, and the windowing system may respond to the start request by generating, displaying, and managing a projection window. The application may generate and display content via the projection window. Responsive to the start-projecting request, display information about the first display and the second display may be used by the windowing system to display the projection window. A stop-projecting request from the application may cause the windowing system to terminate the projection window.