Patents by Inventor Tea SHAVLAKADZE

Tea SHAVLAKADZE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RAPAMYCIN DERIVATIVES
    Publication number: 20220242878
    Abstract: The disclosure relates to compounds of formula (I) and pharmaceutically acceptable salts, and compositions thereof, wherein the substituents are as defined herein. Also provided are methods of making compounds of formula (I), and methods involving the compounds or compositions for treating disorders and diseases described herein.
    Type: Application
    Filed: October 12, 2021
    Publication date: August 4, 2022
    Inventors: Simone BONAZZI, Michael CONNOLLY, David Jonathan GLASS, Manuel MIHALIC, Andrew William PATTERSON, Silvio ROGGO, Tea SHAVLAKADZE
  • ISOTHIAZOLIDINE 1,1-DIOXIDE AND 1,4-BUTAN SULTONE CONTAINING RAPAMYCIN DERIVATIVES AND USES THEREOF
    Publication number: 20220202787
    Abstract: Described herein are compounds of Formula (I) that are inhibitors of mTORC1, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.
    Type: Application
    Filed: March 25, 2020
    Publication date: June 30, 2022
    Inventors: Simone Bonazzi, Michael Connolly, David Jonathan Glass, Andrew W. Patterson, Tea Shavlakadze
  • RAPAMYCIN DERIVATIVES
    Publication number: 20220064185
    Abstract: The disclosure provides 32-deoxo-rapamycin derivatives of Formula (I), or a pharmaceutically acceptable salt thereof, pharmaceutical compositions and pharmaceutical combinations comprising a compound of Formula (I), and methods of making same. Also provided herein are methods of using a compound of Formula (I) or a pharmaceutically acceptable salt thereof for treating the diseases and disorders described herein.
    Type: Application
    Filed: December 17, 2019
    Publication date: March 3, 2022
    Inventors: Simone Bonazzi, Michael Connolly, David Jonathan Glass, Manuel Mihalic, Andrew W. Patterson, Silvio Roggo, Tea Shavlakadze, Patrik Zueger
  • NOVEL RAPAMYCIN DERIVATIVES
    Publication number: 20200392159
    Abstract: The disclosure relates to compounds of formula (I) and pharmaceutically acceptable salts, and compositions thereof, wherein the substituents are as defined herein. Also provided are methods of making compounds of formula (I), and methods involving the compounds or compositions for treating disorders and diseases described herein.
    Type: Application
    Filed: August 27, 2020
    Publication date: December 17, 2020
    Inventors: Simone BONAZZI, Michael CONNOLLY, David Jonathan GLASS, Manuel MIHALIC, Andrew William PATTERSON, Silvio ROGGO, Tea SHAVLAKADZE
  • Rapamycin derivatives
    Patent number: 10800793
    Abstract: The disclosure relates to compounds of formula (I) and pharmaceutically acceptable salts, and compositions thereof, wherein the substituents are as defined herein. Also provided are methods of making compounds of formula (I), and methods involving the compounds or compositions for treating disorders and diseases described herein.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: October 13, 2020
    Assignee: NOVARTIS AG
    Inventors: Simone Bonazzi, Michael Connolly, David Jonathan Glass, Manuel Mihalic, Andrew William Patterson, Silvio Roggo, Tea Shavlakadze
  • NOVEL RAPAMYCIN DERIVATIVES
    Publication number: 20190092788
    Abstract: The disclosure relates to compounds of formula (I) and pharmaceutically acceptable salts, and compositions thereof, wherein the substituents are as defined herein. Also provided are methods of making compounds of formula (I), and methods involving the compounds or compositions for treating disorders and diseases described herein.
    Type: Application
    Filed: September 25, 2018
    Publication date: March 28, 2019
    Inventors: Simone BONAZZI, Michael CONNOLLY, David Jonathan GLASS, Manuel MIHALIC, Andrew William PATTERSON, Silvio ROGGO, Tea SHAVLAKADZE