Patents by Inventor Ted Dawson

Ted Dawson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DETECTION OF PAR IN THE CSF OF PATIENTS WITH PARKINSON'S DISEASE
    Publication number: 20230176041
    Abstract: Poly(ADP-ribose) (PAR) is a protein implicated in numerous neurodegenerative disease states including Parkinson's disease (PD). To date, no routine laboratory test has been developed to diagnosis, assess or monitor patients suffering from PD. Disclosed herein a novel method to assess the PAR concentration in the cerebral spinal fluid (CSF) of a patient and correlate that concentration to the medical condition of a patient with PD. Also disclosed is the use of PAR as a biomarker for PD.
    Type: Application
    Filed: October 26, 2022
    Publication date: June 8, 2023
    Inventors: Ted Dawson, Valina Dawson, Tae-In Kam, Liana Rosenthal, Shaida Andrabi
  • DETECTION OF PAR IN THE CSF OF PATIENTS WITH PARKINSON'S DISEASE
    Publication number: 20210148898
    Abstract: Poly(ADP-ribose) (PAR) is a protein implicated in numerous neurodegenerative disease states including Parkinson's disease (PD). To date, no routine laboratory test has been developed to diagnosis, assess or monitor patients suffering from PD. Disclosed herein a novel method to assess the PAR concentration in the cerebral spinal fluid (CSF) of a patient and correlate that concentration to the medical condition of a patient with PD. Also disclosed is the use of PAR as a biomarker for PD.
    Type: Application
    Filed: June 1, 2018
    Publication date: May 20, 2021
    Inventors: Ted Dawson, Valina Dawson, Tae-In Kam, Liana Rosenthal, Shaida Andrabi
  • Inhibitors of rotamase enzyme activity
    Publication number: 20030114365
    Abstract: This invention relates to the method of using neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration.
    Type: Application
    Filed: August 27, 2002
    Publication date: June 19, 2003
    Applicant: GPI NIL Holding, Inc.
    Inventors: Joseph P. Steiner, Solomon Snyder, Gregory S. Hamilton, Ted Dawson
  • Inhibitors of rotamase enzyme activity
    Patent number: 6500843
    Abstract: This invention relates to the method of using neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration.
    Type: Grant
    Filed: November 5, 1999
    Date of Patent: December 31, 2002
    Assignees: GPI NIL Holdings, Inc., Johns Hopkins University School of Medicine
    Inventors: Joseph P. Steiner, Solomon Snyder, Gregory S. Hamilton, Ted Dawson
  • INHIBITORS OF ROTAMASE ENZYME ACTIVITY
    Publication number: 20020052372
    Abstract: This invention relates to the method of using neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration.
    Type: Application
    Filed: November 5, 1999
    Publication date: May 2, 2002
    Inventors: JOSEPH P. STEINER, SOLOMON SNYDER, GREGORY S. HAMILTON, TED DAWSON
  • Inhibitors of rotamase enzyme activity
    Patent number: 6022878
    Abstract: This invention relates to the method of using neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration.
    Type: Grant
    Filed: July 10, 1998
    Date of Patent: February 8, 2000
    Assignees: GPI NIL Holdings, Inc., John Hopkins University School of Medicine
    Inventors: Joseph P. Steiner, Solomon Snyder, Gregory S. Hamilton, Ted Dawson
  • Inhibitors of rotamase enzyme activity
    Patent number: 5846981
    Abstract: This invention relates to the method of using neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration.
    Type: Grant
    Filed: January 23, 1997
    Date of Patent: December 8, 1998
    Assignees: GPI NIL Holdings Inc., Johns Hopkins University School of Medicine
    Inventors: Joseph P. Steiner, Solomon Snyder, Gregory S. Hamilton, Ted Dawson
  • Inhibitors of rotamase enzyme activity
    Patent number: 5843960
    Abstract: This invention relates to the method of using neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration.
    Type: Grant
    Filed: January 23, 1997
    Date of Patent: December 1, 1998
    Assignees: GPI Nil Holdings, Inc., Johns Hopkins University School of Medicine
    Inventors: Joseph P. Steiner, Solomon Snyder, Gregory S. Hamilton, Ted Dawson
  • Inhibitors of rotamase enzyme activity
    Patent number: 5798355
    Abstract: This invention relates to the method of using neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 25, 1998
    Assignees: GPI NIL Holdings, Inc., Johns Hopkins University School of Medicine
    Inventors: Joseph P. Steiner, Solomon Snyder, Gregory S. Hamilton, Ted Dawson