Patents by Inventor Ted DINAN

Ted DINAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • for treating obesity and weight management
    Patent number: 11833178
    Abstract: A strain of Bifidobacterium longum APC 1472 is described. The strain has weight lowering effects in-vivo, achieved through inducing satiety via decreased internalisation of the Ghrelin receptor, and therefore, decreased constitutive activity. Moreover, the strain also showed a trend towards decreased ghrelin receptor hypothalamic expression in HFD-fed mice when compared with vehicle control group. The strain also improves glucose tolerance and decreased insulin plasma levels in mice, indicating the strain in the prevention and/or treatment of Type II diabetes, especially in obese individuals.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: December 5, 2023
    Assignees: UNIVERSITY COLLEGE CORK—NATIONAL UNIVERSITY OF IRELAND, CORK, AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC)
    Inventors: John Cryan, Ted Dinan, Catherine Stanton, Harriet Schellekens, Cristina Torres, Bernard Roy
  • COMPOSITIONS COMPRISING BACTERIAL STRAINS
    Publication number: 20230158083
    Abstract: The invention provides a composition comprising a bacterial strain of the genus Megasphaera, for use in stimulating the immune system in subject.
    Type: Application
    Filed: June 23, 2022
    Publication date: May 25, 2023
    Inventors: Imke ELISABETH MULDER, Parthena Fotiadou, Amy Beth Holt, Suaad Ahmed, Anna Ettorre, Samantha Yuille, Ted Dinan, John Cryan
  • COMPOSITIONS COMPRISING BACTERIAL STRAINS
    Publication number: 20230135434
    Abstract: The invention provides compositions comprising a bacterial strain of the genus Fusicatenibacter and their use in medicine.
    Type: Application
    Filed: May 19, 2022
    Publication date: May 4, 2023
    Inventors: Imke Elisabeth MULDER, Nicole REICHARDT, Helene SAVIGNAC, Sasha CHETAL, Ted DINAN, John CRYAN
  • COMPOSITIONS COMPRISING BACTERIAL STRAINS
    Publication number: 20220265733
    Abstract: The invention provides pharmaceutical compositions comprising bacteria and the use of such compositions in the treatment of disease.
    Type: Application
    Filed: December 17, 2021
    Publication date: August 25, 2022
    Inventors: Imke Elisabeth MULDER, Nicole REICHARDT, Helene SAVIGNAC, Sasha CHETAL, Ted DINAN, John CRYAN, Samantha YUILLE
  • Compositions comprising bacterial strains
    Patent number: 11419902
    Abstract: The invention provides a composition comprising a bacterial strain of the genus Megasphaera, for use in stimulating the immune system in subject.
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: August 23, 2022
    Assignee: 4D Pharma Research Limited
    Inventors: Imke Elisabeth Mulder, Parthena Fotiadou, Amy Beth Holt, Suaad Ahmed, Anna Ettorre, Samantha Yuille, Ted Dinan, John Cryan
  • Compositions comprising bacterial strains
    Patent number: 11376284
    Abstract: The invention provides compositions comprising bacterial strains for treating and preventing central nervous system disorders and conditions.
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: July 5, 2022
    Assignee: 4D Pharma Research Limited
    Inventors: Helene Savignac, Imke Elisabeth Mulder, Alexander James Stevenson, Ted Dinan, John Cryan
  • COMPOSITIONS COMPRISING BACTERIAL STRAINS
    Publication number: 20220184145
    Abstract: The invention provides compositions comprising bacterial strains for treating and preventing central nervous system disorders and conditions.
    Type: Application
    Filed: November 19, 2021
    Publication date: June 16, 2022
    Inventors: Helene SAVIGNAC, Imke Elisabeth MULDER, Alexander James STEVENSON, Ted DINAN, John CRYAN
  • COMPOSITIONS COMPRISING BACTERIAL STRAINS
    Publication number: 20210361722
    Abstract: The invention provides a composition comprising a bacterial strain of the genus Megasphaera, for use in the treatment or prevention of a disorder characterised by serotonin deficiency.
    Type: Application
    Filed: June 9, 2021
    Publication date: November 25, 2021
    Inventors: Imke ELISABETH MULDER, Anna ETTORRE, Suaad AHMED, John CRYAN, Ted DINAN
  • COMPOSITIONS COMPRISING BACTERIAL STRAINS
    Publication number: 20210275605
    Abstract: The invention provides a composition comprising a bacterial strain of the genus Megasphaera, for use in the treatment or prevention of an autoimmune or inflammatory disorder or cancer
    Type: Application
    Filed: November 11, 2020
    Publication date: September 9, 2021
    Inventors: Imke Elisabeth MULDER, Suaad AHMED, Anna ETTORRE, Sarah Anne REID, Ted DINAN, John CRYAN
  • COMPOSITIONS COMPRISING BACTERIAL STRAINS
    Publication number: 20210052671
    Abstract: The invention provides a composition comprising a bacterial strain of the genus Megasphaera, for use in stimulating the immune system in subject.
    Type: Application
    Filed: September 4, 2020
    Publication date: February 25, 2021
    Inventors: Imke Elisabeth MULDER, Parthena FOTIADOU, Amy Beth HOLT, Suaad AHMED, Anna ETTORRE, Samantha YUILLE, Ted DINAN, John CRYAN
  • NEW USE OF MICROBIOLOGICAL COMPOSITIONS
    Publication number: 20200405787
    Abstract: The present invention provides a pharmaceutical composition comprising dead cells of Lactobacillus strains useful for the protection of subjects against the development of conditions with behavioral, psychological and/or physical components caused or exacerbated by stress or anxiety, and/or useful in treating existing conditions with behavioral, psychological and/or physical components caused or exacerbated by stress or anxiety. Examples of specific conditions include stress, anxiety, depression, mood disturbances, sociability disorders, irritable bowel syndrome, autism, autism spectrum disorder, post-traumatic stress disorder, chronic stress and a range of other stress-related diseases.
    Type: Application
    Filed: March 22, 2019
    Publication date: December 31, 2020
    Inventors: Colin HILL, Ted DINAN, Alicja WARDA, Stephen PERRETT
  • BIFIDOBACTERIUM LONGUM FOR TREATING OBESITY AND WEIGHT MANAGEMENT
    Publication number: 20200281992
    Abstract: A strain of Bifidobacterium longum APC 1472 is described. The strain has weight lowering effects in-vivo, achieved through inducing satiety via decreased internalisation of the Ghrelin receptor, and therefore, decreased constitutive activity. Moreover, the strain also showed a trend towards decreased ghrelin receptor hypothalamic expression in HFD-fed mice when compared with vehicle control group. The strain also improves glucose tolerance and decreased insulin plasma levels in mice, indicating the strain in the prevention and/or treatment of Type II diabetes, especially in obese individuals.
    Type: Application
    Filed: August 27, 2018
    Publication date: September 10, 2020
    Inventors: John CRYAN, Ted DINAN, Catherine STANTON, Harriet Schellekens, Cristina TORRES, Roy BERNARD
  • COMPOSITIONS COMPRISING BACTERIAL STRAINS
    Publication number: 20200121756
    Abstract: The invention provides compositions comprising bacterial strains for treating and preventing central nervous system disorders and conditions.
    Type: Application
    Filed: November 22, 2019
    Publication date: April 23, 2020
    Inventors: Helene Myriam SAVIGNAC, Imke Elisabeth MULDER, Ted DINAN, John CRYAN
  • COMPOSITIONS COMPRISING BACTERIAL STRAINS
    Publication number: 20200078417
    Abstract: The invention provides compositions comprising bacterial strains for treating and preventing central nervous system disorders and conditions.
    Type: Application
    Filed: November 22, 2019
    Publication date: March 12, 2020
    Inventors: Helene SAVIGNAC, Imke Elisabeth MULDER, Alexander James STEVENSON, Ted DINAN, John CRYAN