Patents by Inventor Ted P. McDonald

Ted P. McDonald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for treating thrombocytopenia
    Patent number: 5593666
    Abstract: A method and composition utilizing thrombopoietin for increasing platelet cell counts in thrombocytopenia is disclosed. The method and composition are suitable for treatments of patients suffering from medical conditions, such as HIV/AIDS or chemotherapy, which result in low platelet cell numbers. Also disclosed are the active moieties or domains of the thrombopoietin molecule.
    Type: Grant
    Filed: October 27, 1994
    Date of Patent: January 14, 1997
    Assignee: The University of Tennessee Research Corp.
    Inventor: Ted P. McDonald
  • Polypeptide and a method for its production
    Patent number: 5128449
    Abstract: The present invention provides for a new polypeptide and a method for producing the same. The polypeptide has a molecular weight of approximately 30,000 daltons as a dimer and a monomer molecular weight of about 15,000 daltons, an isoelectric pH of about 4.47 and an activity of at least 21,000 units per milligram of protein in the monomer or dimer state. The preferred method comprises chromatographing a crude polypeptide-containing medium on a dextran derived chromatography column; precipitating the eluate in a water-ethanol solution; electrophoresing the precipitate in a polyacrylamide gel; and chromatographing the extract on a reverse phase-high performance liquid chromatography column.
    Type: Grant
    Filed: July 5, 1988
    Date of Patent: July 7, 1992
    Assignee: The University of Tennessee Research Corporation
    Inventor: Ted P. McDonald