Patents by Inventor Teemu T. Junttila

Teemu T. Junttila has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BISPECIFIC ANTIGEN-BINDING MOLECULES AND METHODS OF USE
    Publication number: 20240092906
    Abstract: The present invention provides bispecific antigen-binding molecules having a monovalent arm specific to a first target antigen (e.g., a T cell antigen, such as CD3) and a bivalent arm specific for a second target antigen (e.g., a tumor antigen, such as HER2). Bispecific antigen-binding molecules are useful in the treatment of disorders, such as cancer (e.g., HER2-positive cancer). The invention also features methods of producing bispecific antigen-binding molecules, methods of treating disorders using bispecific antigen-binding molecules, and compositions including bispecific antigen-binding molecules.
    Type: Application
    Filed: November 22, 2023
    Publication date: March 21, 2024
    Inventors: Diego ELLERMAN, Teemu T. Junttila, Twyla Noelle Lombana, Dionysos Slaga, Christoph Spiess
  • Bispecific antigen-binding molecules and methods of use
    Patent number: 11866498
    Abstract: The present invention provides bispecific antigen-binding molecules having a monovalent arm specific to a first target antigen (e.g., a T cell antigen, such as CD3) and a bivalent arm specific for a second target antigen (e.g., a tumor antigen, such as HER2). Bispecific antigen-binding molecules are useful in the treatment of disorders, such as cancer (e.g., HER2-positive cancer). The invention also features methods of producing bispecific antigen-binding molecules, methods of treating disorders using bispecific antigen-binding molecules, and compositions including bispecific antigen-binding molecules.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: January 9, 2024
    Assignee: Genentech, Inc.
    Inventors: Diego Ellerman, Teemu T. Junttila, Twyla Noelle Lombana, Dionysos Slaga, Christoph Spiess
  • Anti-CD3 antibodies and methods of use
    Patent number: 11732054
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: August 22, 2023
    Assignee: Genentech, Inc.
    Inventors: Xiaocheng Chen, Mark S. Dennis, Allen J. Ebens, Jr., Teemu T. Junttila, Robert F. Kelley, Mary A. Mathieu
  • ANTI-FCRH5 ANTIBODIES
    Publication number: 20230096941
    Abstract: The invention provides anti-FcRH5 antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: May 2, 2022
    Publication date: March 30, 2023
    Inventors: Allen J. EBENS, Meredith C. HAZEN, Jo-Anne HONGO, Jennifer W. JOHNSTON, Teemu T. JUNTTILA, Ji LI, Andrew G. POLSON
  • Anti-CD3 antibodies and methods of use
    Patent number: 11530275
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: December 20, 2022
    Assignee: Genentech, Inc.
    Inventors: Xiaocheng Chen, Mark S. Dennis, Allen J. Ebens, Jr., Teemu T. Junttila, Robert F. Kelley, Mary A. Mathieu
  • Anti-FCRH5 antibodies
    Patent number: 11352431
    Abstract: The invention provides anti-FcRH5 antibodies and immunoconjugates and methods of using the same.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: June 7, 2022
    Assignee: Genentech, Inc.
    Inventors: Allen J. Ebens, Meredith C. Hazen, Jo-Anne Hongo, Jennifer W. Johnston, Teemu T. Junttila, Ji Li, Andrew G. Polson
  • TREATMENT OF CANCER WITH HER2XCD3 BISPECIFIC ANTIBODIES IN COMBINATION WITH ANTI-HER2 MAB
    Publication number: 20220098325
    Abstract: The present invention provides methods of treating of HER2-positive cancers (such as HER2-positive breast cancer and HER2-positive gastric cancers) using HER2 antibodies, such as a combination of a HER2 T cell-dependent bispecific antibody (TDB) with an additional HER2 antibody (e.g., trastuzumab).
    Type: Application
    Filed: September 13, 2021
    Publication date: March 31, 2022
    Inventors: Teemu T. JUNTTILA, Stuart LUTZKER
  • HUMANIZED AND AFFINITY MATURED ANTIBODIES TO FcRH5 AND METHODS OF USE
    Publication number: 20220048993
    Abstract: The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.
    Type: Application
    Filed: October 29, 2021
    Publication date: February 17, 2022
    Inventors: Isidro HOTZEL, Teemu T. JUNTTILA, Ji LI, Justin SCHEER, Danielle DICARA, Diego ELLERMAN, Christoph SPIESS, Paul J. CARTER
  • Humanized and affinity matured antibodies to FcRH5 and methods of use
    Patent number: 11192950
    Abstract: The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: December 7, 2021
    Assignee: Genentech, Inc.
    Inventors: Isidro Hotzel, Teemu T. Junttila, Ji Li, Justin Scheer, Danielle Dicara, Diego Ellerman, Christoph Spiess, Paul J. Carter
  • ANTI-CD3 ANTIBODIES AND METHODS OF USE
    Publication number: 20200299409
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Application
    Filed: February 13, 2020
    Publication date: September 24, 2020
    Inventors: Xiaocheng CHEN, Mark S. DENNIS, Allen J. EBENS, Jr., Teemu T. JUNTTILA, Robert F. KELLEY, Mary A. MATHIEU
  • ANTI-CD3 ANTIBODIES AND METHODS OF USE
    Publication number: 20200299408
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Application
    Filed: February 13, 2020
    Publication date: September 24, 2020
    Inventors: Xiaocheng CHEN, Mark S. DENNIS, Allen J. EBENS, JR., Teemu T. JUNTTILA, Robert F. KELLEY, Mary A. MATHIEU
  • ANTI-FCRH5 ANTIBODIES
    Publication number: 20200190185
    Abstract: The invention provides anti-FcRH5 antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: September 26, 2019
    Publication date: June 18, 2020
    Inventors: Allen J. EBENS, Meredith C. HAZEN, Jo-Anne HONGO, Jennifer W. JOHNSTON, Teemu T. JUNTTILA, Ji LI, Andrew G. POLSON
  • Anti-CD3 antibodies and methods of use
    Patent number: 10640572
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: May 5, 2020
    Assignee: Genentech, Inc.
    Inventors: Xiaocheng Chen, Mark S. Dennis, Allen J. Ebens, Jr., Teemu T. Junttila, Robert F. Kelley, Mary A. Mathieu
  • HUMANIZED AND AFFINITY MATURED ANTIBODIES TO FcRH5 AND METHODS OF USE
    Publication number: 20190315860
    Abstract: The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.
    Type: Application
    Filed: April 25, 2019
    Publication date: October 17, 2019
    Inventors: Isidro HOTZEL, Teemu T. JUNTTILA, Ji LI, Justin SCHEER, Danielle DICARA, Diego ELLERMAN, Christoph SPIESS, Paul J. CARTER
  • Anti-FcRH5 antibodies
    Patent number: 10435471
    Abstract: The invention provides anti-FcRH5 antibodies and immunoconjugates and methods of using the same.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: October 8, 2019
    Assignee: Genentech, Inc.
    Inventors: Allen J. Ebens, Meredith C. Hazen, Jo-Anne Hongo, Jennifer W. Johnston, Teemu T. Junttila, Ji Li, Andrew G. Polson
  • BISPECIFIC ANTIGEN-BINDING MOLECULES AND METHODS OF USE
    Publication number: 20190270814
    Abstract: The present invention provides bispecific antigen-binding molecules having a monovalent arm specific to a first target antigen (e.g., a T cell antigen, such as CD3) and a bivalent arm specific for a second target antigen (e.g., a tumor antigen, such as HER2). Bispecific antigen-binding molecules are useful in the treatment of disorders, such as cancer (e.g., HER2-positive cancer). The invention also features methods of producing bispecific antigen-binding molecules, methods of treating disorders using bispecific antigen-binding molecules, and compositions including bispecific antigen-binding molecules.
    Type: Application
    Filed: February 8, 2019
    Publication date: September 5, 2019
    Inventors: Diego ELLERMAN, Teemu T. JUNTTILA, Twyla Noelle LOMBANA, Dionysos SLAGA, Christoph SPIESS
  • Humanized and affinity matured antibodies to FcRH5 and methods of use
    Patent number: 10323094
    Abstract: The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: June 18, 2019
    Assignee: Genentech, Inc.
    Inventors: Isidro Hotzel, Teemu T. Junttila, Ji Li, Justin Scheer, Danielle DiCara, Diego Ellerman, Christoph Spiess, Paul J. Carter
  • ANTI-CD3 ANTIBODIES AND METHODS OF USE
    Publication number: 20190112389
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Application
    Filed: September 27, 2018
    Publication date: April 18, 2019
    Inventors: Xiaocheng CHEN, Mark S. DENNIS, Allen J. EBENS, JR., Teemu T. JUNTTILA, Robert F. KELLEY, Mary A. MATHIEU, Liping L. SUN
  • ANTI-CD3 ANTIBODIES AND METHODS OF USE
    Publication number: 20190016823
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Application
    Filed: September 27, 2018
    Publication date: January 17, 2019
    Inventors: Xiaocheng CHEN, Mark S. DENNIS, Allen J. EBENS, JR., Teemu T. JUNTTILA, Robert F. KELLEY, Mary A. MATHIEU, Liping L. SUN
  • ANTI-CD3 ANTIBODIES AND METHODS OF USE
    Publication number: 20170204194
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Application
    Filed: March 29, 2017
    Publication date: July 20, 2017
    Inventors: Xiaocheng CHEN, Mark S. DENNIS, Allen J. EBENS, Jr., Teemu T. JUNTTILA, Robert F. KELLEY, Mary A. MATHIEU