Patents by Inventor Teigo Sakakibara

Teigo Sakakibara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240118207
    Abstract: To provide a method and kit for measurement of a target substance with high detection sensitivity, provided is a method of measuring at least any one of the presence or absence, and a concentration, of a target substance in a sample liquid, the method including the steps of: (a) preparing a first particle that specifically binds to the target substance and contains a rare earth complex, and a second particle that has a larger average particle diameter than that of the first particle and specifically binds to the target substance; (b) mixing the sample liquid, the first particle, and the second particle to provide a mixed liquid; and (c) determining at least any one of the presence or absence, and the concentration, of the target substance from polarization anisotropy of the mixed liquid obtained in the step (b).
    Type: Application
    Filed: December 1, 2023
    Publication date: April 11, 2024
    Inventors: NORISHIGE KAKEGAWA, TAKAHIRO MASUMURA, TEIGO SAKAKIBARA, IKUO NAKAJIMA, FUMIO YAMAUCHI, KENGO KANAZAKI
  • Publication number: 20240093087
    Abstract: Provided is a particle having high detection sensitivity in the detection of a substance to be measured, such as an antigen or an antibody, from a body. The particle includes a rare earth complex, wherein the particle has a particle size distribution of 0.1 or less in terms of polydispersity index (pdi) measured by dynamic light scattering, and wherein the particle has a hydrophilic polymer on a surface thereof.
    Type: Application
    Filed: November 29, 2023
    Publication date: March 21, 2024
    Inventors: NORISHIGE KAKEGAWA, TAKAHIRO MASUMURA, TEIGO SAKAKIBARA, IKUO NAKAJIMA, FUMIO YAMAUCHI, KENGO KANAZAKI
  • Patent number: 11925918
    Abstract: A silica aggregate includes primary silica particles aggregated, the primary silica particles having an average particle size of 1 nm or more and less than 10 nm, the primary silica particles being crosslinked to each other by a bond containing a siloxane bond.
    Type: Grant
    Filed: March 26, 2020
    Date of Patent: March 12, 2024
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Kengo Kanazaki, Fumio Yamauchi, Teigo Sakakibara, Yoshinori Kotani, Ryoko Ueyama
  • Publication number: 20230366826
    Abstract: To perform measurement based on polarization anisotropy in which a reaction between a target substance and a luminescent reagent is performed within a short period of time, and in which high-sensitivity measurement can be performed, provided is an analysis method including measuring a value (R) for polarization anisotropy through use of a luminescent reagent that reacts with a target substance, to thereby determine at least any one of the presence or absence of the target substance and a concentration of the target substance, the analysis method including: a reaction step of mixing a sample containing the target substance with the luminescent reagent, and subjecting the mixture to a reaction to obtain a reaction liquid; a dilution step of diluting the reaction liquid to obtain a diluted liquid; and a measurement step of measuring the R of the diluted liquid, the luminescent reagent including luminescent particles.
    Type: Application
    Filed: May 2, 2023
    Publication date: November 16, 2023
    Inventors: NORISHIGE KAKEGAWA, TAKAHIRO MASUMURA, FUMIO YAMAUCHI, KENGO KANAZAKI, TOMOHIRO NAKAMURA, IKUO NAKAJIMA, TEIGO SAKAKIBARA
  • Publication number: 20230366818
    Abstract: Provided are a reagent and a measurement method for enabling a specimen test based on polarization anisotropy to be performed with high sensitivity and within a short period of time. Specifically, provided is an analysis method including measuring a value (R) for polarization anisotropy through use of a luminescent reagent that binds with a target substance, the analysis method including: a reaction step including mixing a sample containing the target substance with the luminescent reagent and a sensitizer, and subjecting the mixture to a reaction to obtain a reaction liquid; and a measurement step of measuring the R of the reaction liquid, the luminescent reagent including a luminescent particle substrate and a hydrophilic layer arranged on an outside of the luminescent particle substrate, the sensitizer containing a hydrophilic polymer.
    Type: Application
    Filed: May 1, 2023
    Publication date: November 16, 2023
    Inventors: NORISHIGE KAKEGAWA, TAKAHIRO MASUMURA, FUMIO YAMAUCHI, KENGO KANAZAKI, TOMOHIRO NAKAMURA, IKUO NAKAJIMA, TEIGO SAKAKIBARA
  • Patent number: 11633715
    Abstract: A DNA complex includes a carrier and DNA immobilized on the carrier. 80% or more by mass of the DNA is single-stranded DNA, the DNA has an average molecular weight of 500,000 or less, and the DNA content is more than 15% by mass and 50% or less by mass of the DNA complex. The carrier contains an inorganic material. The DNA complex has an average particle size of 10 ?m or more.
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: April 25, 2023
    Assignee: Canon Kabushiki Kaisha
    Inventors: Fumio Yamauchi, Kengo Kanazaki, Teigo Sakakibara, Yoshinori Kotani, Ryoko Ueyama
  • Publication number: 20200230573
    Abstract: A silica aggregate includes primary silica particles aggregated, the primary silica particles having an average particle size of 1 nm or more and less than 10 nm, the primary silica particles being crosslinked to each other by a bond containing a siloxane bond.
    Type: Application
    Filed: March 26, 2020
    Publication date: July 23, 2020
    Inventors: Kengo Kanazaki, Fumio Yamauchi, Teigo Sakakibara, Yoshinori Kotani, Ryoko Ueyama
  • Publication number: 20200222877
    Abstract: A DNA complex includes a carrier and DNA immobilized on the carrier. 80% or more by mass of the DNA is single-stranded DNA, the DNA has an average molecular weight of 500,000 or less, and the DNA content is more than 15% by mass and 50% or less by mass of the DNA complex. The carrier contains an inorganic material. The DNA complex has an average particle size of 10 ?m or more.
    Type: Application
    Filed: March 25, 2020
    Publication date: July 16, 2020
    Inventors: Fumio Yamauchi, Kengo Kanazaki, Teigo Sakakibara, Yoshinori Kotani, Ryoko Ueyama
  • Patent number: 9227897
    Abstract: A coating liquid including a fluorine-containing organic magnesium compound represented by the following chemical formula (1), a method for manufacturing an optical component having an optical film obtained from the coating liquid, and a photographic optical system are disclosed: Mg(OR11)(OR22)??Chemical formula (1) where R11 represents an alkyl group that may have a substituent group having 1 or more and 6 or less carbon atoms having at least a fluorine atom, R22 represents an alkyl group that may have a substituent group having 1 or more and 6 or less carbon atoms that may have a fluorine atom, or an aromatic cyclic group that may have a substituent group, and R11 is different from R22.
    Type: Grant
    Filed: June 20, 2011
    Date of Patent: January 5, 2016
    Assignee: Canon Kabushiki Kaisha
    Inventors: Hiroyuki Tanaka, Motokazu Kobayashi, Teigo Sakakibara
  • Patent number: 9079214
    Abstract: A method of producing a magnesium fluoride coating includes a step of forming a coating by applying a solution containing a fluorine-containing organic magnesium compound represented by the following formula to a base and a step of heat-treating the coating while the coating is being irradiated with a beam of light with a wavelength of 246 nm or less: Mg(CF3—X—COO)2??(1) wherein X represents a single bond or one of —(CF2)n—, —(CH2)m—, and —CH2CF2— that may have a substituent, where n and m each represent an integer of 1 to 4. The temperature of the heat-treating step can be 250° C. or lower. The coating can be irradiated with a beam of light with a wavelength of 185 nm or less.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: July 14, 2015
    Assignee: Canon Kabushiki Kaisha
    Inventors: Hiroyuki Tanaka, Motokazu Kobayashi, Teigo Sakakibara
  • Patent number: 8741383
    Abstract: Provided is a method of producing an optical film which has an excellent strength and a low refractive index, and can be used for an optical antireflective film. The production method includes preparing a coating liquid including a capsule having a shell of a halogenated compound of an element of Group 2 by forming an emulsion of one of an aqueous solution including a compound containing an element of Group 2 and an aqueous solution including a compound containing a halogen, and an organic solvent, applying the coating liquid on a substrate, and heating the coating liquid, thereby forming an optical film containing a hollow particle having the shell of a halogenated compound of an element of Group 2.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: June 3, 2014
    Assignee: Canon Kabushiki Kaisha
    Inventors: Motokazu Kobayashi, Hiroyuki Tanaka, Teigo Sakakibara
  • Patent number: 8674163
    Abstract: A DNA hybrid which comprises a porous oxide matrix and DNA immobilized thereon, and is useful for environmental clean-up, where the hybrid is prepared by removing a dispersion medium from a dispersion of colloidal oxide and DNA.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: March 18, 2014
    Assignee: Canon Kabushiki Kaisha
    Inventors: Zuyi Zhang, Teigo Sakakibara, Yoshinori Kotani, Norio Nishi
  • Publication number: 20130094090
    Abstract: A coating liquid including a fluorine-containing organic magnesium compound represented by the following chemical formula (1), a method for manufacturing an optical component having an optical film obtained from the coating liquid, and a photographic optical system are disclosed: Mg(OR11)(OR22) ??Chemical formula (1) where R11 represents an alkyl group that may have a substituent group having 1 or more and 6 or less carbon atoms having at least a fluorine atom, R22 represents an alkyl group that may have a substituent group having 1 or more and 6 or less carbon atoms that may have a fluorine atom, or an aromatic cyclic group that may have a substituent group, and R11 is different from R22.
    Type: Application
    Filed: June 6, 2011
    Publication date: April 18, 2013
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Hiroyuki Tanaka, Motokazu Kobayashi, Teigo Sakakibara
  • Patent number: 8399069
    Abstract: A method of producing a magnesium fluoride coating includes a step of forming a coating by applying a solution containing a fluorine-containing organic magnesium compound represented by the following formula to a base and a step of heat-treating the coating while the coating is being irradiated with a beam of light with a wavelength of 246 nm or less: Mg(CF3—X—COO)2??(1) wherein X represents a single bond or one of —(CF2)n—, —(CH2)m—, and —CH2CF2— that may have a substituent, where n and m each represent an integer of 1 to 4. The temperature of the heat-treating step can be 250° C. or lower. The coating can be irradiated with a beam of light with a wavelength of 185 nm or less.
    Type: Grant
    Filed: July 26, 2010
    Date of Patent: March 19, 2013
    Assignee: Canon Kabushiki Kaisha
    Inventors: Hiroyuki Tanaka, Motokazu Kobayashi, Teigo Sakakibara
  • Publication number: 20110027577
    Abstract: A method of producing a magnesium fluoride coating includes a step of forming a coating by applying a solution containing a fluorine-containing organic magnesium compound represented by the following formula to a base and a step of heat-treating the coating while the coating is being irradiated with a beam of light with a wavelength of 246 nm or less: Mg(CF3—X—COO)2??(1) wherein X represents a single bond or one of —(CF2)n—, —(CH2)m—, and —CH2CF2— that may have a substituent, where n and m each represent an integer of 1 to 4. The temperature of the heat-treating step can be 250° C. or lower. The coating can be irradiated with a beam of light with a wavelength of 185 nm or less.
    Type: Application
    Filed: July 26, 2010
    Publication date: February 3, 2011
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Hiroyuki Tanaka, Motokazu Kobayashi, Teigo Sakakibara
  • Publication number: 20100255189
    Abstract: Provided is a method of producing an optical film which has an excellent strength and a low refractive index, and can be used for an optical antireflective film. The production method includes preparing a coating liquid including a capsule having a shell of a halogenated compound of an element of Group 2 by forming an emulsion of one of an aqueous solution including a compound containing an element of Group 2 and an aqueous solution including a compound containing a halogen, and an organic solvent, applying the coating liquid on a substrate, and heating the coating liquid, thereby forming an optical film containing a hollow particle having the shell of a halogenated compound of an element of Group 2.
    Type: Application
    Filed: March 31, 2010
    Publication date: October 7, 2010
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Motokazu Kobayashi, Hiroyuki Tanaka, Teigo Sakakibara
  • Patent number: 7642295
    Abstract: An electrolyte membrane made of a phosphate-containing siloxane-based polymer for fuel cell, where the polymer comprises a siloxane backbone and a poly(meth)acrylate chain to which phosphate groups are attached, and the polymer is formed by vinyl polymerization of a silane compound having a (meth)acrylate functional group or a hydrolysis-polycondensation product thereof and a (meth)acrylate compound having a phosphate group, followed by siloxane crosslinking. The electrolyte membrane of a siloxane-based polymer has a high conductivity for a fuel cell.
    Type: Grant
    Filed: June 8, 2004
    Date of Patent: January 5, 2010
    Assignee: Canon Kabushiki Kaisha
    Inventors: Zuyi Zhang, Teigo Sakakibara, Motokazu Kobayashi, Masayuki Yamada, Shinji Eritate, Iko Ito, Yoshio Kanzaki
  • Patent number: 7615630
    Abstract: Provided is a solubility-controallable compound being soluble in a solvent due to a solvent-philic group thereof, of which solubility in the solvent is irreversibly lowered when the group is removed by retro-Diels-Alder reaction.
    Type: Grant
    Filed: May 8, 2006
    Date of Patent: November 10, 2009
    Assignee: Canon Kabushiki Kaisha
    Inventors: Takayuki Ishikawa, Teigo Sakakibara, Daisuke Miura, Hidemitsu Uno, Noboru Ono
  • Publication number: 20090042077
    Abstract: There are provided a polymer electrolyte membrane having at least one surface with an average surface roughness Ra? of from 30 nm to 500 nm and a surface area ratio Sr of 1.2 or more in which Sr is defined as S/S0 with S0 representing a surface area when the at least one surface is ideally flat and S representing an actual surface area of the at least one surface, and a polymer electrolyte fuel cell comprising the polymer electrolyte membrane. Thereby, a polymer electrolyte fuel cell is provided that improves the efficiency of contact between the polymer electrolyte membrane and the catalyst, efficiently separates hydrogen ions and electrons produced on the catalyst, and provides high output characteristics.
    Type: Application
    Filed: October 9, 2008
    Publication date: February 12, 2009
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Motokazu Kobayashi, Masayuki Yamada, Zuyi Zhang, Shinji Eritate, Teigo Sakakibara
  • Publication number: 20080176227
    Abstract: Provided are a DNA carrier where DNA is firmly held in a substrate, which can reduce the elution of DNA into water and can take full advantage of the capability of DNA to selectively and specifically collect a substance; and a method of producing the DNA carrier. Also provided is a collection system using DNA, which can be used in the high-accuracy detection of a particular substance and in an environmental cleanup capable of efficiently removing a substance, in which the DNA carrier is used to collect the substance contained in air or water by taking full advantage of the capability of DNA to selectively and specifically collect the substance. The DNA carrier is one where DNA is held in a porous matrix containing polyorganosiloxane with a basic functional group and particles. Preferably, the polyorganosiloxane with a basic functional group contains a hydrolysis condensate of one or more of particular silane compounds with an amino group.
    Type: Application
    Filed: July 13, 2005
    Publication date: July 24, 2008
    Applicant: Canon Kabushiki Kaisha
    Inventors: Zuyi Zhang, Teigo Sakakibara, Yoshinori Kotani, Kazuyuki Matsumura, Norio Nishi