Patents by Inventor Teiji Kishimoto

Teiji Kishimoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,2,3,4-Tetrahydroisoquinolines 6.10,7,8 dihydroxy substitute-1-methylanilino and use as smooth muscle relaxants
    Patent number: 4447436
    Abstract: 1,2,3,4-Tetrahydroisoquinolines having the formula: ##STR1## wherein R.sub.1 and R.sub.2 are each hydrogen, lower alkyl, lower alkenyl, acyl, aryl or ar(lower)alkyl, in which aryl and the aryl moiety of the ar(lower)alkyl may contain at least one substituent selected from the group consisting of halogen, lower alkoxy, amino, nitro, hydroxy, acyloxy, ar(lower)alkoxy, lower alkylenedioxy, halo(lower)alkyl, acylamino, ar(lower)alkylamino and aryl, and pharmaceutically acceptable salts thereof, having a relaxant activity on smooth muscles.
    Type: Grant
    Filed: January 4, 1980
    Date of Patent: May 8, 1984
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Teiji Kishimoto, Hiromu Kochi, Masayuki Kato
  • 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof
    Patent number: 4370332
    Abstract: A 1,2,3,4-tetrahydroisoquinoline having smooth muscle relaxant activity of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are each hydrogen or lower alkyl, R.sub.3 is phenyl having substituents selected from the group consisting of lower alkenyloxy, mercapto, lower alkylthio, sulfamoyl and mono or disubstituted sulfamoyl, or a heterocyclic group, R.sub.4 and R.sub.5 are each hydroxy or protected hydroxy and X is --O-- or--S--.
    Type: Grant
    Filed: October 29, 1980
    Date of Patent: January 25, 1983
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Teiji Kishimoto, Hiromu Kochi, Yoshiyuki Kaneda
  • 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof
    Patent number: 4292320
    Abstract: A 1,2,3,4-tetrahydroisoquinoline having smooth muscle relaxant activity of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are each hydrogen or lower alkyl and X is --O-- or --S--, and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: August 17, 1979
    Date of Patent: September 29, 1981
    Assignee: Fujisawa Pharmaceutical Company, Limited
    Inventors: Teiji Kishimoto, Hiromu Kochi, Yoshiyuki Kaneda
  • 1,2,3,4-Tetrahydroisoquinolines and the preparation thereof
    Patent number: 4220647
    Abstract: 1,2,3,4-tetrahydroisoquinolines have the formula: ##STR1## wherein R.sub.1 and R.sub.2 are each hydrogen, lower alkyl, lower alkenyl, acyl, aryl or ar(lower)alkyl, in which aryl and the aryl moiety of the ar(lower)alkyl may contain at least one substituent selected from the group consisting of halogen, lower alkoxy, amino, nitro, hydroxy, acyloxy, ar(lower)alkoxy, lower alkylenedioxy, halo(lower)alkyl, acylamino, ar(lower)alkylamino and aryl, and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: November 5, 1975
    Date of Patent: September 2, 1980
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Teiji Kishimoto, Hiromu Kochi, Masayuki Kato
  • 1,2,3,4-Tetrahydroisoquinolines and the preparation thereof
    Patent number: 4096263
    Abstract: 1,2,3,4-Tetrahydroisoquinolines of the formula ##STR1## wherein R is a heterocyclic group which may have appropriate substituent(s) and pharmaceutically acceptable salts thereof, which have relaxing activity on smooth muscle, are disclosed, together with a method for their preparation.
    Type: Grant
    Filed: July 21, 1976
    Date of Patent: June 20, 1978
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Teiji Kishimoto, Ikuo Ueda, Masayuki Kato
  • 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof
    Patent number: 3978063
    Abstract: A 1,2,3,4-tetrahydroisoquinoline having the formula: ##SPC1##Which has relaxing activity on smooth muscles.
    Type: Grant
    Filed: July 19, 1974
    Date of Patent: August 31, 1976
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Teiji Kishimoto, Hiromu Kochi, Yoshiyuki Kaneda
  • 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof
    Patent number: 3963725
    Abstract: The present invention relates to new 1,2,3,4-tetrahydroisoquinoline derivatives, which have relaxing activity on smooth muscles. The present invention also relates to the preparation of new and known 1,2,3,4-tetraydroisoquinoline derivatives.
    Type: Grant
    Filed: July 19, 1974
    Date of Patent: June 15, 1976
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Teiji Kishimoto, Yoshiyuki Kaneda