Abstract: Disclosed herein are compositions comprising: 4-phenylbutyrate (PBA) or a pharmaceutically acceptable salt thereof in an effective concentration as a therapeutic or prophylactic agent against viral infections, e.g., herpes simplex vims (HSV) infections. Also provided are methods for treating a disease or disorder in a subject, such as a viral infection (e.g., HSV infection), comprising administering to the subject a therapeutically or prophylactically effective amount of 4-phenylbutyrate (PBA) or a pharmaceutically acceptable salt thereof.

Abstract: The present disclosure relates to compositions and drug delivery systems comprising highly porous activated carbon (HPAC) and a therapeutic agent and methods of treating a disorder using these compositions and drug delivery systems. The present disclosure also provides for methods of treating viral infections with HPAC or therapeutic agents adsorbed within HPAC and methods of eliciting an immune response comprising administering a live, live-attenuated virus or virion adsorbed to HPAC.