Abstract: Disclosed are novel omega conotoxin peptides effective in producing analgesia.

Abstract: A method of producing analgesia and enhancing opiate analgesia is disclosed. The method includes administering TVIA (SNX-185) or MVIIA (SNX-111) omega-conopeptide, or derivative thereof which is characterized by its ability to (a) inhibit voltage-gated calcium channels selectively in neuronal tissue, as evidenced by the peptide's ability to inhibit electrically stimulated contraction of the guinea pig ileum, and (b) bind to omega-conopeptide MVIIA binding sites present in neuronal tissue.

Abstract: A technique for generating a carry, AND, OR, NAND, NOR, INVERTING logic and sum and carry: operation in a one or at most two device delay by employing negative differential resistance devices. Circuits implemented with this technique are not only extremely fast, but use a small number of active devices as well. This technique could be implemented in building circuits using any transistor Bipolar Transistors, Field Effect Transistors (FETs), High Electron Mobility Transistors (HEMTs), Hetero-junction Bipolar Transistors (HBTs), etc. The negative differential resistance characteristics of the resonant tunneling transistor can be exploited to increase the noise margin. Resonant tunneling devices have the added advantage of working at very high speeds, and could yield propagation delays less than 5ps.