Patents by Inventor Teng-Kuang Yeh

Teng-Kuang Yeh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CDGSH iron sulfur domain 2 activators and use thereof
    Patent number: 11827629
    Abstract: Isoindoline compounds and their pharmaceutical compositions. Also provided are methods of treating a Cisd2-insufficiency associated disorder and protecting against doxorubicin-induced cardiotoxicity.
    Type: Grant
    Filed: May 25, 2022
    Date of Patent: November 28, 2023
    Assignees: National Health Research Institutes, National Yang Ming Chiao Tung University
    Inventors: Ting-Fen Tsai, Jinq-Chyi Lee, Teng-Kuang Yeh
  • METHODS OF INCREASING CELL PHAGOCYTOSIS
    Publication number: 20230097801
    Abstract: Disclosed are methods for treatments of conditions involving CD47 upregulation using a compound of formula (I): Variables R1-R9, X, and Het are defined therein. Also disclosed are methods for increasing phagocytosis of a cell using such a compound and pharmaceutical compositions each containing the compound and an anti-cancer agent.
    Type: Application
    Filed: June 1, 2022
    Publication date: March 30, 2023
    Inventors: Chih-Hao Chen, Wan-Ching Yen, Teng-Kuang Yeh, Chiung-Tong Chen, Hwei-Jiung Wang, Kai-Fa Huang
  • CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF
    Publication number: 20220411418
    Abstract: Isoindoline compounds and their pharmaceutical compositions. Also provided are methods of treating a Cisd2-insufficiency associated disorder and protecting against doxorubicin-induced cardiotoxicity.
    Type: Application
    Filed: May 25, 2022
    Publication date: December 29, 2022
    Inventors: Ting-Fen Tsai, Jinq-Chyi Lee, Teng-Kuang Yeh
  • Imidazol-4-one and imidazole-4-thione compounds
    Patent number: 8354442
    Abstract: Imidazol-4-one or imidazole-4-thione compounds of formula (I): wherein X, R1, R2, R3, R4, R5, and R6 are defined herein. Also disclosed is a method for treating a cannabinoid receptor-mediated disorder with these compounds.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: January 15, 2013
    Assignee: National Health Research Institutes
    Inventors: Kak-Shan Shia, Chien-Huang Wu, Teng-Kuang Yeh, Yu-Sheng Chao
  • Formulations of indol-3-yl-2-oxoacetamide compounds
    Patent number: 8026271
    Abstract: This invention relates to an oral formulation containing an effective amount of the compound of the following formula I: d-alpha-tocopheryl polyethylene glycol 1000 succinate (“TPGS”); and 2-(2-ethoxyethoxy)ethanol (“Transcutol”). R1 through R4 and n are defined herein. Also disclosed is a method of treating cancer by administering this formula to a subject orally.
    Type: Grant
    Filed: July 11, 2008
    Date of Patent: September 27, 2011
    Assignee: National Health Research Institutes
    Inventors: Teng-Kuang Yeh, Chiung-Tong Chen, Yu-Sheng Chao
  • Imidazol-4-one and Imidazole-4-thione Compounds
    Publication number: 20100113546
    Abstract: Imidazol-4-one or imidazole-4-thione compounds of formula (I): wherein X, R1, R2, R3, R4, R5, and R6 are defined herein. Also disclosed is a method for treating a cannabinoid receptor-mediated disorder with these compounds.
    Type: Application
    Filed: October 30, 2009
    Publication date: May 6, 2010
    Applicant: National Health Research Institutes
    Inventors: Kak-Shan Shia, Chien-Huang Wu, Teng-Kuang Yeh, Yu-Sheng Chao
  • ANTICANCER ORAL FORMULATION
    Publication number: 20100010059
    Abstract: This invention relates to an oral formulation containing an effective amount of the compound of the following formula I: d-alpha-tocopheryl polyethylene glycol 1000 succinate (“TPGS”); and 2-(2-ethoxyethoxy)ethanol (“Transcutol”). R1 through R4 and n are defined herein. Also disclosed is a method of treating cancer by administering this formula to a subject orally.
    Type: Application
    Filed: July 11, 2008
    Publication date: January 14, 2010
    Applicant: National Health Research Institutes
    Inventors: Teng-Kuang Yeh, Chiung-Tong Chen, Yu-Sheng Chao