Patents by Inventor Teng-Wen Li

Teng-Wen Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8961928
    Abstract: A ligand and a metal complex having the ligand are provided. The ligand and a paramagnetic metal ion form a metal complex with high stability, high relaxivity and high biocompatibility. The metal complex of the present invention is applicable to the preparation of MRI contrast agents for detecting atherosclerosis. The MRI contrast agent includes a peptide sequence specific to a matrix metalloprotease, and can be recognized by a pathological thrombocyte to target a specific site, so as to enhance the imaging contrast.
    Type: Grant
    Filed: May 9, 2012
    Date of Patent: February 24, 2015
    Assignee: National Chiao Tung University
    Inventors: Yun-Ming Wang, Gin-Chung Liu, Chiao-Yun Chen, Teng-Wen Li
  • Publication number: 20130303728
    Abstract: A ligand and a metal complex having the ligand are provided. The ligand and a paramagnetic metal ion form a metal complex with high stability, high relaxivity and high biocompatibility. The metal complex of the present invention is applicable to the preparation of MRI contrast agents for detecting atherosclerosis. The MRI contrast agent includes a peptide sequence specific to a matrix metalloprotease, and can be recognized by a pathological thrombocyte to target a specific site, so as to enhance the imaging contrast.
    Type: Application
    Filed: May 9, 2012
    Publication date: November 14, 2013
    Applicant: NATIONAL CHIAO TUNG UNIVERSITY
    Inventors: Yun-Ming Wang, Gin-Chung Liu, Chiao-Yun Chen, Teng-Wen Li