Patents by Inventor Teodor Doru Brumeanu

Teodor Doru Brumeanu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF USING MULTIVALENT MHC CLASS II-PEPTIDE CHIMERAS
    Publication number: 20080311133
    Abstract: The present invention provides a multimeric complex of at least two chimeric molecules, wherein the chimeric molecules comprise an immunoglobulin constant region element and two MHC elements wherein each MHC element is associated with a peptide, and wherein the chimeric molecules are covalently linked through a carbohydrate residue of the immunoglobulin constant region element by a polyalkylene glycol linker. Methods of making and using the multimeric complexes are also provided.
    Type: Application
    Filed: July 30, 2007
    Publication date: December 18, 2008
    Applicant: MOUNT SINAI SCHOOL OF MEDICINE
    Inventors: Teodor Doru Brumeanu, Sofia Casares, Constantin A. Bona
  • Methods of using multivalent MHC class II-peptide chimeras
    Publication number: 20040258697
    Abstract: The present invention provides a multimeric complex of at least two chimeric molecules, wherein the chimeric molecules comprise an immunoglobulin constant region element and two MHC elements wherein each MHC element is associated with a peptide, and wherein the chimeric molecules are covalently linked through a carbohydrate residue of the immunoglobulin constant region element by a polyalkylene glycol linker. Methods of making and using the multimeric complexes are also provided.
    Type: Application
    Filed: February 24, 2004
    Publication date: December 23, 2004
    Applicant: MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY
    Inventors: Teodor Doru Brumeanu, Sofia Casares, Constantin A. Bona
  • Multivalent MHC class II—peptide chimeras
    Patent number: 6811785
    Abstract: The present invention provides a multimeric complex of at least two chimeric molecules, wherein the chimeric molecules comprise an immunoglobulin constant region element and two MHC elements wherein each MHC element is associated with a peptide, and wherein the chimeric molecules are covalently linked through a carbohydrate residue of the immunoglobulin constant region element by a polyalkylene glycol linker. Methods of making and using the multimeric complexes are also provided.
    Type: Grant
    Filed: May 7, 2001
    Date of Patent: November 2, 2004
    Assignee: Mount Sinai School of Medicine of New York University
    Inventors: Teodor Doru Brumeanu, Sofia Casares, Constantin A. Bona
  • Multivalent MHC class II - peptide chimeras
    Publication number: 20020164340
    Abstract: The present invention provides a multimeric complex of at least two chimeric molecules, wherein the chimeric molecules comprise an immunoglobulin constant region element and two MHC elements wherein each MHC element is associated with a peptide, and wherein the chimeric molecules are covalently linked through a carbohydrate residue of the immunoglobulin constant region element by a polyalkylene glycol linker. Methods of making and using the multimeric complexes are also provided.
    Type: Application
    Filed: May 7, 2001
    Publication date: November 7, 2002
    Applicant: MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY OF NEW YORK
    Inventors: Teodor Doru Brumeanu, Sofia Casares, Constantin A. Bona