Abstract: For training for and performance of LGE analysis, multi-task machine-learning model is trained to output various cardiac tissue characteristics based on input of LGE MR data. The use of segmentation may be avoided or limited, resulting in a greater number of available training data samples, by using radiology clinical reports with LGE information as a source for samples. The multi-task model may be trained to output cardiac tissue characteristics using radiology clinical reports with LGE information with no segmentation or with segmentation for only a subset of the training samples. By training for multiple tasks, the accuracy of prediction for each task benefits from the information for other tasks. The trained model outputs values of characteristics for multiple tasks, such as extent of enhancement, type of enhancement, and localization of enhancement. Other tasks may be included, such as disease classification. Other inputs may be used, such as also including sensor data and/or cardiac motion.

Abstract: A neural network system for retraining operational neural networks using a synthetic data set generated by a synthetic data generator neural network is provided. The synthetic data generator network comprises an input layer for receiving an input data set; an output layer for outputting the synthetic data set; and a loss function for receiving from each operational network a value of a medical metric. The operational networks each comprise an input layer for receiving the synthetic data set; and an output layer for outputting the value of the medical metric. The synthetic data generator network is trained for generating the synthetic data set based on the loss function comprising a difference of the values of the medical metric. Each operational network is retrained using the synthetic data set.

Abstract: Techniques of training an image-synthesis ML algorithm are disclosed. The image-synthesis ML algorithm can be used to generate synthetic imaging data. The synthetic imaging data can be used, in turn, to train a further ML algorithm. The further ML algorithm may be configured to perform image-processing tasks on the respective imaging data.