Patents by Inventor Teodozyj Kolasa

Teodozyj Kolasa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
    Publication number: 20090023789
    Abstract: The present application relates to isothiazolylidene containing compounds of Formula (I) wherein R1, R2, R3, R4, and L are as defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: April 10, 2008
    Publication date: January 22, 2009
    Applicant: Abbott Laboratories
    Inventors: William A. Carroll, Michael J. Dart, Teodozyj Kolasa, Tongmei Li, Derek W. Nelson, Meena V. Patel, Sridhar Peddi, Arturo Perez-Medrano, Xueqing Wang
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
    Publication number: 20080242654
    Abstract: The present application relates to thiazolylidene containing compounds of formula (I) wherein R1, R2, R3, R4, L2 and A are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
    Type: Application
    Filed: March 19, 2008
    Publication date: October 2, 2008
    Applicant: ABBOTT LABORATORIES
    Inventors: Teodozyj Kolasa, Jennifer M. Frost, Meena V. Patel, Steven P. Latshaw, Arturo Perez-Medrano, Xueqing Wang, Sridhar Peddi, William A. Carroll, Michael J. Dart
  • Benzimidazoles that are useful in treating sexual dysfunction
    Patent number: 7351828
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
    Type: Grant
    Filed: October 31, 2003
    Date of Patent: April 1, 2008
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Pramila A. Bhatia, Jerome F. Daanen, Andrew O. Stewart, Meena V. Patel, Teodozyj Kolasa, Jorge D. Brioni, Jeffrey Rohde
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF
    Publication number: 20080064699
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, R3, R4, and L2, are defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: May 31, 2007
    Publication date: March 13, 2008
    Inventors: Alan Florjancic, Michael Dart, Keith Ryther, Arturo Perez-Medrano, William Carroll, Meena Patel, Karin Tietje, Tongmei Li, Teodozyj Kolasa, Megan Gallagher, Sridhar Peddi, Jennifer Frost, Derek Nelson
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF
    Publication number: 20080058335
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, R3, and L1 are defined in the specfication, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. The present invention also relates to compounds of formula (II), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1a, R2a and (Rx)n are as defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: May 30, 2007
    Publication date: March 6, 2008
    Inventors: Alan Florjancic, Michael Dart, Keith Ryther, Arturo Perez-Medrano, William Carroll, Meena Patel, Karin Tietje, Tongmei Li, Teodozyj Kolasa, Megan Gallagher, Sridhar Peddi, Jennifer Frost, Derek Nelson
  • Use of selective dopamine D4 receptor agonists for treating sexual dysfunction
    Publication number: 20060276484
    Abstract: The present invention relates to the use of selective dopamine D4 receptor agonists and to compositions containing selective dopamine D4 receptor agonists for the treatment of sexual dysfunction.
    Type: Application
    Filed: August 15, 2006
    Publication date: December 7, 2006
    Inventors: Jorge Brioni, Teodozyj Kolasa, Gin Hsieh, Diana Donnelly-Roberts
  • Prostaglandin endoperoxide H synthase biosynthesis inhibitors
    Patent number: 7115591
    Abstract: The present invention describes pyridazinone compounds of formula I which are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2), COX-2 is the inducible isoform associated with inflammation, as opposed to the constitutive isoform, cyclooxygenase-1 (COX-1) which is an important “housekeeping” enzyme in many tissues, including the gastrointestinal (GI) tract and the kidneys. The selectivity of these compounds for COX-2 minimizes the unwanted GI and renal side-effects seen with currently markered non-steroidal anti-inflammatory drugs (NSAIDs).
    Type: Grant
    Filed: June 19, 2003
    Date of Patent: October 3, 2006
    Assignee: Abbott Laboratories
    Inventors: Lawrence A. Black, Anwer Basha, Teodozyj Kolasa, Michael E. Kort, Huaqing Liu, Catherine M. McCarty, Meena Patel, Jeffrey J. Rohde, Michael J. Coghlan, Andrew O. Stewart
  • Antagonists of the mGlu receptor and uses thereof
    Publication number: 20060189639
    Abstract: The present invention discloses compounds of general formula (I) wherein X1-X4 and R1-R3 are as defined in the description. The present invention also discloses methods of treatment for pain, neurodegeneration and convulsive states in a host mammal in need thereof, and pharmaceutical compositions including those compounds.
    Type: Application
    Filed: January 17, 2006
    Publication date: August 24, 2006
    Inventors: Andrew Stewart, Guo Zheng, Teodozyj Kolasa, Pramila Bhatia, Jerome Daanen, Steven Latshaw, Xueqing Wang
  • Benzimidazoles that are useful in treating male sexual dysfunction
    Patent number: 7022728
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
    Type: Grant
    Filed: March 8, 2002
    Date of Patent: April 4, 2006
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Pramila A. Bhatia, Jerome F. Daanen, Andrew O. Stewart, Meena V. Patel, Teodozyj Kolasa, Jorge D. Brioni, Jeffrey Rohde
  • Prostaglandin endoperoxide H synthase biosynthesis inhibitors
    Patent number: 7001895
    Abstract: The present invention describes pyridazinone compounds of formula I which are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2). COX-2 is the inducible isoform associated with inflammation, as opposed to the constitutive isoform, cyclooxygenase-1 (COX-1) which is an important “housekeeping” enzyme in many tissues, including the gastrointestinal (GI) tract and the kidneys. The selectivity of these compounds for COX-2 minimizes the unwanted GI and renal side-effects seen with currently marketed non-steroidal anti-inflammatory drugs (NSAIDs).
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: February 21, 2006
    Assignee: Abbott Laboratories
    Inventors: Lawrence A. Black, Anwer Basha, Teodozyj Kolasa, Michael E. Kort, Huaqing Liu, Catherine M. McCarty, Meena Patel, Jeffrey J. Rohde, Michael J. Coghlan, Andrew O. Stewart
  • Acetamides and benzamides that are useful in treating sexual dysfunction
    Publication number: 20060009461
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
    Type: Application
    Filed: September 9, 2005
    Publication date: January 12, 2006
    Inventors: Pramila Bhatia, Jerome Daanen, Ahmed Hakeem, Teodozyj Kolasa, Mark Matulenko, Kathleen Mortell, Meena Patel, Andrew Stewart, Xueqing Wang, Zhiren Xia, Henry Zhang
  • Benzimidazoles that are useful in treating sexual dysfunction
    Patent number: 6960589
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction, wherein L is C1-4 alkyl; RA, RB, RC, RD, and RE, are as described in the specification; Z is selected from the group consisting of N, C and CH; and A is aryl and heteroaryl as described in the specification.
    Type: Grant
    Filed: September 6, 2002
    Date of Patent: November 1, 2005
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Pramila A. Bhatia, Jerome F. Daanen, Andrew O. Stewart, Meena V. Patel, Teodozyj Kolasa, Jorge D. Brioni, Jeffrey Rohde, Kenneth M. Engstrom
  • Novel amides that activate soluble guanylate cyclase
    Publication number: 20040192680
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: December 18, 2003
    Publication date: September 30, 2004
    Inventors: Steven N. Anderson, Pramila A. Bhatia, Teodozyj Kolasa, Masaki Nakane, Meena V. Patel, Jeffrey J. Rohde, Xia Zhiren, Henry Qing-Wei Zhang
  • Prostaglandin endoperoxide H synthase biosynthesis inhibitors
    Publication number: 20040158064
    Abstract: The present invention describes pyridazinone compounds of formula I 1
    Type: Application
    Filed: June 19, 2003
    Publication date: August 12, 2004
    Inventors: Lawrence A. Black, Anwer Basha, Teodozyj Kolasa, Michael E. Kort, Huaqing Liu, Catherine M. McCarty, Meena Patel, Jeffrey J. Rohde, Michael J. Coghlan, Andrew O. Stewart
  • Novel amides that activate soluble guanylate cyclase
    Publication number: 20040121994
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: December 20, 2002
    Publication date: June 24, 2004
    Inventors: Steven N. Anderson, Pramila Bhatia, Teodozyj Kolasa, Masaki Nakane, Meena V. Patel, Jeffrey J. Rohde, Zhiren Xia, Henry Q. Zhang
  • Benzimidazoles that are useful in treating sexual dysfunction
    Publication number: 20040110766
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: October 31, 2003
    Publication date: June 10, 2004
    Inventors: Marlon D. Cowart, Pramila A. Bhatia, Jerome F. Daanen, Andrew O. Stewart, Meena V. Patel, Teodozyj Kolasa, Jorge D. Brioni, Jeffrey Rohde
  • Indazole derivatives that are activators of soluble guanylate cyclase
    Publication number: 20040048866
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: February 26, 2003
    Publication date: March 11, 2004
    Inventors: Teodozyj Kolasa, Jorge D. Brioni, Vijaya Gracias, Masaki Nakane, Meena V. Patel, Jeffrey Rohde
  • Acetamides and benzamides that are useful in treating sexual dysfunction
    Publication number: 20040029887
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: April 29, 2003
    Publication date: February 12, 2004
    Inventors: Pramila A. Bhatia, Jerome F. Daanen, Ahmed A. Hakeem, Teodozyj Kolasa, Mark A. Matulenko, Kathleen H. Mortell, Meena V. Patel, Andrew O. Stewart, Xueqing Wang, Zhiren Xia, Henry Q. Zhang
  • Acetamides and benzamides that are useful in treating sexual dysfunction
    Publication number: 20030232836
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: May 23, 2002
    Publication date: December 18, 2003
    Inventors: Andrew O. Stewart, Teodozyj Kolasa
  • Acetamides and benzamides that are useful in treating sexual dysfunction
    Publication number: 20030229094
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: May 23, 2003
    Publication date: December 11, 2003
    Inventors: Pramila A. Bhatia, Jerome F. Daanen, Ahmed A. Hakeem, Teodozyj Kolasa, Mark A. Matulenko, Kathleen H. Mortell, Meena V. Patel, Andrew O. Stewart, Xueqing Wang, Zhiren Xia, Henry Q. Zhang