Patents by Inventor Terence Butters

Terence Butters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutically active piperidine derivatives
    Publication number: 20060074107
    Abstract: Compounds of formula (I): wherein R represents various substituent groups, are useful as inhibitors of glucosylceramide synthase.
    Type: Application
    Filed: August 3, 2005
    Publication date: April 6, 2006
    Inventors: Terence Butters, Raymond Dwek, George Fleet, Michael Orchard, Frances Platt
  • Therapeutic compositions and methods of treating glycolipid storage related disorders
    Publication number: 20050075305
    Abstract: A method for treating a glycolipid storage-related disorder, comprising administering a therapeutically effective amount of an inhibitor of glycolipid synthesis in combination with an agent capable of increasing the rate of glycolipid degradation or in combination with bone marrow transplantation. Inhibitors of glycolipid synthesis include N-butyldeoxynojirimycin (NB-DNJ), N-butyldeoxygalactonojirimycin (NB-DGJ) or N-nonyldeoxynojirimycin (NN-DNJ). Glycolipid storage-related disorders include Gaucher disease, Sandhoff's disease, Fabry's disease, Tay-Sach's disease, Niemann-Pick C storage disease, GM1 gangliosidosis, genetic disorders in which neuronal glycolipid accumulation contributes to disease pathology.
    Type: Application
    Filed: January 15, 2004
    Publication date: April 7, 2005
    Inventors: Raymond Dwek, Terence Butters, Mylvaganam Jeyakumar, Frances Platt, David Priestman