Patents by Inventor Terence E. Martin

Terence E. Martin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors
    Patent number: 8791068
    Abstract: A novel group of gastrokines called Gastric Antrum Mucosal Protein is characterized. A member of the group is designated AMP-18. AMP-18 genomic DNA, cDNA and the AMP-18 protein are sequenced for human, mouse and pig. The AMP-18 protein and active peptides derived from it are cellular growth factors. Surprisingly, peptides capable of inhibiting the effects of the complete protein, are also derived from the AMP-18 protein. Cytoprotection and control of mammalian gastro-intestinal tissue growth and repair (restitution) is facilitated by the use of the proteins, making the proteins candidates for therapies in inflammatory bowel disease and gastric ulcers.
    Type: Grant
    Filed: August 30, 2012
    Date of Patent: July 29, 2014
    Assignee: The University of Chicago
    Inventors: Terence E. Martin, F. Gary Toback, Margaret Walsh-Reitz
  • Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors
    Patent number: 8741838
    Abstract: A novel group of gastrokines called Gastric Antrum Mucosal Protein is characterized. A member of the group is designated AMP-18. AMP-18 genomic DNA, cDNA and the AMP-18 protein are sequenced for human, mouse and pig. The AMP-18 protein and active peptides derived from it are cellular growth factors. Surprisingly, peptides capable of inhibiting the effects of the complete protein, are also derived from the AMP-18 protein. Cytoprotection and control of mammalian gastro-intestinal tissue growth and repair (restitution) is facilitated by the use of the proteins, making the proteins candidates for therapies in inflammatory bowel disease, mucositis, and gastric ulcers.
    Type: Grant
    Filed: March 8, 2011
    Date of Patent: June 3, 2014
    Assignee: The University of Chicago
    Inventors: F. Gary Toback, Terence E. Martin, Margaret M. Walsh-Reitz
  • CONTROL OF GROWTH AND REPAIR OF GASTRO-INTESTINAL TISSUES BY GASTROKINES AND INHIBITORS
    Publication number: 20110245168
    Abstract: A novel group of gastrokines called Gastric Antrum Mucosal Protein is characterized. A member of the group is designated AMP-18. AMP-18 genomic DNA, cDNA and the AMP-18 protein are sequenced for human, mouse and pig. The AMP-18 protein and active peptides derived from it are cellular growth factors. Surprisingly, peptides capable of inhibiting the effects of the complete protein, are also derived from the AMP-18 protein. Cytoprotection and control of mammalian gastro-intestinal tissue growth and repair (restitution) is facilitated by the use of the proteins, making the proteins candidates for therapies in inflammatory bowel disease, mucositis, and gastric ulcers.
    Type: Application
    Filed: March 8, 2011
    Publication date: October 6, 2011
    Applicant: THE UNIVERSITY OF CHICAGO
    Inventors: F. Gary Toback, Terence E. Martin, Margaret M. Walsh-Reitz
  • Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors
    Patent number: 7910543
    Abstract: A novel group of gastrokines called Gastric Antrum Mucosal Protein is characterized. A member of the group is designated AMP-18. AMP-18 genomic DNA, cDNA and the AMP-18 protein are sequenced for human, mouse and pig. The AMP-18 protein and active peptides derived from it are cellular growth factors. Surprisingly, peptides capable of inhibiting the effects of the complete protein, are also derived from the AMP-18 protein. Cytoprotection and control of mammalian gastro-intestinal tissue growth and repair (restitution) is facilitated by the use of the proteins, making the proteins candidates for therapies in inflammatory bowel disease, mucositis, and gastric ulcers.
    Type: Grant
    Filed: October 23, 2009
    Date of Patent: March 22, 2011
    Assignee: The University of Chicago
    Inventors: F. Gary Toback, Terence E. Martin, Margaret M. Walsh-Reitz
  • CONTROL OF GROWTH AND REPAIR OF GASTRO-INTESTINAL TISSUES BY GASTROKINES AND INHIBITORS
    Publication number: 20100113356
    Abstract: A novel group of gastrokines called Gastric Antrum Mucosal Protein is characterized. A member of the group is designated AMP-18. AMP-18 genomic DNA, cDNA and the AMP-18 protein are sequenced for human, mouse and pig. The AMP-18 protein and active peptides derived from it are cellular growth factors. Surprisingly, peptides capable of inhibiting the effects of the complete protein, are also derived from the AMP-18 protein. Cytoprotection and control of mammalian gastro-intestinal tissue growth and repair (restitution) is facilitated by the use of the proteins, making the proteins candidates for therapies in inflammatory bowel disease, mucositis, and gastric ulcers.
    Type: Application
    Filed: October 23, 2009
    Publication date: May 6, 2010
    Applicant: THE UNIVERSITY OF CHICAGO
    Inventors: F. Gary Toback, Terence E. Martin, Margaret M. Walsh-Reitz
  • Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors
    Patent number: 7629317
    Abstract: A novel group of gastrokines called Gastric Antrum Mucosal Protein is characterized. A member of the group is designated AMP-18. AMP-18 genomic DNA, cDNA and the AMP-18 protein are sequenced for human, mouse and pig. The AMP-18 protein and active peptides derived from it are cellular growth factors. Surprisingly, peptides capable of inhibiting the effects of the complete protein, are also derived from the AMP-18 protein. Cytoprotection and control of mammalian gastro-intestinal tissue growth and repair (restitution) is facilitated by the use of the proteins, making the proteins candidates for therapies in inflammatory bowel disease, mucositis, and gastric ulcers.
    Type: Grant
    Filed: May 11, 2004
    Date of Patent: December 8, 2009
    Assignee: The University of Chicago
    Inventors: F. Gary Toback, Terence E. Martin, Margaret M. Walsh-Reitz
  • Gastrokines and derived peptides including inhibitors
    Patent number: 7557083
    Abstract: A novel group of gastrokines called Gastric Antrum Mucosal Protein is characterized. A member of the group is designated AMP-18. AMP-18 genomic DNA, cDNA and the AMP-18 protein are sequenced for human, mouse and pig. The AMP-18 protein and active peptides derived from it are cellular growth factors. Surprisingly, peptides capable of inhibiting the effects of the complete protein, are also derived from the AMP-18 protein. Control of mammalian gastro-intestinal tissues growth and repair is facilitated by the use of the proteins, making the proteins candidates for therapies.
    Type: Grant
    Filed: March 29, 2002
    Date of Patent: July 7, 2009
    Assignee: The University of Chicago
    Inventors: Terence E. Martin, F. Gary Toback, Thomas C. Powell, Miriana Choudhary, legal representative, Kan Agarwal
  • Aerofoil members for gas turbine engines
    Patent number: 5641268
    Abstract: Aerofoil members such as the stator vanes and rotor blades of an axial flow compressor are defined by a number of nominal sections. The leading edge of each nominal section of the blade is set so that an airflow passing therethrough is incident at the optimum angle. The optimum angle is chosen so that the maximum velocities of the airflow at the leading edge are equal. Once the optimum angle has been found for each section of the blade the sections are stacked to define a blade having a leading edge the aerodynamic profile of which ensures that the airflow is incident at the optimum angle along the length of the blade from the root to the tip. The efficiency of the axial flow compressor is improved.
    Type: Grant
    Filed: February 9, 1996
    Date of Patent: June 24, 1997
    Assignee: Rolls-Royce plc
    Inventors: Terence E. Martin, Hang W. Lung