Patents by Inventor Terence Hamill

Terence Hamill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alkyne derivatives as tracers for metabotropic glutamate receptor binding
    Publication number: 20070060618
    Abstract: The present invention is directed to isotopically labeled alkyne derivative compounds, particularly 11C, 13C, 14C, 18F, 15O, 13N, 35S, 2H, and 3H labeled compounds. In particular, the present invention is directed to 11C, 13C, 14C, 18F, 15O, 13N, 35S, 2H, and 3H labeled heterocyclic alkynes and methods of their preparation. The present invention further includes a method of use of the 11C, 18F, 15O, or 13N labeled heterocyclic alkyne compounds as tracers in positron emission tomography (PET) imaging, particularly in the study of metabolic conditions in mammals, specifically conditions modulated by metabotropic glutamate receptors subtype 5 (mGluR5).
    Type: Application
    Filed: October 24, 2003
    Publication date: March 15, 2007
    Applicant: MERCK & CO., INC.
    Inventors: Nicholas David Cosford, Steven Govck, Terence Hamill, Theodore Kamenecka, Thomas Seiders, Jeffrey Roppe, Celine Bonnefous, Donald Burns, Matthew Braun, Dennis Dean, Joseph Simeone
  • Substituted amides
    Publication number: 20060115425
    Abstract: The present invention relates to particular radiolabeled Cannabinoid-1 (CB1) receptor modulators, and methods of using these modulators for labeling and diagnostic imaging of Cannabinoid-1 receptors in mammals, particularly humans. In addition, intermediates useful for the synthesis of the radiolabeled Cannabinoid-1 receptor modulators are also disclosed, as well as the processes for synthesizing the radiolabeled Cannabinoid-1 receptor modulators. Still further, formulations of the radiolabeled Cannabinoid-1 receptor compounds are described.
    Type: Application
    Filed: June 25, 2004
    Publication date: June 1, 2006
    Inventors: H. Donald Burns, Alex Chen, Raymond Gibson, Mark Goulet, William Hagmann, Terence Hamill, James Jewell, Linus Lin, Ping Liu, Andrey Peresypkin
  • Radiolabeled neurokinin-1 receptor antagonists
    Publication number: 20050214204
    Abstract: The present invention is directed to radiolabeled neurokinin-1 receptor antagonists which are useful for the labeling and diagnostic imaging of neurokinin-1 receptors in mammals.
    Type: Application
    Filed: September 19, 2003
    Publication date: September 29, 2005
    Inventors: H. Donald Burns, Wai-si Eng, Raymond Gibson, Terence Hamill